Displaying drugs 13226 - 13250 of 13918 in total
Cannabivarin
A natural product found in Cannabis sativa.
Experimental
Matched Iupac: … 6,6,9-trimethyl-3-propyl-6H-benzo[c]chromen-1-ol …
Matched Description: … A natural product found in Cannabis sativa. …
Matched Description: … A natural product found in Cannabis sativa. …
BBP-711
BBP-711 is a glycolate oxidase inhibitor.
Investigational
Matched Description: … BBP-711 is a glycolate oxidase inhibitor. …
Lexacalcitol
Lexacalcitol is a solid. This compound belongs to the vitamin D and derivatives class of chemicals. These are compounds containing a secosteroid backbone, usually secoergostane or secocholestane. It is known to target the vitamin D3 receptor.
Experimental
Matched Iupac: … (1R,3S,5Z)-5-{2-[(1S,3aS,4E,7aS)-1-[(1R)-1-[(4-ethyl-4-hydroxyhexyl)oxy]ethyl]-7a-methyl-octahydro-1H-inden …
Matched Description: … Lexacalcitol is a solid. This compound belongs to the vitamin D and derivatives class of chemicals. ... These are compounds containing a secosteroid backbone, usually secoergostane or secocholestane. …
Matched Description: … Lexacalcitol is a solid. This compound belongs to the vitamin D and derivatives class of chemicals. ... These are compounds containing a secosteroid backbone, usually secoergostane or secocholestane. …
Elsamitrucin
The cytostatic agent Elsamitrucin is a new fermentation product active in a variety of in vivo tumor models of murine and human origin. (PMID: 8150873)
Investigational
Matched Iupac: … }]icosa-1(19),2(7),3,5,8,12(20),13,15-octaene-10,17-dione ... 3-{[(2S,3R,4S,5S,6R)-3-{[(2R,3R,4R,5S,6R)-3-amino-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-4,5-dihydroxy ... -4,6-dimethyloxan-2-yl]oxy}-8-hydroxy-15-methyl-11,18-dioxapentacyclo[10.6.2.0^{2,7}.0^{9,19}.0^{16,20 …
Matched Description: … The cytostatic agent Elsamitrucin is a new fermentation product active in a variety of in vivo tumor …
Matched Description: … The cytostatic agent Elsamitrucin is a new fermentation product active in a variety of in vivo tumor …
Milvexian
Milvexian is under investigation in clinical trial NCT03766581 (A Study on BMS-986177 for the Prevention of a Stroke in Patients Receiving Aspirin and Clopidogrel).
Investigational
Matched Iupac: … (9R,13S)-13-{4-[5-chloro-2-(4-chloro-1H-1,2,3-triazol-1-yl)phenyl]-6-oxo-1,6-dihydropyrimidin-1-yl}-3 ... -(difluoromethyl)-9-methyl-3,4,7,15-tetraazatricyclo[12.3.1.0^{2,6}]octadeca-1(17),2(6),4,14(18),15-pentaen …
Matched Description: … of a Stroke in Patients Receiving Aspirin and Clopidogrel). ... Milvexian is under investigation in clinical trial NCT03766581 (A Study on BMS-986177 for the Prevention …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … of a Stroke in Patients Receiving Aspirin and Clopidogrel). ... Milvexian is under investigation in clinical trial NCT03766581 (A Study on BMS-986177 for the Prevention …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
BI-836880
BI-836880 is a humanized bispecific nanobody that targets VEGF and Ang2.
Investigational
Matched Description: … BI-836880 is a humanized bispecific nanobody that targets VEGF and Ang2. …
Dutogliptin
Dutogliptin has been investigated for the treatment of Diabetes Mellitus, Type II.
Investigational
Matched Iupac: … [(2R)-1-(2-{[(3R)-pyrrolidin-3-yl]amino}acetyl)pyrrolidin-2-yl]boronic acid …
Elsiglutide
Investigational
CT-011
CT-011 is a humanized monoclonal antibody directed against a B7 family-associated protein, in patients with advanced haematological malignancies. It is directed against human PD-1 (programmed cell death 1; PDCD1), with immunomodulating and antitumor activities.
Investigational
Matched Description: … CT-011 is a humanized monoclonal antibody directed against a B7 family-associated protein, in patients ... It is directed against human PD-1 (programmed cell death 1; PDCD1), with immunomodulating and antitumor …
Manitimus
FK778, a novel compound with multiple mechanisms of action, is efficacious, well tolerated and safe in kidney transplant patients, potentially offering a breakthrough in immunosuppressive therapy.
Investigational
Matched Iupac: … (2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]hept-2-en-6-ynamide …
Matched Description: … kidney transplant patients, potentially offering a breakthrough in immunosuppressive therapy. ... FK778, a novel compound with multiple mechanisms of action, is efficacious, well tolerated and safe in …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … kidney transplant patients, potentially offering a breakthrough in immunosuppressive therapy. ... FK778, a novel compound with multiple mechanisms of action, is efficacious, well tolerated and safe in …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Ladarixin
Ladarixin is under investigation in clinical trial NCT04628481 (A Study of Oral Ladarixin in New-onset Type 1 Diabetes and a Low Residual Β-Cell Function).
Investigational
Matched Iupac: … 4-[(1R)-1-(methanesulfonylcarbamoyl)ethyl]phenyl trifluoromethanesulfonate …
Matched Description: … Type 1 Diabetes and a Low Residual Β-Cell Function). ... Ladarixin is under investigation in clinical trial NCT04628481 (A Study of Oral Ladarixin in New-onset …
Matched Description: … Type 1 Diabetes and a Low Residual Β-Cell Function). ... Ladarixin is under investigation in clinical trial NCT04628481 (A Study of Oral Ladarixin in New-onset …
TAK-611
TAK-611, formerly known as SHP611, is a recombinant human arylsulfatase A. First developed by Takeda, it is being investigated for the treatment of metachromatic leukodystrophy.
Investigational
Matched Description: … TAK-611, formerly known as SHP611, is a recombinant human arylsulfatase A. …
Sumanirole
Investigational
Matched Iupac: … (10R)-10-(methylamino)-1,3-diazatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
RUS 3108
RUS 3108 is being developed for the treatment of atherosclerosis, the major cause of cardiovascular disorders such as heart attacks and stroke by Dr. Reddy’s Laboratories.
The drug’s Phase I clinical trials have been initiated in Europe to assess safety of the drug compound in healthy volunteers.
Investigational
IR502
IR502 (Zorcell) is a potential treatment for psoriasis.
Investigational
Matched Description: … IR502 (Zorcell) is a potential treatment for psoriasis. …
WIN-54954
WIN-54954 is a broad-spectrum antipicornavirus drug.
Experimental
Matched Iupac: … 5-{5-[2,6-dichloro-4-(4,5-dihydro-1,3-oxazol-2-yl)phenoxy]pentyl}-3-methyl-1,2-oxazole …
Matched Description: … WIN-54954 is a broad-spectrum antipicornavirus drug. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … WIN-54954 is a broad-spectrum antipicornavirus drug. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Sacubitrilat
A metabolite of LCZ696 with neprilysin inhibitory activity.
Experimental
Matched Iupac: … (2R,4S)-5-{[1,1'-biphenyl]-4-yl}-4-(3-carboxypropanamido)-2-methylpentanoic acid …
Matched Description: … A metabolite of LCZ696 with neprilysin inhibitory activity. …
Matched Description: … A metabolite of LCZ696 with neprilysin inhibitory activity. …
CP-39,332
CP-39,332 is a serotonin-norepinephrine reuptake inhibitor (SNRI). It is part of a group of monoamine reuptake inhibitor stereoisomers including tametraline (1R,4S-), CP-24,442 (1S,4R-), CP-22,185 (cis-), and CP-22,186 that show varying efficiency. However, none of the members of this stereoisomers has been marketed.
Experimental
Matched Iupac: … N-methyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-2-amine …
Matched Description: … CP-39,332 is a serotonin-norepinephrine reuptake inhibitor (SNRI). ... It is part of a group of monoamine reuptake inhibitor stereoisomers including tametraline (1R,4S-), CP …
Matched Description: … CP-39,332 is a serotonin-norepinephrine reuptake inhibitor (SNRI). ... It is part of a group of monoamine reuptake inhibitor stereoisomers including tametraline (1R,4S-), CP …
FP0011
FP0011 is a small molecule antiglutamatergic compound with symptomatic and disease modifying effects in a variety of neurological disorders (amyotrophic lateral sclerosis and Parkinson's disease). It acts on the presynaptic regulation of glutamate and shows strong neuroprotective properties.
Investigational
Matched Description: … FP0011 is a small molecule antiglutamatergic compound with symptomatic and disease modifying effects ... in a variety of neurological disorders (amyotrophic lateral sclerosis and Parkinson's disease). …
SNS01-T
SNS01-T is a gene therapy nanoparticle. It is composed of three components: a B cell-specific plasmid expressing eIF5AK50R; an siRNA that targets the native eIF5A that promotes growth/anti-apoptosis of cancer cells; and polyethylenimine.
Investigational
Matched Description: … It is composed of three components: a B cell-specific plasmid expressing eIF5AK50R; an siRNA that targets ... SNS01-T is a gene therapy nanoparticle. …
BMN-351
BMN-351 is a fully modified 18-mer oligonucleotide with a TEG modification at its 5' end that binds to exon 51 of dystrophin pre-mRNA. It is under investigation for the treatment of Duchenne Muscular Dystrophy (DMD).
Investigational
Matched Description: … BMN-351 is a fully modified 18-mer oligonucleotide with a TEG modification at its 5' end that binds to …
PF-04418948
Pf 04418948 is under investigation in clinical trial NCT01002963 (A Study To Investigate The Safety And Toleration Of A Single Dose Of PF-04418948 In Healthy Volunteers).
Investigational
Matched Iupac: … 1-(4-fluorobenzoyl)-3-{[(6-methoxynaphthalen-2-yl)oxy]methyl}azetidine-3-carboxylic acid …
Matched Description: … Toleration Of A Single Dose Of PF-04418948 In Healthy Volunteers). ... Pf 04418948 is under investigation in clinical trial NCT01002963 (A Study To Investigate The Safety And …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Toleration Of A Single Dose Of PF-04418948 In Healthy Volunteers). ... Pf 04418948 is under investigation in clinical trial NCT01002963 (A Study To Investigate The Safety And …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Pafuramidine
Pafuramidine, a prodrug of furamidine, currently has orphan status for Pneumocystis jiroveci pneumonia.
Investigational
Matched Iupac: … N-methoxy-4-{5-[4-(N-methoxycarbamimidoyl)phenyl]furan-2-yl}benzene-1-carboximidamide …
Matched Description: … Pafuramidine, a prodrug of furamidine, currently has orphan status for _Pneumocystis jiroveci_ pneumonia …
Matched Salts cas: … 837369-26-3 …
Matched Description: … Pafuramidine, a prodrug of furamidine, currently has orphan status for _Pneumocystis jiroveci_ pneumonia …
Matched Salts cas: … 837369-26-3 …
Stibophen
Stibophen is used in the treatment of schistosomiasis, a disease of parasitic flatworms.
Experimental
Matched Iupac: … antimony(3+) ion pentasodium bis(3,5-disulfobenzene-1,2-bis(olate)) heptahydrate …
Matched Description: … Stibophen is used in the treatment of schistosomiasis, a disease of parasitic flatworms. …
Matched Description: … Stibophen is used in the treatment of schistosomiasis, a disease of parasitic flatworms. …
Displaying drugs 13226 - 13250 of 13918 in total