Human papillomavirus type 11 L1 capsid protein antigen

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Brand Names
Gardasil, Gardasil 9
Generic Name
Human papillomavirus type 11 L1 capsid protein antigen
DrugBank Accession Number
DB10300
Background

Human papillomavirus type 11 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) types 6, 11, 16 and 18. The vaccine is prepared from the purified virus-like particles (VLPs) of the major capsid (L1) protein of HPV Types 6, 11, 16, and 18, which are produced by separate fermentations in recombinant Saccharomyces cerevisiae and self-assembled into VLPs.

Type
Biotech
Groups
Approved
Biologic Classification
Vaccines
Other vaccines
Synonyms
  • L1 protein, Human papillomavirus type 11 Vaccine
  • Recombinant human papillomavirus type 11 L1 protein

Pharmacology

Indication

Not Available

Pharmacology
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Associated Conditions
Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Medicalerrors
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

Products
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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
GardasilHuman papillomavirus type 11 L1 capsid protein antigen (40 mcg / 0.5 mL) + Human papillomavirus type 16 L1 capsid protein antigen (40 mcg / 0.5 mL) + Human papillomavirus type 18 L1 capsid protein antigen (20 mcg / 0.5 mL) + Human papillomavirus type 6 L1 capsid protein antigen (20 mcg / 0.5 mL)SuspensionIntramuscularMerck Ltd.2006-08-162019-08-22Canada flag
GardasilHuman papillomavirus type 11 L1 capsid protein antigen (40 mcg) + Human papillomavirus type 16 L1 capsid protein antigen (40 mcg) + Human papillomavirus type 18 L1 capsid protein antigen (20 mcg) + Human papillomavirus type 6 L1 capsid protein antigen (20 mcg)Injection, suspensionIntramuscularMsd Vaccins2021-03-18Not applicableEU flag
GardasilHuman papillomavirus type 11 L1 capsid protein antigen (40 ug/0.5mL) + Human papillomavirus type 16 L1 capsid protein antigen (40 ug/0.5mL) + Human papillomavirus type 18 L1 capsid protein antigen (20 ug/0.5mL) + Human papillomavirus type 6 L1 capsid protein antigen (20 ug/0.5mL)Injection, suspensionIntramuscularA-S Medication Solutions2006-06-08Not applicableUS flag
GardasilHuman papillomavirus type 11 L1 capsid protein antigen (40 mcg) + Human papillomavirus type 16 L1 capsid protein antigen (40 mcg) + Human papillomavirus type 18 L1 capsid protein antigen (20 mcg) + Human papillomavirus type 6 L1 capsid protein antigen (20 mcg)Injection, suspensionIntramuscularMsd Vaccins2021-03-18Not applicableEU flag
GardasilHuman papillomavirus type 11 L1 capsid protein antigen (40 mcg) + Human papillomavirus type 16 L1 capsid protein antigen (40 mcg) + Human papillomavirus type 18 L1 capsid protein antigen (20 mcg) + Human papillomavirus type 6 L1 capsid protein antigen (20 mcg)Injection, suspensionIntramuscularMsd Vaccins2021-03-18Not applicableEU flag
GardasilHuman papillomavirus type 11 L1 capsid protein antigen (40 mcg) + Human papillomavirus type 16 L1 capsid protein antigen (40 mcg) + Human papillomavirus type 18 L1 capsid protein antigen (20 mcg) + Human papillomavirus type 6 L1 capsid protein antigen (20 mcg)Injection, suspensionIntramuscularMsd Vaccins2021-03-18Not applicableEU flag
GardasilHuman papillomavirus type 11 L1 capsid protein antigen (40 mcg) + Human papillomavirus type 16 L1 capsid protein antigen (40 mcg) + Human papillomavirus type 18 L1 capsid protein antigen (20 mcg) + Human papillomavirus type 6 L1 capsid protein antigen (20 mcg)Injection, suspensionIntramuscularMsd Vaccins2021-03-18Not applicableEU flag
GardasilHuman papillomavirus type 11 L1 capsid protein antigen (40 mcg) + Human papillomavirus type 16 L1 capsid protein antigen (40 mcg) + Human papillomavirus type 18 L1 capsid protein antigen (20 mcg) + Human papillomavirus type 6 L1 capsid protein antigen (20 mcg)Injection, suspensionIntramuscularMsd Vaccins2021-03-18Not applicableEU flag
GardasilHuman papillomavirus type 11 L1 capsid protein antigen (40 ug/0.5mL) + Human papillomavirus type 16 L1 capsid protein antigen (40 ug/0.5mL) + Human papillomavirus type 18 L1 capsid protein antigen (20 ug/0.5mL) + Human papillomavirus type 6 L1 capsid protein antigen (20 ug/0.5mL)Injection, suspensionIntramuscularMerck Sharp & Dohme Corp.2006-06-08Not applicableUS flag
GardasilHuman papillomavirus type 11 L1 capsid protein antigen (40 mcg) + Human papillomavirus type 16 L1 capsid protein antigen (40 mcg) + Human papillomavirus type 18 L1 capsid protein antigen (20 mcg) + Human papillomavirus type 6 L1 capsid protein antigen (20 mcg)Injection, suspensionIntramuscularMsd Vaccins2021-03-18Not applicableEU flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
Z845VHQ61P
CAS number
Not Available

References

General References
Not Available
PubChem Substance
347910486
RxNav
798262

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4Active Not RecruitingPreventionAllogeneic Hematopoietic Stem Cell Transplant Recipient / Hematopoietic and Lymphoid Cell Neoplasm1
4Active Not RecruitingPreventionCervical Cancers / Cervical Precancerous Lesions1
4Active Not RecruitingPreventionHuman Papillomavirus Infections / Human Papillomavirus-Related Cervical Carcinoma1
4Active Not RecruitingPreventionPapillomavirus Infections1
4CompletedHealth Services ResearchCervical Intraepithelial Neoplasia (CIN) / HPV-Related Cervical Carcinoma1
4CompletedOtherCervical Cancers / Hpv / Warts1
4CompletedOtherHealthy Volunteers1
4CompletedPreventionAdenocarcinoma in Situ / Cervical Cancers / Cervical Intraepithelial Neoplasia (CIN)1
4CompletedPreventionAIN / Human Immunodeficiency Virus (HIV) Infections1
4CompletedPreventionCervical Cancers2

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Injection, suspensionIntramuscular
SuspensionIntramuscular
Injection, suspensionIntramuscular; Parenteral
Injection, solutionIntramuscular
Injection
Injection, suspension
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created on December 01, 2015 20:03 / Updated on February 13, 2021 10:52