Displaying drugs 1326 - 1350 of 1780 in total
Interleukin-7
Interleukin 7 has been used in trials studying the treatment of Metastatic Breast Cancer.
Investigational
Matched Synonyms: … Interleukin-7 human recombinant ... Recombinant human interleukin-7 ... Glycosylated recombinant human interleukin-7 …
Matched Description: … Interleukin 7 has been used in trials studying the treatment of Metastatic Breast Cancer. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … Interleukin 7 has been used in trials studying the treatment of Metastatic Breast Cancer. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Osemitamab
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1, ANTI-(HUMAN CLAUDIN 18.2) (HUMAN-MUS MUSCULUS MONOCLONAL TST001 .GAMMA.1-CHAIN), DISULFIDE ... WITH HUMAN-MUS MUSCULUS MONOCLONAL TST001 .KAPPA. …
Pulocimab
Pulocimab is under investigation in clinical trial NCT06341335 (A Study of Ak104/placebo Plus Ak109/placebo and Paclitaxel in Gastric or Gastroesophageal Junction Adenocarcinoma).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human vascular endothelial growth factor receptor 2) (human monoclonal ak109 ... .gamma.1-chain), disulfide with human monoclonal ak109 .kappa. …
Matched Description: … Pulocimab is under investigation in clinical trial NCT06341335 (A Study of Ak104/placebo Plus Ak109/placebo and …
Matched Description: … Pulocimab is under investigation in clinical trial NCT06341335 (A Study of Ak104/placebo Plus Ak109/placebo and …
Berdazimer
Berdazimer is a polymeric substance consisting of a polysiloxane backbone (Si-O-Si bonds) with covalently bound N-diazeniumdiolate nitric oxide (NO) donors. It releases NO through exposure to proton donors like water, which will degrade the N-diazeniumdiolate entity. Berdazimer was previously investigated as a potential treatment for molluscum contagiosum, a viral cutaneous...
Approved
Matched Synonyms: … Silsesquioxanes, 3-(2-hydroxy-1-methyl-2-nitrosohydrazinyl)propyl 3-(methylamino)propyl, polymers with silicic …
Matched Description: … It is one of the 5 most prevalent skin diseases in the world and the third-most common viral skin infection ... A262960] Berdazimer was previously investigated as a potential treatment for molluscum contagiosum, a viral ... skin discoloration, and fear and anxiety in the pediatric population. …
Matched Categories: … Silicon Compounds …
Matched Description: … It is one of the 5 most prevalent skin diseases in the world and the third-most common viral skin infection ... A262960] Berdazimer was previously investigated as a potential treatment for molluscum contagiosum, a viral ... skin discoloration, and fear and anxiety in the pediatric population. …
Matched Categories: … Silicon Compounds …
Itepekimab
Itepekimab is under investigation in clinical trial NCT03546907 (Proof-of-concept Study to Assess the Efficacy, Safety and Tolerability of SAR440340 (Anti-il-33 Mab) in Patients With Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD)).
Investigational
Matched Synonyms: … Immunoglobulin igg4 (230-proline), anti-(human interleukin 33) (human monoclonal regn3500 .gamma.4-chain ... ), disulfide with human monoclonal regn3500 .kappa. …
Matched Description: … investigation in clinical trial NCT03546907 (Proof-of-concept Study to Assess the Efficacy, Safety and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … investigation in clinical trial NCT03546907 (Proof-of-concept Study to Assess the Efficacy, Safety and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
MS1901
Investigational
Matched Synonyms: … Thrombin-preconditioned allogeneic Wharton's Jelly-derived mesenchymal stem cells …
Dendritic cells vaccine
The recombinant chimeric DC vaccine is a subunit-based vaccine candidate investigated for safety and effectiveness against SARS-CoV-2-induced pneumonia. With a better safety profile than inactivated and live-attenuated virus and virus-vector vaccines, the recombinant chimeric DC vaccine reduces the risk of virulence recovery, pre-existing anti-vector immunity, and incomplete viral inactivation.
As...
Investigational
Matched Name: … Dendritic cells vaccine …
Matched Description: … With a better safety profile than inactivated and live-attenuated virus and virus-vector vaccines, the ... incomplete viral inactivation. ... The recombinant chimeric DC vaccine is a subunit-based vaccine candidate investigated for safety and …
Matched Description: … With a better safety profile than inactivated and live-attenuated virus and virus-vector vaccines, the ... incomplete viral inactivation. ... The recombinant chimeric DC vaccine is a subunit-based vaccine candidate investigated for safety and …
Farletuzumab ecteribulin
Farletuzumab ecteribulin is under investigation in clinical trial NCT04300556 (A Study to Evaluate the Safety, Tolerability, and Efficacy of Morab-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (Frα)-targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types).
Investigational
Matched Synonyms: … Eribulin/farletuzumab antibody drug conjugate …
Matched Description: … is under investigation in clinical trial NCT04300556 (A Study to Evaluate the Safety, Tolerability, and ... Conjugate (ADC) in Participants With Selected Tumor Types). ... Morab-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (Frα)-targeting Antibody-drug …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antibody-drug Conjugates …
Matched Description: … is under investigation in clinical trial NCT04300556 (A Study to Evaluate the Safety, Tolerability, and ... Conjugate (ADC) in Participants With Selected Tumor Types). ... Morab-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (Frα)-targeting Antibody-drug …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antibody-drug Conjugates …
Conestat alfa
C1 Esterase Inhibitor (Recombinant) is a recombinant analogue of endogenous complement component-1 esterase inhibitor (rhC1INH), purified from the milk of transgenic rabbits. The primary function of endogenous C1INH is to regulate the activation of the complement and contact system pathways. It does this through inhibition of several target proteases within...
Approved
Investigational
Matched Synonyms: … Recombinant human C1-INH ... Recombinant human C1 inhibitor ... Recombinant human C1-inhibitor …
Matched Description: … tPA and plasmin within the fibrinolytic pathway. ... The primary function of endogenous C1INH is to regulate the activation of the complement and contact ... of several target proteases within these pathways including activated C1s, kallikrein, factor XIIa and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Description: … tPA and plasmin within the fibrinolytic pathway. ... The primary function of endogenous C1INH is to regulate the activation of the complement and contact ... of several target proteases within these pathways including activated C1s, kallikrein, factor XIIa and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Galiximab
Galiximab is a chimeric monoclonal antibody which is used as an immunosuppressive drug.
Investigational
Matched Synonyms: … Anti-CD80 monoclonal antibody …
Matched Description: … Galiximab is a chimeric monoclonal antibody which is used as an immunosuppressive drug. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Galiximab is a chimeric monoclonal antibody which is used as an immunosuppressive drug. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Morphine
Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength...
Approved
Investigational
Matched Description: … [A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk ... strength such as [codeine], [fentanyl], [methadone], [hydrocodone], [hydromorphone], [meperidine], and …
Matched Categories: … morphine and antispasmodics …
Matched Products: … TWICE ... Bar-morphine SR …
Matched Categories: … morphine and antispasmodics …
Matched Products: … TWICE ... Bar-morphine SR …
Batoclimab
Batoclimab is under investigation in clinical trial NCT04428255 (A Clinical Study on the Efficacy and Safety of HBM9161 in Patients With ITP).
Investigational
Matched Synonyms: … Immunoglobulin g1(238-alanine, 239-alanine), anti-(human fcrn receptor) (human monoclonal hl161bkn .gamma ... .1-chain), disulfide with human monoclonal hl161bkn .lambda. …
Matched Description: … Batoclimab is under investigation in clinical trial NCT04428255 (A Clinical Study on the Efficacy and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Batoclimab is under investigation in clinical trial NCT04428255 (A Clinical Study on the Efficacy and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Tafolecimab
Tafolecimab is under investigation in clinical trial NCT04031742 (A Study to Evaluate Safety and Efficacy of IBI306, a PCSK9 Monoclonal Antibody in Chinese Subjects With Homozygous Familial Hypercholesterolemia).
Investigational
Matched Synonyms: … Immunoglobulin igg2, anti-(human proprotein convertase subtilisin/kexin type 9) (human monoclonal ibi306 ... .gamma.2-chain), disulfide with human monoclonal ibi306 .kappa. …
Matched Description: … Tafolecimab is under investigation in clinical trial NCT04031742 (A Study to Evaluate Safety and Efficacy ... of IBI306, a PCSK9 Monoclonal Antibody in Chinese Subjects With Homozygous Familial Hypercholesterolemia …
Matched Description: … Tafolecimab is under investigation in clinical trial NCT04031742 (A Study to Evaluate Safety and Efficacy ... of IBI306, a PCSK9 Monoclonal Antibody in Chinese Subjects With Homozygous Familial Hypercholesterolemia …
Velafermin
Velafermin was a novel investigational protein therapeutic, also known as fibroblast growth factor-20 (FGF-20), which promotes both epithelial and mesenchymal cell proliferation in vitro and has demonstrated activity in multiple animal models. Velafermin was investigated as a potential therapy for the prevention and treatment of oral mucositis by fostering the...
Investigational
Matched Synonyms: … RECOMBINANT HUMAN FIBROBLAST GROWTH FACTOR-20 ... FIBROBLAST GROWTH FACTOR 20 (HUMAN RECOMBINANT CG53135) …
Matched Description: … by fostering the regeneration and repair of the cells lining the gastrointestinal tract. ... mesenchymal cell proliferation in vitro and has demonstrated activity in multiple animal models. ... protein therapeutic, also known as fibroblast growth factor-20 (FGF-20), which promotes both epithelial and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … by fostering the regeneration and repair of the cells lining the gastrointestinal tract. ... mesenchymal cell proliferation in vitro and has demonstrated activity in multiple animal models. ... protein therapeutic, also known as fibroblast growth factor-20 (FGF-20), which promotes both epithelial and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Human papillomavirus type 11 L1 capsid protein antigen
Human papillomavirus type 11 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus...
Approved
Matched Synonyms: … L1 protein, Human papillomavirus type 11 Vaccine ... Recombinant human papillomavirus type 11 L1 protein …
Matched Name: … Human papillomavirus type 11 L1 capsid protein antigen …
Matched Description: … by Human Papillomavirus (HPV) types 6, 11, 16 and 18. ... The vaccine is prepared from the purified virus-like particles (VLPs) of the major capsid (L1) protein ... cerevisiae* and self-assembled into VLPs. …
Matched Mixtures name: … GARDASIL® 9 VACUNA RECOMBINANTE NONAVALENTE CONTRA EL VIRUS DEL PAPILOMA HUMANO ... Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
Matched Categories: … Inactivated Human Papillomavirus Vaccine …
Matched Name: … Human papillomavirus type 11 L1 capsid protein antigen …
Matched Description: … by Human Papillomavirus (HPV) types 6, 11, 16 and 18. ... The vaccine is prepared from the purified virus-like particles (VLPs) of the major capsid (L1) protein ... cerevisiae* and self-assembled into VLPs. …
Matched Mixtures name: … GARDASIL® 9 VACUNA RECOMBINANTE NONAVALENTE CONTRA EL VIRUS DEL PAPILOMA HUMANO ... Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
Matched Categories: … Inactivated Human Papillomavirus Vaccine …
Human papillomavirus type 58 L1 capsid protein antigen
Human papillomavirus type 58 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 58. The vaccine is prepared from the purified...
Approved
Matched Synonyms: … L1 protein, Human papillomavirus type 58 Vaccine ... Recombinant human papillomavirus type 58 L1 protein …
Matched Name: … Human papillomavirus type 58 L1 capsid protein antigen …
Matched Description: … It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused ... HPV Type 58 which are produced by separate fermentations in recombinant *Saccharomyces cerevisiae* and ... The vaccine is prepared from the purified virus-like particles (VLPs) of the major capsid (L1) protein …
Matched Mixtures name: … GARDASIL® 9 VACUNA RECOMBINANTE NONAVALENTE CONTRA EL VIRUS DEL PAPILOMA HUMANO ... Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
Matched Name: … Human papillomavirus type 58 L1 capsid protein antigen …
Matched Description: … It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused ... HPV Type 58 which are produced by separate fermentations in recombinant *Saccharomyces cerevisiae* and ... The vaccine is prepared from the purified virus-like particles (VLPs) of the major capsid (L1) protein …
Matched Mixtures name: … GARDASIL® 9 VACUNA RECOMBINANTE NONAVALENTE CONTRA EL VIRUS DEL PAPILOMA HUMANO ... Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
Otlertuzumab
Otlertuzumab is under investigation in clinical trial NCT01188681 (Safety and Efficacy Study of TRU-016 Plus Bendamustine vs. Bendamustine in Relapsed Chronic Lymphocytic Leukemia).
Investigational
Matched Synonyms: … Immunoglobulin, anti-(human cd antigen cd37) (synthetic human-mus musculus fragment tru-016), dimer …
Matched Description: … Otlertuzumab is under investigation in clinical trial NCT01188681 (Safety and Efficacy Study of TRU-016 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Otlertuzumab is under investigation in clinical trial NCT01188681 (Safety and Efficacy Study of TRU-016 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Recombinant methionyl brain-derived neurotrophic factor
Investigational
Matched Synonyms: … Recombinant methionyl human bdnf ... Recombinant methionyl human brain-derived neurotrophic factor …
Fibrinolysin
Fibrinolysin consists of two polypeptide chains, one light and one heavy, linked by a disulfide bond. The light chain has a molecular weight of approximately 27,000 Da and contains the active center of Fibrinolysin; the heavy chain has a molecular weight of approximately 57,000 Da. Fibrinolysin is used as a...
Investigational
Matched Synonyms: … Fibrinolysin, human ... Fibrinolysin (human) …
Matched Description: … Fibrinolysin consists of two polypeptide chains, one light and one heavy, linked by a disulfide bond. ... Fibrinolysin and deoxyribonuclease both act as lytic enzymes. ... The light chain has a molecular weight of approximately 27,000 Da and contains the active center of Fibrinolysin …
Matched Categories: … Blood and Blood Forming Organs ... Enzymes and Coenzymes ... fibrinolysin and desoxyribonuclease …
Matched Description: … Fibrinolysin consists of two polypeptide chains, one light and one heavy, linked by a disulfide bond. ... Fibrinolysin and deoxyribonuclease both act as lytic enzymes. ... The light chain has a molecular weight of approximately 27,000 Da and contains the active center of Fibrinolysin …
Matched Categories: … Blood and Blood Forming Organs ... Enzymes and Coenzymes ... fibrinolysin and desoxyribonuclease …
Lecanemab
Lecanemab is a recombinant humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against aggregated soluble and insoluble forms of amyloid beta (Aβ), which are implicated in the pathophysiology of Alzheimer’s disease. Lecanemab works to reduce Aβ plaques and prevent Aβ deposition in the brain [A253947,A253952] with high selectivity to Aβ...
Approved
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human beta-amyloid protofibril) (human-mus musculus monoclonal BAN2401 heavy ... chain), disulfide with human-mus musculus monoclonal BAN2401 light chain, dimer …
Matched Description: … aggregated soluble and insoluble forms of amyloid beta (Aβ), which are implicated in the pathophysiology ... [L44537] Lecanemab works to reduce Aβ plaques and prevent Aβ deposition in the brain [A253947,A253952 ... Lecanemab is a recombinant humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … aggregated soluble and insoluble forms of amyloid beta (Aβ), which are implicated in the pathophysiology ... [L44537] Lecanemab works to reduce Aβ plaques and prevent Aβ deposition in the brain [A253947,A253952 ... Lecanemab is a recombinant humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Mirvetuximab
Investigational
Matched Synonyms: … (human-mus musculus monoclonal m9346a heavy chain), disulfide with human-mus musculus monoclonal m9346a ... Immunoglobulin g1, anti-(human folate receptor .alpha.) …
Depemokimab
Depemokimab is under investigation in clinical trial NCT05274750 (Efficacy and Safety of Depemokimab (GSK3511294) in Participants With Chronic Rhinosinusitis With Nasal Polyps).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human interleukin 5) (human-mus musculus monoclonal gsk3511294 .gamma.1-chain ... ), disulfide with human-mus musculus monoclonal gsk3511294 .kappa. …
Matched Description: … Depemokimab is under investigation in clinical trial NCT05274750 (Efficacy and Safety of Depemokimab …
Matched Description: … Depemokimab is under investigation in clinical trial NCT05274750 (Efficacy and Safety of Depemokimab …
Tilavonemab
Investigational
Matched Synonyms: … Immunoglobulin g4, anti-(human tau protein) (human-mus musculus monoclonal pr-1649264 .gamma.4-chain) ... , disulfide with human-mus musculus monoclonal pr-1649264 .kappa. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Recombinant Humanized Anti-Tau Antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Recombinant Humanized Anti-Tau Antibody …
Divozilimab
Divozilimab is under investigation in clinical trial NCT05730699 (Efficacy and Safety of Divozilimab in Patients With Neuromyelitis Optica Spectrum Disorders (AQUARELLE)).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human cd20 antigen) (human-mus musculus monoclonal bcd-132 .gamma.1-chain), ... disulfide with human-mus musculus monoclonal bcd-132 .kappa. …
Matched Description: … Divozilimab is under investigation in clinical trial NCT05730699 (Efficacy and Safety of Divozilimab …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Description: … Divozilimab is under investigation in clinical trial NCT05730699 (Efficacy and Safety of Divozilimab …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Displaying drugs 1326 - 1350 of 1780 in total