Displaying drugs 14226 - 14250 of 14813 in total
Ispectamab debotansine
Ispectamab debotansine is an antibody drug conjugate comprised of an anti-B cell maturation (BCMA) IgG1 humanized antibody conjugated covalently to the dibenzocyclooctyne (DBCO) noncleavable linker maytansinoid warhead.
Investigational
Matched Description: … Ispectamab debotansine is an antibody drug conjugate comprised of an anti-B cell maturation (BCMA) IgG1 ... humanized antibody conjugated covalently to the dibenzocyclooctyne (DBCO) noncleavable linker maytansinoid …
Cambinol
Cambinol is a beta-naphtol derivative that inhibits NAD-dependant deacetylases to reduce cell survival under stress. This activity is currently being investigated for its use as a cancer treatment.
Experimental
Matched Iupac: … 5-[(2-hydroxynaphthalen-1-yl)methyl]-6-phenyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one …
Matched Description: … This activity is currently being investigated for its use as a cancer treatment. ... Cambinol is a beta-naphtol derivative that inhibits NAD-dependant deacetylases to reduce cell survival …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … This activity is currently being investigated for its use as a cancer treatment. ... Cambinol is a beta-naphtol derivative that inhibits NAD-dependant deacetylases to reduce cell survival …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Opicinumab
Opicinumab is under investigation in clinical trial NCT02641041 (Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of BIIB033 in Healthy Japanese Participants).
Investigational
Matched Description: … of Single and Multiple Doses of BIIB033 in Healthy Japanese Participants). ... Opicinumab is under investigation in clinical trial NCT02641041 (Safety, Tolerability, and Pharmacokinetics …
2',3'-Dideoxyadenosine triphosphate
Experimental
Crocin
Crocin has been investigated for the treatment of Hyperglycemia, Metabolic Syndrome, Hypertriglyceridemia, and Hypercholesterolemia.
Investigational
Matched Description: … Crocin has been investigated for the treatment of Hyperglycemia, Metabolic Syndrome, Hypertriglyceridemia …
Ricolinostat
Ricolinostat is under investigation for the treatment of Breast Carcinoma and Metastatic Breast Cancer.
Investigational
Matched Description: … Ricolinostat is under investigation for the treatment of Breast Carcinoma and Metastatic Breast Cancer …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Rotigaptide
Rotigaptide is under investigation for the basic science of Heart Disease and Vascular Disease.
Investigational
Matched Iupac: … (2R)-N-(carbamoylmethyl)-2-(2-{[(2R,4S)-1-[(2R)-1-[(2R)-2-acetamido-3-(4-hydroxyphenyl)propanoyl]pyrrolidine …
Matched Description: … Rotigaptide is under investigation for the basic science of Heart Disease and Vascular Disease. …
Matched Description: … Rotigaptide is under investigation for the basic science of Heart Disease and Vascular Disease. …
PF-06821497
PF-06821497 is under investigation in clinical trial NCT03460977 (PF-06821497 Treatment Of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma).
Investigational
Matched Iupac: … )methyl]-2-[(4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-1,2,3,4-tetrahydroisoquinolin-1- …
Matched Description: … PF-06821497 is under investigation in clinical trial NCT03460977 (PF-06821497 Treatment Of Relapsed/Refractory …
Matched Description: … PF-06821497 is under investigation in clinical trial NCT03460977 (PF-06821497 Treatment Of Relapsed/Refractory …
N-(3-carboxypropanoyl)-L-norvaline
N-(3-carboxypropanoyl)-L-norvaline is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at his terminal nitrogen atom. This medication is known to target n-acetylornithine carbamoyltransferase and putative ornithine carbamoyltransferase.
Experimental
Matched Description: … N-(3-carboxypropanoyl)-L-norvaline is a solid. ... This compound belongs to the n-acyl-alpha amino acids. …
Luvadaxistat
Luvadaxistat is under investigation in clinical trial NCT03214588 (Efficacy, Tolerability, and Pharmacokinetics of Multiple Doses of Oral TAK-831 in Adults With Friedreich Ataxia).
Investigational
Matched Description: … of Multiple Doses of Oral TAK-831 in Adults With Friedreich Ataxia). ... Luvadaxistat is under investigation in clinical trial NCT03214588 (Efficacy, Tolerability, and Pharmacokinetics …
GW 597599
GW 597599, a neurokinin-1 (NK1) receptor antagonist is currently in phase II trials for chemotherapy-induced vomiting; functional dyspepsia; depression and anxiety.
Investigational
Matched Description: … GW 597599, a neurokinin-1 (NK1) receptor antagonist is currently in phase II trials for chemotherapy-induced …
Talaporfin
Talaporfin has been investigated for the treatment of Port-Wine Stain and Benign Prostatic Hyperplasia.
Investigational
Matched Iupac: … {8,11}.1^{13,16}]tetracosa-1,3(24),6,8,10,12,14,16(22),17,19-decaen-2-yl]acetamido}butanedioic acid ... carboxyethyl)-10-ethenyl-15-ethyl-5,9,14,19-tetramethyl-21,22,23,24-tetraazapentacyclo[16.2.1.1^{3,6}.1^ …
Matched Description: … Talaporfin has been investigated for the treatment of Port-Wine Stain and Benign Prostatic Hyperplasia …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Talaporfin has been investigated for the treatment of Port-Wine Stain and Benign Prostatic Hyperplasia …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Vibostolimab
Vibostolimab is under investigation in clinical trial NCT04303169 (Substudy 02C: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents or Pembrolizumab Alone in Participants With Stage III Melanoma Who Are Candidates for Neoadjuvant Therapy (MK-3475-02C/KEYMAKER-U02)).
Investigational
Matched Description: … of Pembrolizumab in Combination With Investigational Agents or Pembrolizumab Alone in Participants With ... Vibostolimab is under investigation in clinical trial NCT04303169 (Substudy 02C: Safety and Efficacy …
Setrusumab
Setrusumab is under investigation in clinical trial NCT01406548 (Safety and Efficacy of Multiple Dosing Regimens of BPS804 in Post Menopausal Women With Low Bone Mineral Density).
Investigational
Matched Description: … Regimens of BPS804 in Post Menopausal Women With Low Bone Mineral Density). ... Setrusumab is under investigation in clinical trial NCT01406548 (Safety and Efficacy of Multiple Dosing …
Dubermatinib
Dubermatinib is under investigation in clinical trial NCT03572634 (Phase 1/2 Study of TP-0903 (an Inhibitor of AXL Kinase) in Patients With Previously Treated CLL).
Investigational
Matched Iupac: … -1-sulfonamide ... 2-{[5-chloro-2-({4-[(4-methylpiperazin-1-yl)methyl]phenyl}amino)pyrimidin-4-yl]amino}-N,N-dimethylbenzene …
Matched Description: … Dubermatinib is under investigation in clinical trial NCT03572634 (Phase 1/2 Study of TP-0903 (an Inhibitor ... of AXL Kinase) in Patients With Previously Treated CLL). …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Dubermatinib is under investigation in clinical trial NCT03572634 (Phase 1/2 Study of TP-0903 (an Inhibitor ... of AXL Kinase) in Patients With Previously Treated CLL). …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Milciclib Maleate
Milciclib Maleate is under investigation in clinical trial NCT01301391 (Study of Oral PHA-848125AC in Patients With Malignant Thymoma Previously Treated With Multiple Lines of Chemotherapy).
Investigational
Matched Iupac: … N,1,4,4-tetramethyl-8-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-1H,4H,5H-pyrazolo[4,3-h]quinazoline-3 …
Matched Description: … Milciclib Maleate is under investigation in clinical trial NCT01301391 (Study of Oral PHA-848125AC in ... Patients With Malignant Thymoma Previously Treated With Multiple Lines of Chemotherapy). …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Milciclib Maleate is under investigation in clinical trial NCT01301391 (Study of Oral PHA-848125AC in ... Patients With Malignant Thymoma Previously Treated With Multiple Lines of Chemotherapy). …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Pegcantratinib
Pegcantratinib is under investigation in clinical trial NCT03448081 (Safety, Tolerability and Efficacy of SNA-120 for Treatment of Pruritus and Psoriasis in Subjects Treated With Calcipotriene).
Investigational
Matched Description: … of SNA-120 for Treatment of Pruritus and Psoriasis in Subjects Treated With Calcipotriene). ... Pegcantratinib is under investigation in clinical trial NCT03448081 (Safety, Tolerability and Efficacy …
Displaying drugs 14226 - 14250 of 14813 in total