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Displaying drugs 13326 - 13350 of 13806 in total

Typhonium giganteum whole

Typhonium giganteum whole is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Typhonium giganteum whole is a plant/plant extract used in some OTC (over-the-counter) products. …

Fenebrutinib

Fenebrutinib is under investigation in clinical trial NCT03174041 (A Drug-Drug Interaction Study Between GDC-0853 and Midazolam, Itraconazole, Rosuvastatin, and Simvastatin).
Investigational
Matched Iupac: … 10-[3'-(hydroxymethyl)-1-methyl-5-({5-[(2S)-2-methyl-4-(oxetan-3-yl)piperazin-1-yl]pyridin-2-yl}amino ... )-6-oxo-1,6-dihydro-[3,4'-bipyridin]-2'-yl]-4,4-dimethyl-1,10-diazatricyclo[6.4.0.0^{2,6}]dodeca-2(6) …
Matched Description: … Fenebrutinib is under investigation in clinical trial NCT03174041 (A Drug-Drug Interaction Study Between …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Tavolixizumab

Tavolixizumab is under investigation in clinical trial NCT02318394 (A Phase 1 Study of MEDI0562 in Adult Subjects With Selected Advanced Solid Tumors).
Investigational
Matched Description: … Tavolixizumab is under investigation in clinical trial NCT02318394 (A Phase 1 Study of MEDI0562 in Adult …

Ramatercept

Ramatercept is under investigation in clinical trial NCT00952887 (A Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study of ACE-031 in Healthy Postmenopausal Women).
Investigational
Matched Description: … Ramatercept is under investigation in clinical trial NCT00952887 (A Safety, Tolerability, Pharmacokinetic …

Mesdopetam

Mesdopetam is under investigation in clinical trial NCT04435431 (A Clinical Study of Mesdopetam in Patients With Parkinson's Disease Experiencing Levodopa Induced Dyskinesia).
Investigational
Matched Iupac: … [2-(3-fluoro-5-methanesulfonylphenoxy)ethyl](propyl)amine …
Matched Description: … Mesdopetam is under investigation in clinical trial NCT04435431 (A Clinical Study of Mesdopetam in Patients …

Olaparib-bodipy FL

Olaparib-bodipy FL is under investigation in clinical trial NCT03085147 (A Dye for the Detection of Cancer of the Tongue and Mouth).
Investigational
Matched Iupac: … 2,2-difluoro-12-[3-(4-{2-fluoro-5-[(4-oxo-3,4-dihydrophthalazin-1-yl)methyl]benzoyl}piperazin-1-yl)-3 ... 1-ylium-2-uide ... -oxopropyl]-4,6-dimethyl-1lambda5,3-diaza-2-boratricyclo[7.3.0.0^{3,7}]dodeca-1(12),4,6,8,10-pentaen- …
Matched Description: … Olaparib-bodipy FL is under investigation in clinical trial NCT03085147 (A Dye for the Detection of Cancer …

Eltrekibart

Eltrekibart is under investigation in clinical trial NCT06046729 (A Study of Eltrekibart (LY3041658) in Adult Participants With Moderate to Severe Hidradenitis Suppurativa).
Investigational
Matched Description: … Eltrekibart is under investigation in clinical trial NCT06046729 (A Study of Eltrekibart (LY3041658) …

Cytidine-5'-Triphosphate

Cytidine 5'-(tetrahydrogen triphosphate). A cytosine nucleotide containing three phosphate groups esterified to the sugar moiety. [PubChem]
Experimental
Matched Iupac: … ({[({[(2R,3S,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy …
Matched Description: … Cytidine 5'-(tetrahydrogen triphosphate). ... A cytosine nucleotide containing three phosphate groups esterified to the sugar moiety. [PubChem] …

Guanosine-5'-Triphosphate

Guanosine 5'-(tetrahydrogen triphosphate). A guanine nucleotide containing three phosphate groups esterified to the sugar moiety. [PubChem]
Experimental
Matched Iupac: … ({[({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy …
Matched Description: … Guanosine 5'-(tetrahydrogen triphosphate). ... A guanine nucleotide containing three phosphate groups esterified to the sugar moiety. [PubChem] …

TAK-751S

TAK-751S is a synthetic analog of Shiga toxin (Stx) receptor, Gb3, produced by enterohemorrhagic Escherichia coli.
Investigational
Matched Description: … TAK-751S is a synthetic analog of Shiga toxin (Stx) receptor, Gb3, produced by enterohemorrhagic _Escherichia …

Thiorphan

A potent inhibitor of membrane metalloendopeptidase (enkephalinase). Thiorphan potentiates morphine-induced analgesia and attenuates naloxone-precipitated withdrawal symptoms.
Experimental
Matched Iupac: … 2-[(2S)-2-benzyl-3-sulfanylpropanamido]acetic acid …
Matched Description: … A potent inhibitor of membrane metalloendopeptidase (enkephalinase). …
Matched Categories: … N-substituted Glycines …

Tibulizumab

Tibulizumab is under investigation in clinical trial NCT03736772 (A Study of LY3090106 in Japanese and Caucasian Healthy Participants).
Investigational
Matched Description: … Tibulizumab is under investigation in clinical trial NCT03736772 (A Study of LY3090106 in Japanese and …

FCX-013

FCX-013 consists of human dermal fibroblasts genetically modified with a lentiviral vector expressing metalloproteinase-1 (MMP-1).
Investigational
Matched Description: … metalloproteinase-1 (MMP-1). ... FCX-013 consists of human dermal fibroblasts genetically modified with a lentiviral vector expressing …

BJ-001

BJ-001 is a recombinant human interleukin-15/IL-15 receptor alpha complex with linked integrin-binding motif.
Investigational
Matched Description: … BJ-001 is a recombinant human interleukin-15/IL-15 receptor alpha complex with linked integrin-binding …

MBX-2109

MBX-2109 is a long-acting parathyroid hormone peptide prodrug under investigation for the treatment of hyperparathyroidism.
Investigational
Matched Description: … MBX-2109 is a long-acting parathyroid hormone peptide prodrug under investigation for the treatment of …

Zigakibart

Zigakibart is under investigation in clinical trial NCT05852938 (A Study of BION-1301 in Adults With Iga Nephropathy).
Investigational
Matched Description: … Zigakibart is under investigation in clinical trial NCT05852938 (A Study of BION-1301 in Adults With …

JB991

JB991 is a cyclopentenone prostaglandin analogue intended for treatment of psoriasis. The drug exerts marked antiproliferative and pro-apoptotic effect in human keratinocytes and fibroblasts in vitro. In addition a closely related cyclopentenone prostaglandin analogue has been shown to exert marked anti-inflammatory effect in vivo in an animal model. The drug...
Investigational
Matched Description: … JB991 is a cyclopentenone prostaglandin analogue intended for treatment of psoriasis. ... In addition a closely related cyclopentenone prostaglandin analogue has been shown to exert marked anti-inflammatory …

5-(3-(2,6-dichloro-4-(4,5-dihydro-2-oxazolyl)phenoxy)propyl)-3-methyl isoxazole

5-(3-(2,6-dichloro-4-(4,5-dihydro-2-oxazolyl)phenoxy)propyl)-3-methyl isoxazole is a solid. This compound belongs to the phenol ethers. These are aromatic compounds containing an ether group substituted with a benzene ring. Known drug targets of 5-(3-(2,6-dichloro-4-(4,5-dihydro-2-oxazolyl)phenoxy)propyl)-3-methyl isoxazole include genome polyprotein.
Experimental
Matched Name: … 5-(3-(2,6-dichloro-4-(4,5-dihydro-2-oxazolyl)phenoxy)propyl)-3-methyl isoxazole …
Matched Iupac: … 5-{3-[2,6-dichloro-4-(4,5-dihydro-1,3-oxazol-2-yl)phenoxy]propyl}-3-methyl-1,2-oxazole …
Matched Description: … 5-(3-(2,6-dichloro-4-(4,5-dihydro-2-oxazolyl)phenoxy)propyl)-3-methyl isoxazole is a solid. ... Known drug targets of 5-(3-(2,6-dichloro-4-(4,5-dihydro-2-oxazolyl)phenoxy)propyl)-3-methyl isoxazole ... These are aromatic compounds containing an ether group substituted with a benzene ring. …

METHYL (3R)-3-{[(3R)-3-{[(3R)-3-HYDROXYBUTANOYL]OXY}BUTANOYL]OXY}BUTANOATE

Experimental
Matched Name: … METHYL (3R)-3-{[(3R)-3-{[(3R)-3-HYDROXYBUTANOYL]OXY}BUTANOYL]OXY}BUTANOATE …
Matched Iupac: … (2R)-4-{[(2R)-4-methoxy-4-oxobutan-2-yl]oxy}-4-oxobutan-2-yl (3R)-3-hydroxybutanoate …

Orgotein

Superoxide is a natural byproduct of oxygen metabolism which, if left unchecked, leads to cell damage. Superoxide dismutase (SOD) is an enzyme that alternately catalyzes the dismutation of the superoxide radical into either the less damaging hydrogen peroxide or molecular oxygen. Hydrogen peroxide can be degraded by catalase. The antioxidant...
Investigational
Vet approved
Matched Description: … A notable exception is Lactobacillus plantarum. ... Superoxide is a natural byproduct of oxygen metabolism which, if left unchecked, leads to cell damage …

Elocalcitol

Elocalcitol is a calcitriol analog for inhibition of prostate cell growth; in phase II clinical trial in patients with benign prostate hyperplasia (4/2004).
Investigational
Matched Iupac: … (1R,3Z,5S)-3-{2-[(3aS,7E,7aS)-3-[(2S,4E)-6-ethyl-6-hydroxyoct-4-en-2-yl]-3a-methyl-3a,4,5,6,7,7a-hexahydro ... -1H-inden-7-ylidene]ethylidene}-5-fluoro-4-methylidenecyclohexan-1-ol …
Matched Description: … Elocalcitol is a calcitriol analog for inhibition of prostate cell growth; in phase II clinical trial …

SUVN-G3031

SUVN-G3031 is under investigation in clinical trial NCT02342041 (A Study to Investigate the Safety, Tolerability and Pharmacokinetics of SUVN-G3031 in Healthy Subjects).
Investigational
Matched Iupac: … N-{4-[(1-cyclobutylpiperidin-4-yl)oxy]phenyl}-2-(morpholin-4-yl)acetamide …
Matched Description: … SUVN-G3031 is under investigation in clinical trial NCT02342041 (A Study to Investigate the Safety, Tolerability …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Pimodivir

Pimodivir is under investigation in clinical trial NCT02658825 (A Study to Evaluate the Effect of JNJ-63623872 on Cardiac Repolarization Interval in Healthy Participants).
Investigational
Matched Iupac: … (2S,3S)-3-[(5-fluoro-2-{5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl}pyrimidin-4-yl)amino]bicyclo[2.2.2]octane ... -2-carboxylic acid …
Matched Description: … Pimodivir is under investigation in clinical trial NCT02658825 (A Study to Evaluate the Effect of JNJ …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Domagrozumab

Domagrozumab is under investigation in clinical trial NCT01616277 (A Phase 1 Study To Evaluate The Safety And Tolerability Of PF-06252616 In Healthy Subjects).
Investigational
Matched Description: … Domagrozumab is under investigation in clinical trial NCT01616277 (A Phase 1 Study To Evaluate The Safety …

Rovatirelin

Rovatirelin is under investigation in clinical trial NCT01384435 (A Phase II Double Blind Comparative Study of KPS-0373 in Patients With Spinocerebellar Degeneration (SCD)).
Investigational
Matched Iupac: … (4S,5S)-5-methyl-N-[(2S)-1-[(2R)-2-methylpyrrolidin-1-yl]-1-oxo-3-(1,3-thiazol-4-yl)propan-2-yl]-2-oxo …
Matched Description: … Rovatirelin is under investigation in clinical trial NCT01384435 (A Phase II Double Blind Comparative …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 13326 - 13350 of 13806 in total