Displaying drugs 1351 - 1375 of 2016 in total
Retlirafusp alfa
Investigational
Matched Synonyms: … Immunoglobulin G4 (52-glycine, 57-phenylalanine, 227-proline, 233-alanine, 234-alanine, 446-alanine), ... anti-(human programmed death-ligand 1) (human-mus musculus monoclonal SHR-1316 .gamma.4-chain) fusion ... isoform 1), disulfide with (85-glutamic acid) human-mus musculus monoclonal SHR-1316 .kappa. …
Matched Categories: … Recombinant Proteins ... Amino Acids, Peptides, and Proteins …
Matched Categories: … Recombinant Proteins ... Amino Acids, Peptides, and Proteins …
Posoleucel
Investigational
Matched Synonyms: … -6, Epstein Barr virus, and adenovirus ... Allogeneic multi-virus specific T lymphocytes targeting BK virus, cytomegalovirus, human herpes virus …
Narsoplimab
Thrombotic microangiopathies (TMA), including thrombotic thrombocytopenic purpura and atypical hemolytic uremic syndrome, are associated with injury and dysregulation of microvascular endothelium and platelets. Evidence increasingly points to a role for the complement system in TMA.[A241030, A241040] Mannan-associated lectin-binding serine protease-2 (MASP-2) is a major effector in the complement lectin pathway.[A241030,...
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4 (226-PROLINE), ANTI-(HUMAN MANNAN-BINDING LECTIN-ASSOCIATED SERINE PROTEASE 2) (HUMAN ... IMMUNOGLOBULIN G4-LAMBDA, ANTI-(HOMO SAPIENS MANNAN-BINDING LECTIN SERINE PROTEASE 2 (MANNOSE-BINDING ... MONOCLONAL OMS721 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL OMS721 .LAMBDA. …
Matched Description: … [A241030, A241040] Narsoplimab (OMS721), a human IgG4λ anti-MASP-2 antibody, is under consideration as ... uremic syndrome, are associated with injury and dysregulation of microvascular endothelium and platelets ... Thrombotic microangiopathies (TMA), including thrombotic thrombocytopenic purpura and atypical hemolytic …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … [A241030, A241040] Narsoplimab (OMS721), a human IgG4λ anti-MASP-2 antibody, is under consideration as ... uremic syndrome, are associated with injury and dysregulation of microvascular endothelium and platelets ... Thrombotic microangiopathies (TMA), including thrombotic thrombocytopenic purpura and atypical hemolytic …
Matched Categories: … Amino Acids, Peptides, and Proteins …
C-peptide
C-peptide is under investigation in clinical trial NCT00278980 (Effect of C-peptide on Diabetic Peripheral Neuropathy).
Investigational
Matched Synonyms: … Human c-peptide ... Human proinsulin c-peptide ... Proinsulin c-peptide (human) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Lilotomab
Lilotomab is under investigation in clinical trial NCT01796171 (A Phase 1/2 Study of Betalutin for Treatment of Relapsed Non-hodgkin Lymphoma).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human cd antigen cd37) (mus musculus monoclonal hh1 heavy chain), disulfide …
Glenzocimab
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human platetet glycoprotein vi) fab fragment (humanized monoclonal act017 .gamma …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Beludavimab
Beludavimab is under investigation in clinical trial NCT04746183 (AGILE (Early Phase Platform Trial for COVID-19)).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1 (246-ALANINE,340-LEUCINE,342-GLUTAMIC ACID,438-LEUCINE,444-SERINE), ANTI-(SEVERE ACUTE ... -7832 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOC ... RESPIRATORY SYNDROME CORONAVIRUS 2 SPIKE GLYCOPROTEIN RECEPTOR-BINDING DOMAIN) (HUMAN MONOCLONAL VIR …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Gebasaxturev
Investigational
Matched Synonyms: … Human coxsackievirus A21 ... Enterovirus human enterovirus C serogroup coxsackievirus serotype A21 …
Palucorcel
Palucorcel is an investigational stem cell therapy consisting of human umbilical tissue-derived cells. Developed by Janssen Biotech, it is being investigated for the treatment of various conditions such as amyotrophic lateral sclerosis (ALS) and macular degeneration.
Investigational
Matched Synonyms: … Human umbilical tissue-derived cells ... HUMAN UMBILICAL TISSUE-DERIVED CELLS (ALLOGENIC) …
Matched Description: … Palucorcel is an investigational stem cell therapy consisting of human umbilical tissue-derived cells ... being investigated for the treatment of various conditions such as amyotrophic lateral sclerosis (ALS) and …
Matched Description: … Palucorcel is an investigational stem cell therapy consisting of human umbilical tissue-derived cells ... being investigated for the treatment of various conditions such as amyotrophic lateral sclerosis (ALS) and …
OTL-102
OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human gp91phox gene. It is being investigated for the treatment of X-linked chronic granulomatous disease.
Investigational
Matched Synonyms: … ex vivo using a lentiviral vector encoding the human gp91phox gene ... Autologous CD34+ enriched cell population that contains hematopoietic stem and progenitor cells transduced …
Matched Description: … transduced ex vivo using a lentiviral vector encoding the human gp91phox gene. ... OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells …
Matched Description: … transduced ex vivo using a lentiviral vector encoding the human gp91phox gene. ... OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells …
PEP0101
PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) designed to down-regulate the expression of EVI1 oncogene in cancer cells.
Investigational
Matched Synonyms: … factor and an elastin-like polypeptide drug carrier. ... Nanocomplex consisting of a small interfering RNA that targets the human EV11 oncogenic transcription …
Matched Description: … PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) …
Matched Description: … PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) …
EI-001
Investigational
Matched Synonyms: … Human monoclonal antibody based on an IgG1 lambda framework against human interferon gamma …
Barzolvolimab
Barzolvolimab is under investigation in clinical trial NCT06455202 (A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria (CSU)).
Investigational
Matched Synonyms: … ,de-C-terminal-lysine], anti-(human receptor tyrosine kinase KIT extracellular domain) (human-Mus musculus ... Immunoglobulin G1 [233-alanine,234-glutamine,251-tyrosine,253-threonine,255-glutamic acid,321-glutamine …
Licaminlimab
Licaminlimab is under investigation in clinical trial NCT05896670 (Safety and Efficacy of Licaminlimab Ophthalmic Suspension for the Treatment of Dry Eye Disease).
Investigational
Matched Synonyms: … Immunoglobulin, anti-(human tumor necrosis factor α)(human-Oryctolagus cuniculus monoclonal ESBA1622 ... immunoglobulin scFv, anti-[Homo sapiens TNF (tumor necrosis factor, TNFSF2, DIF, TNF-alpha)], humanized …
Matched Description: … Licaminlimab is under investigation in clinical trial NCT05896670 (Safety and Efficacy of Licaminlimab …
Matched Description: … Licaminlimab is under investigation in clinical trial NCT05896670 (Safety and Efficacy of Licaminlimab …
Efocipegtrutide
Efocipegtrutide is a long-acting, monomeric peptide triple agonist.
Investigational
Matched Synonyms: … GLUCAGON ANALOG CONJUGATED WITH HUMAN IMMUNOGLOBULIN G4 FRAGMENT ... IMMUNOGLOBULIN G4 (HUMAN .GAMMA.4-CHAIN C REGION C-TERMINAL FRAGMENT), DIMER, 1-(1-(3-HYDROXYPROPYL)- …
Respigam
Investigational
Matched Synonyms: … Respiratory syncytial virus immune globulin intravenous (human) …
Matched Categories: … Immunoglobulin G ... Amino Acids, Peptides, and Proteins ... Immunoglobulin Isotypes …
Matched Categories: … Immunoglobulin G ... Amino Acids, Peptides, and Proteins ... Immunoglobulin Isotypes …
ARGX-119
ARGX-119 is a monoclonal antibody that targets and activates muscle-specific kinase (MuSK).
Investigational
Matched Synonyms: … targets and activates MuSK ... a fully humanized immunoglobulin gamma 1 (IgG1) agonistic monoclonal antibody (mAb) that specifically …
Matched Description: … ARGX-119 is a monoclonal antibody that targets and activates muscle-specific kinase (MuSK). …
Matched Description: … ARGX-119 is a monoclonal antibody that targets and activates muscle-specific kinase (MuSK). …
Etevritamab
Investigational
Matched Synonyms: … IMMUNOGLOBULIN, BISPECIFIC, ANTI-(HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR VARIANT III) (HUMAN MONOCLONAL ... KINASE ERBB-1, ERBB1, HER1, HER-1, ERBB) VARIANT III (EGFRVIII)) AND ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON ... IMMUNOGLOBULIN SCFV-SCFV, ANTI-(HOMO SAPIENS EGFR (EPIDERMAL GROWTH FACTOR RECEPTOR, RECEPTOR TYROSINE-PROTEIN …
Thymalfasin
Thymalfasin is a chemically synthesized version of thymosin alpha 1 that is identical to human thymosin alpha 1. Thymosin alpha 1 is an acetylated polypeptide. Thymosin alpha 1 is now approved in 35 developing countries for the treatment of Hepatitis B and C. It is also used to boost the...
Investigational
Matched Synonyms: … Thymosin alpha1 (human) …
Matched Description: … Thymalfasin is a chemically synthesized version of thymosin alpha 1 that is identical to human thymosin ... Thymosin alpha 1 is now approved in 35 developing countries for the treatment of Hepatitis B and C. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … Thymalfasin is a chemically synthesized version of thymosin alpha 1 that is identical to human thymosin ... Thymosin alpha 1 is now approved in 35 developing countries for the treatment of Hepatitis B and C. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Botaretigene sparoparvovec
Investigational
Matched Synonyms: … DNA (RECOMBINANT PSEUDOTYPED ADENO-ASSOCIATED VIRUS 5 VECTOR AAV-RPGR HUMAN RHODOPSIN KINASE PROMOTER ... FRAGMENT-REGULATED HUMAN RETINITIS PIGMENTOSA GTPASE REGULATOR RPGR-ORF15 ISOFORM GENE VARIANT PLUS …
Inolimomab
Inolimomab is under investigation as an agent to treat steroid-resistant graft vs host disease. It has thus far offered similar efficacy to other monoclonal antibody options, though it may carry a higher risk of infections.
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human interleukin 2 receptor alpha-chain) (mouse monoclonal B-B10 gammal-chain …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Plutavimab
Plutavimab is under investigation in clinical trial NCT04900428 (Study to Evaluate a Single Intranasal Dose of STI-2099 (COVI-DROPS™) in Outpatient Adults With COVID-19 (UK)).
Investigational
Matched Synonyms: … glycoprotein receptor-binding domain) (human monoclonal sti-2020 .gamma.1-chain), disulfide with human ... Immunoglobulin g1 (234-alanine,235-alanine), anti-(severe acute respiratory syndrome coronavirus 2 spike …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Endothelin-1
Endothelin 1 is under investigation in clinical trial NCT00745693 (The Effects of Diesel Exhaust Inhalation on Vascular Function - the Role of Endothelin).
Investigational
Matched Synonyms: … Human endothelin ... Endothelin 1 (human) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Efzofitimod
Efzofitimod (ATYR1923) is a fusion protein comprised of the immuno-modulatory domain of histidyl tRNA synthetase fused to the FC region of a human antibody. It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response in inflammatory disease states.
Investigational
Matched Synonyms: … Human IgG1Fc- iMod domain (amino acids 2-60) of human HARS fusion protein …
Matched Description: … It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response ... protein comprised of the immuno-modulatory domain of histidyl tRNA synthetase fused to the FC region of a human …
Matched Description: … It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response ... protein comprised of the immuno-modulatory domain of histidyl tRNA synthetase fused to the FC region of a human …
Vanglusagene ensiparvovec
Investigational
Matched Synonyms: … and a codon-optimized expression cassette to drive expression of a secretable form of human acid a-glucosidase ... recombinant adeno-associated viral (AAV) vector that contains a bio-engineered capsid (AAV-Spark100) …
Displaying drugs 1351 - 1375 of 2016 in total