Displaying drugs 1401 - 1425 of 1560 in total
N,N'-DIPHENYLPYRAZOLO[1,5-A][1,3,5]TRIAZINE-2,4-DIAMINE
Experimental
Matched Name: … N,N'-DIPHENYLPYRAZOLO[1,5-A][1,3,5]TRIAZINE-2,4-DIAMINE …
Matched Iupac: … N2,N4-diphenylpyrazolo[1,5-a][1,3,5]triazine-2,4-diamine …
Matched Iupac: … N2,N4-diphenylpyrazolo[1,5-a][1,3,5]triazine-2,4-diamine …
(5-Chloropyrazolo[1,5-a]Pyrimidin-7-Yl)-(4-Methanesulfonylphenyl)Amine
Experimental
Matched Name: … (5-Chloropyrazolo[1,5-a]Pyrimidin-7-Yl)-(4-Methanesulfonylphenyl)Amine …
Matched Iupac: … 5-chloro-N-(4-methanesulfonylphenyl)pyrazolo[1,5-a]pyrimidin-7-amine …
Matched Iupac: … 5-chloro-N-(4-methanesulfonylphenyl)pyrazolo[1,5-a]pyrimidin-7-amine …
N-(2-chlorophenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine
Experimental
Matched Name: … N-(2-chlorophenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine …
Matched Iupac: … N-(2-chlorophenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine …
Matched Iupac: … N-(2-chlorophenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine …
N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE
Experimental
Matched Name: … N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE …
Matched Iupac: … (2S)-1-[(8aR)-octahydropyrrolo[1,2-a]pyrimidin-1-yl]-4-methylpentan-2-amine …
Matched Iupac: … (2S)-1-[(8aR)-octahydropyrrolo[1,2-a]pyrimidin-1-yl]-4-methylpentan-2-amine …
Ketoconazole
Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections.[FDA Label] It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity and preventing growth of the fungus.[A181802,T116] Ketoconazole was first approved in an oral formulation...
Approved
Investigational
Matched Description: … Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal ... ] and [clotrimazole], due to its broad spectrum and good absorption. ... synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity and …
Matched Categories: … Sex Hormones and Insulins ... Imidazole and Triazole Derivatives ... Gynecological Antiinfectives and Antiseptics ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … Nizoral A-D ... A-BE LOTION ... APO-KECO …
Matched Categories: … Sex Hormones and Insulins ... Imidazole and Triazole Derivatives ... Gynecological Antiinfectives and Antiseptics ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … Nizoral A-D ... A-BE LOTION ... APO-KECO …
Exagamglogene autotemcel
Sickle cell disease (SCD) is a genetic disorder characterized by the production of abnormal sickle-shaped red blood cells (called hemoglobin S, HbS) that initiate a pathophysiology resulting in severe pain, progressive multi-organ damage, and premature death. Treatment options for SCD are largely focused on preventing the production and circulation of...
Approved
Investigational
Matched Synonyms: … interspaced short palindromic repeats/CRISPR-associated protein 9) mediated gene editing consisting of a …
Matched Description: … cells which has been investigated in clinical trials for the treatment of severe SCD and severe beta-thalassemia ... ] - a mainstay of treatment since the 1990s - as well as newer agents like [crizanlizumab] and [voxelotor ... [L10139] Following engraftment, it causes an increase in the production of HbF and a subsequent decrease …
Matched Categories: … Blood and Blood Forming Organs …
Matched Description: … cells which has been investigated in clinical trials for the treatment of severe SCD and severe beta-thalassemia ... ] - a mainstay of treatment since the 1990s - as well as newer agents like [crizanlizumab] and [voxelotor ... [L10139] Following engraftment, it causes an increase in the production of HbF and a subsequent decrease …
Matched Categories: … Blood and Blood Forming Organs …
Ivonescimab
Ivonescimab is under investigation in clinical trial NCT05184712 (Phase 3 Clinical Study of AK112 for NSCLC Patients).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1 (240-ALANINE,241-ALANINE), ANTI-(HUMAN VASCULAR ENDOTHELIAL GROWTH FACTOR A) (HUMAN-MUS …
Pemetrexed
Pemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the brand name Alimta. It is indicated for use in combination with cisplatin for the treatment of patients with malignant pleural mesothelioma whose disease is either unresectable or who are otherwise not candidates for...
Approved
Investigational
Matched Description: … Pemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the ... Its use in non-small cell lung cancer has also been investigated. ... treatment of patients with malignant pleural mesothelioma whose disease is either unresectable or who are …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index ... Drugs that are Mainly Renally Excreted ... OAT3/SLC22A8 Substrates with a Narrow Therapeutic Index …
Matched Products: … Act Pemetrexed ... DBL PEMETREXED (AS DISODIUM) POWDER FOR INJECTON ... NEXTREXED 500 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index ... Drugs that are Mainly Renally Excreted ... OAT3/SLC22A8 Substrates with a Narrow Therapeutic Index …
Matched Products: … Act Pemetrexed ... DBL PEMETREXED (AS DISODIUM) POWDER FOR INJECTON ... NEXTREXED 500 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE …
Mupirocin
Mupirocin, formerly termed pseudomonic acid A, is a novel antibacterial agent with a unique chemical structure and mode of action apart from other antibiotic agents. Produced by fermentation using the organism Pseudomonas fluorescens, mupirocin is a naturally-occurring antibiotic that displays a broad-specturm activity against many gram-positive bacteria and certain gram-negative...
Approved
Investigational
Vet approved
Matched Synonyms: … Pseudomonic acid A …
Matched Description: … and traumatic skin lesions due to secondary skin infections caused by _S. aureus_ and _S. pyogenes_. ... antibiotic that displays a broad-specturm activity against many gram-positive bacteria and certain gram-negative ... chemical structure and mode of action apart from other antibiotic agents. …
Matched Mixtures name: … Pre and Post Sx Pouch …
Matched Products: … Centany AT ... MUPIDERM UNGUENTO AL 2% …
Matched Description: … and traumatic skin lesions due to secondary skin infections caused by _S. aureus_ and _S. pyogenes_. ... antibiotic that displays a broad-specturm activity against many gram-positive bacteria and certain gram-negative ... chemical structure and mode of action apart from other antibiotic agents. …
Matched Mixtures name: … Pre and Post Sx Pouch …
Matched Products: … Centany AT ... MUPIDERM UNGUENTO AL 2% …
Etoposide
A semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division,...
Approved
Matched Description: … Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. ... Etoposide acts primarily in the G2 and S phases of the cell cycle. ... This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... UGT1A1 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic Index …
Matched Products: … N/A …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... UGT1A1 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic Index …
Matched Products: … N/A …
Azapropazone
Withdrawn
Matched Synonyms: … 5-(Dimethylamino)-9-methyl-2-propyl-1H-pyrazolo(1,2-a)(1,2,4)benzotriazine-1,3(2H)-dione …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Daptomycin
Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and -resistant Staphylococcus aureus (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE).[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked...
Approved
Investigational
Matched Description: … bacteria, including methicillin-susceptible and -resistant _Staphylococcus aureus_ (MSSA/MRSA) and vancomycin-resistant ... D-amino acids, with the C-terminal 10 amino acids forming an ester-linked ring and the N-terminal tryptophan ... A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Drugs that are Mainly Renally Excreted …
Matched Products: … CUBICIN® 350 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Drugs that are Mainly Renally Excreted …
Matched Products: … CUBICIN® 350 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …
Fosbretabulin
Fosbretabulin has been investigated for the treatment of Anaplastic Thyroid Cancer.
Investigational
Matched Synonyms: … Combretastatin A4 phosphate ... Combretastatin A-4 phosphate …
Matched Description: … Fosbretabulin has been investigated for the treatment of Anaplastic Thyroid Cancer. …
Matched Description: … Fosbretabulin has been investigated for the treatment of Anaplastic Thyroid Cancer. …
Aphidicolin
Aphidicolin is an antimitotic and antiviral metabolite of the mould Cephalosporium aphidicola. It inhibits DNA polymerase alpha and blocks DNA replication.[A259157, A259162]
Investigational
Matched Synonyms: … 8,11a-methano-11ah-cyclohepta(a)naphthalene-4,9-dimethanol, tetradecahydro-3,9-dihydroxy-4,11b-dimethyl …
Matched Description: … Aphidicolin is an antimitotic and antiviral metabolite of the mould _Cephalosporium aphidicola_. ... It inhibits DNA polymerase alpha and blocks DNA replication.[A259157, A259162] …
Matched Description: … Aphidicolin is an antimitotic and antiviral metabolite of the mould _Cephalosporium aphidicola_. ... It inhibits DNA polymerase alpha and blocks DNA replication.[A259157, A259162] …
Schisandra chinensis fruit
Schisandra chinensis fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Five-flavoured Seed …
Matched Description: … It is not an approved drug. ... Schisandra chinensis fruit is a plant/plant extract used in some OTC (over-the-counter) products. …
Matched Description: … It is not an approved drug. ... Schisandra chinensis fruit is a plant/plant extract used in some OTC (over-the-counter) products. …
Ipratropium
Ipratropium is a quaternary ammonium derivative of atropine that acts as an anticholinergic agent. It is commonly administered through inhalation which allows producing a local effect without presenting a significant systemic absorption. Ipratropium as a therapeutic agent was developed by Boehringer Ingelheim and its first monotherapy product was FDA approved...
Approved
Experimental
Matched Description: … [A176957]
Ipratropium as a therapeutic agent was developed by Boehringer Ingelheim and its first monotherapy ... product was FDA approved in 1986, while the combination product of ipratropium and [albuterol] was approved ... Ipratropium is a quaternary ammonium derivative of [atropine][A176957] that acts as an anticholinergic …
Matched Mixtures name: … Ipratropium Bromide and Albuterol Sulfate ... Ipratropium Bromide and Albuterol Sulfate ... Ipratropium Bromide and Albuterol Sulfate …
Matched Categories: … fenoterol and ipratropium bromide ... salbutamol and ipratropium bromide ... Aza Compounds …
Matched Products: … Aa-ipravent ... A-TROFINSA ... Apo-ipravent Sterules …
Matched Mixtures name: … Ipratropium Bromide and Albuterol Sulfate ... Ipratropium Bromide and Albuterol Sulfate ... Ipratropium Bromide and Albuterol Sulfate …
Matched Categories: … fenoterol and ipratropium bromide ... salbutamol and ipratropium bromide ... Aza Compounds …
Matched Products: … Aa-ipravent ... A-TROFINSA ... Apo-ipravent Sterules …
Methylprednisolone hemisuccinate
A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.
Approved
Matched Iupac: … )-1,10-dihydroxy-5,9a,11a-trimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Compounds used in a research, industrial, or household setting …
Matched Products: … A-methapred …
Matched Description: … A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Compounds used in a research, industrial, or household setting …
Matched Products: … A-methapred …
(3s,8ar)-3-(4-Hydroxybenzyl)Hexahydropyrrolo[1,2-a]Pyrazine-1,4-Dione
Experimental
Matched Name: … (3s,8ar)-3-(4-Hydroxybenzyl)Hexahydropyrrolo[1,2-a]Pyrazine-1,4-Dione …
Matched Iupac: … (3S,8aS)-3-[(4-hydroxyphenyl)methyl]-octahydropyrrolo[1,2-a]pyrazine-1,4-dione …
Matched Iupac: … (3S,8aS)-3-[(4-hydroxyphenyl)methyl]-octahydropyrrolo[1,2-a]pyrazine-1,4-dione …
3'-O-N-Octanoyl-a-D-Glucopyranosyl-B-D-Fructofuranoside
Experimental
Matched Name: … 3'-O-N-Octanoyl-a-D-Glucopyranosyl-B-D-Fructofuranoside …
1,3-DI(N-Propyloxy-A-mannopyranosyl)-carbomyl 5-methyazido-benzene
Experimental
Matched Name: … 1,3-DI(N-Propyloxy-A-mannopyranosyl)-carbomyl 5-methyazido-benzene …
1,3,4-TRIHYDROXY-5-(3-PHENOXYPROPYL)-CYCLOHEXANE-1-CARBOXYLIC A CID
Experimental
Matched Name: … 1,3,4-TRIHYDROXY-5-(3-PHENOXYPROPYL)-CYCLOHEXANE-1-CARBOXYLIC A CID …
N-(2,6-dimethylphenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine
Experimental
Matched Name: … N-(2,6-dimethylphenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine …
Matched Iupac: … N-(2,6-dimethylphenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine …
Matched Iupac: … N-(2,6-dimethylphenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine …
Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen
Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a vaccine.
Approved
Matched Name: … Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen …
Matched Description: … a vaccine. ... Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen is …
Matched Description: … a vaccine. ... Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen is …
Beclomethasone dipropionate
Beclomethasone dipropionate is a second-generation synthetic corticosteroid and diester of beclomethasone, which is structurally similar to dexamethasone. It is a prodrug of an active metabolite beclomethasone 17-monopropionate (17-BMP) which acts on the glucocorticoid receptor to mediates its therapeutic action. Beclomethasone dipropionate itself posesses weak glucocorticoid receptor binding affinity and is...
Approved
Investigational
Matched International brands: … Clenil-A …
Matched Iupac: … 2,9a,11a-trimethyl-7-oxo-1-(propanoyloxy)-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … later in a dry powder inhaler and an aqueous nasal spray. ... Beclomethasone dipropionate is a second-generation[A179842] synthetic corticosteroid and diester of beclomethasone ... Beclomethasone dipropionate became first available in a pressurized metered-dose inhaler in 1972 and …
Matched Mixtures name: … Ibicar S (Salbutamol 100 mcg/actuation and Beclometasone 50 mcg/actuation) Pressurised Inhalation …
Matched Categories: … Alimentary Tract and Metabolism ... formoterol and beclometasone ... salbutamol and beclometasone ... beclometasone and antibiotics ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Beconase AQ Nasal Aem 50mcg/aem ... Beclovent Aem 50mcg/aem ... Beclovent - Aem 50mcg/aem …
Matched Iupac: … 2,9a,11a-trimethyl-7-oxo-1-(propanoyloxy)-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … later in a dry powder inhaler and an aqueous nasal spray. ... Beclomethasone dipropionate is a second-generation[A179842] synthetic corticosteroid and diester of beclomethasone ... Beclomethasone dipropionate became first available in a pressurized metered-dose inhaler in 1972 and …
Matched Mixtures name: … Ibicar S (Salbutamol 100 mcg/actuation and Beclometasone 50 mcg/actuation) Pressurised Inhalation …
Matched Categories: … Alimentary Tract and Metabolism ... formoterol and beclometasone ... salbutamol and beclometasone ... beclometasone and antibiotics ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Beconase AQ Nasal Aem 50mcg/aem ... Beclovent Aem 50mcg/aem ... Beclovent - Aem 50mcg/aem …
TG01 vaccine
Investigational
Matched Synonyms: … 12-A-p21 RAS(5-21). 12-C-p21 RAS(5-21). 12-D-p21 RAS(5-21). 12-Rp21 RAS(5-21). 12-S-p21 RAS(5-21). 12 …
Displaying drugs 1401 - 1425 of 1560 in total