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Displaying drugs 1426 - 1450 of 1940 in total
Eflepedocokin alfa is a recombinant IL-22-Fc fusion protein manufactured in Chinese hamster ovary cells that is composed of 2 human interleukin 22 (IL-22) molecules linked to an immunoglobulin constant region (IgG2-Fc).[A225706, L27661] It is being developed by Evive Biotech (previously known as Generon BioMed Inc).
Investigational
Matched Synonyms: … IL-22 fusion protein ... F-652 (RECOMBINANT FUSION PROTEIN CONSISTING OF TWO HUMAN INTERLEUKIN-22 (IL-22) MOLECULES LINKED TO …
Matched Description: … Eflepedocokin alfa is a recombinant IL-22-Fc fusion protein manufactured in Chinese hamster ovary cells …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Proteins ... Recombinant Proteins
Iodamide is a contrast medium molecule that is no longer marketed in the United States.
Withdrawn
Matched Products: … UROMIRO 300 SODICO
Efzofitimod (ATYR1923) is a fusion protein comprised of the immuno-modulatory domain of histidyl tRNA synthetase fused to the FC region of a human antibody. It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response in inflammatory disease states.
Investigational
Matched Synonyms: … Human IgG1Fc- iMod domain (amino acids 2-60) of human HARS fusion protein
Matched Description: … It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response ... Efzofitimod (ATYR1923) is a fusion protein comprised of the immuno-modulatory domain of histidyl tRNA …
Investigational
Matched Synonyms: … Human single domain antibody-like protein inhibitor of the chemokine receptor type 4 …
Investigational
Matched Synonyms: … chlorophenyl)-5-hydroxy-8-((3S,4R)-3-hydroxy-1-methylpiperidin-4-yl)-4-oxo-4H-chromen-7-yl dihydrogen phosphate
A component of phosphatidylcholines (lecithins), in which the two hydroxy groups of glycerol are esterified with fatty acids. (From Stedman, 26th ed) It counteracts the effects of urea on enzymes and other macromolecules. [PubChem]
Experimental
Investigational
Matched Synonyms: … (2R)-2,3-dihydroxypropyl 2-(trimethylammonio)ethyl phosphate
Matched Description: … (From Stedman, 26th ed) It counteracts the effects of urea on enzymes and other macromolecules. …
Dasabuvir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Matched Synonyms: … Sodium 3-(3-tert-butyl-4-methoxy-5-{6­ [(methylsulfonyl)amino]naphthalene-2-yl}phenyl)-2,6-dioxo-3,6 …
Matched Description: … categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and ... [DB00503] for genotype 1b and with [DB00811] for genotype 1a of Hepatitis C [L852]. ... Dasabuvir is a non-nucleoside NS5B inhibitor which binds to the palm domain of NS5B and induces a conformational …
Matched Salts name: … Dasabuvir sodium ... Dasabuvir sodium monohydrate …
Matched Categories: … dasabuvir, ombitasvir, paritaprevir and ritonavir ... Sulfur Compounds …
Matched Products: … EXVIERA 250 MG FILM KAPLI TABLET,56 TABLET …
Albusomatropin has been used in trials studying the treatment of Growth Hormone-Deficiency and Growth Hormone Deficiency.
Investigational
Matched Synonyms: … SOMATROPIN-ALBUMIN FUSION PROTEIN ... RECOMBINANT HUMAN ALBUMIN-RECOMBINANT HUMAN GROWTH HORMONE FUSION PROTEIN
Matched Description: … Albusomatropin has been used in trials studying the treatment of Growth Hormone-Deficiency and Growth …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Proteins ... Blood Proteins ... Recombinant Proteins
Experimental
Matched Name: … (1R)-menthyl hexyl phosphonate group …
Efruxifermin is under investigation in clinical trial NCT06215716 (A Study Evaluating Efruxifermin in Subjects With Non-cirrhotic Nonalcoholic Steatohepatitis (Nash)/metabolic Dysfunction-associated Steatohepatitis (MASH) and Fibrosis).
Investigational
Matched Synonyms: … Immunoglobulin g (synthetic human constant domain fc fragment) fusion protein with fibroblast growth ... (ggggs)3 fusion protein with fibroblast growth factor 21 (98-arginine,171-glycine,180-glutamic acid) ... Immunoglobulin g1 (human .gamma.1-chain c-region c-terminal fragment) fusion protein with peptide linker …
Matched Description: … ) and Fibrosis). ... Non-cirrhotic Nonalcoholic Steatohepatitis (Nash)/metabolic Dysfunction-associated Steatohepatitis (MASH
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Proteins ... Recombinant Proteins
Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human insulin-like growth factor 2. It is being investigated for the treatment of mucopolysaccharidosis type IIIB (MPS IIIB), also known as Sanfilippo syndrome B.
Investigational
Matched Synonyms: … NAGLU-IGF2 fusion protein ... Alpha-N-acetyglucosaminidase-insulin-like-growth-factor-2 fusion protein
Matched Description: … Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Enzymes and Coenzymes ... Proteins ... Blood Proteins
Inbakicept is a dimeric human IL-15 receptor α (IL-15Rα) sushi domain/human IgG1 Fc fusion protein. It is one of the active ingredients in Anktiva, a combination product also containing nogapendekin alfa, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA...
Investigational
Matched Synonyms: … ALT-803 COMPONENT IL-15R.ALPHA.SU/FC FUSION PROTEIN ... N-803 COMPONENT IL-15R.ALPHA.SU/FC FUSION PROTEIN ... CHAIN (HUMAN SUSHI DOMAIN-CONTAINING FRAGMENT) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (HUMAN FC FRAGMENT …
Matched Description: … 75% of all bladder tumours, is commonly treated with transurethral resection of the bladder tumour and ... proliferation of natural killer cells and CD8+ memory T cells, which also synergistically enhance BCG ... Inbakicept, in combination with nogapendekin alfa, mimics the actions of IL-15, stimulating the activation and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Recombinant Proteins
Investigational
Matched Synonyms: … -4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-yl)oxy)ethoxy)carbonyl)amino)butane-1,1-diyl)bis(hydrogen phosphonate
Matched Salts name: … BR-007 sodium
Investigational
Matched Synonyms: … EXOENZYME C3 TRANSFERASE (CLOSTRIDIUM BOTULINUM VARIANT VX-210) FUSION PROTEIN WITH TRANSPORT PEPTIDE …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Proteins ... Bacterial Proteins
Investigational
Matched Synonyms: … Heat shock protein-peptide complex-96 vaccine …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins
Experimental
Matched Name: … (3,4,8b-Trimethyl-3-oxido-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-3-ium-7-yl) N-(2-ethylphenyl)carbamate
Experimental
Matched Name: … 1-3 Sugar Ring of Pentamannosyl 6-Phosphate
Experimental
Matched Name: … 2'-deoxy-5-(hydroxymethyl)uridine 5'-(dihydrogen phosphate) …
PBFT02 is a non-replicating recombinant adeno-associated virus serotype 1 vector delivering human GRN gene encoding the protein progranulin.
Investigational
Matched Synonyms: … Non-replicating recombinant adeno-associated virus serotype 1 vector delivering human GRN gene encoding the protein
Matched Description: … non-replicating recombinant adeno-associated virus serotype 1 vector delivering human GRN gene encoding the protein
Amisulpride is a benzamide derivative and a dopamine receptor antagonist that selectively works on dopamine D2 and D3 receptors. As an antipsychotic agent, amisulpride alleviates both positive and negative symptoms of schizophrenia, and it exhibits antidepressant properties in patients with psychiatric disorders, dysthymia, and major depression. Amisulpride predominantly works in...
Approved
Investigational
Matched Description: … D2 and D3 receptors. ... , and it exhibits antidepressant properties in patients with psychiatric disorders, dysthymia, and major ... Amisulpride is a benzamide derivative and a dopamine receptor antagonist that selectively works on dopamine …
Matched Categories: … Benzamides and benzamide derivatives …
Matched Products: … ., SCORED FILM-COATED TABLET ... AMISULPRIDLICH 400MG FILMT ... SOLIAN 400MG SCORED FILM-COATED TABLET …
Pecan allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Carya illinoinensis seed
Gefurulimab is under investigation in clinical trial NCT05556096 (Safety and Efficacy of ALXN1720 in Adults With Generalized Myasthenia Gravis).
Investigational
Matched Synonyms: … ANTI-(HUMAN SERUM ALBUMIN) (HUMAN-LAMA GLAMA MONOCLONAL ALXN1720 SINGLE-DOMAIN VHH FRAGMENT) FUSION PROTEIN ... WITH PEPTIDE LINKER (SYNTHETIC 15 AMINO-ACID) FUSION PROTEIN WITH ANTI-(HUMAN COMPLEMENT C5) (HUMAN-LAMA …
Matched Description: … Gefurulimab is under investigation in clinical trial NCT05556096 (Safety and Efficacy of ALXN1720 in …
Investigational
Matched Name: … Recombinant human palmitoyl protein thioesterase-1 …
Rosiglitazone is an anti-diabetic drug in the thiazolidinedione class of drugs. It is marketed by the pharmaceutical company GlaxoSmithKline as a stand-alone drug (Avandia) and in combination with metformin (Avandamet) or with glimepiride (Avandaryl). Like other thiazolidinediones, the mechanism of action of rosiglitazone is by activation of the intracellular receptor...
Approved
Investigational
Matched International brands: … Sheng Ao ... Sheng Min …
Matched Description: … It is marketed by the pharmaceutical company GlaxoSmithKline as a stand-alone drug (Avandia) and in combination ... Rosiglitazone is a selective ligand of PPARγ, and has no PPARα-binding action. ... resistance, it appears to have an anti-inflammatory effect: nuclear factor kappa-B (NFκB) levels fall and
Matched Categories: … Alimentary Tract and Metabolism ... Sulfur Compounds ... metformin and rosiglitazone ... glimepiride and rosiglitazone …
Experimental
Matched Name: … (1S)-menthyl hexyl phosphonate group …
Displaying drugs 1426 - 1450 of 1940 in total