Displaying drugs 1451 - 1475 of 2048 in total
Unasnemab
Unasnemab is under investigation in clinical trial NCT04683848 (Study to Assess the Efficacy and Safety of MT-3921 in Subjects With Acute Traumatic Cervical Spinal Cord Injury).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human repulsive guidance molecule rgma) (human-mus musculus clone rh116a3 .gamma ... .1-chain), disulfide with human-mus musculus clone rh116a3 .kappa. …
Matched Description: … Unasnemab is under investigation in clinical trial NCT04683848 (Study to Assess the Efficacy and Safety …
Matched Description: … Unasnemab is under investigation in clinical trial NCT04683848 (Study to Assess the Efficacy and Safety …
Galegenimab
Galegenimab is under investigation in clinical trial NCT03972709 (A Study Assessing the Safety, Tolerability, and Efficacy of Galegenimab (FHTR2163) in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration (AMD)).
Investigational
Matched Synonyms: … Immunoglobulin igg1 fab fragment, anti-(human serine proteinase htra1) (human-mus musculus monoclonal ... fhtr2163 .gamma.1-chain), disulfide with human-mus musculus monoclonal fhtr2163 .kappa. …
Matched Description: … Galegenimab is under investigation in clinical trial NCT03972709 (A Study Assessing the Safety, Tolerability, and …
Matched Description: … Galegenimab is under investigation in clinical trial NCT03972709 (A Study Assessing the Safety, Tolerability, and …
Posdinemab
Posdinemab is under investigation in clinical trial NCT04619420 (A Study of JNJ-63733657 in Participants With Early Alzheimer's Disease).
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human phosphorylated tau protein) (human-Mus musculus monoclonal JNJ-63733657 ... γ1-chain), disulfide with human-Mus musculus monoclonal JNJ-63733657 κ-chain, dimer …
Human adenovirus b serotype 7
Human adenovirus b serotype 7 is a vaccine.
Approved
Matched Synonyms: … Human Adenovirus B Serotype 7 Strain 55142 …
Matched Name: … Human adenovirus b serotype 7 …
Matched Description: … Human adenovirus b serotype 7 is a vaccine. …
Matched Name: … Human adenovirus b serotype 7 …
Matched Description: … Human adenovirus b serotype 7 is a vaccine. …
Pegylated Recombinant Human Arginase I
Pegylated Recombinant Human Arginase I is under investigation in clinical trial NCT03455140 (A Study Evaluating the Safety and Activity of Pegylated Recombinant Human Arginase (BCT-100)).
Investigational
Matched Synonyms: … Pegylated recombinant human arginase i bct-100 …
Matched Name: … Pegylated Recombinant Human Arginase I …
Matched Description: … Evaluating the Safety and Activity of Pegylated Recombinant Human Arginase (BCT-100)). ... Pegylated Recombinant Human Arginase I is under investigation in clinical trial NCT03455140 (A Study …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Name: … Pegylated Recombinant Human Arginase I …
Matched Description: … Evaluating the Safety and Activity of Pegylated Recombinant Human Arginase (BCT-100)). ... Pegylated Recombinant Human Arginase I is under investigation in clinical trial NCT03455140 (A Study …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Staphylococcus aureus immune globulin (human)
Investigational
Matched Name: … Staphylococcus aureus immune globulin (human) …
Recombinant human CD4 immunoglobulin G
Investigational
Matched Synonyms: … Recombinant human CD4 immunoglobulin G …
Matched Name: … Recombinant human CD4 immunoglobulin G …
Matched Name: … Recombinant human CD4 immunoglobulin G …
Allogeneic Cardiosphere-Derived Cells
Cardiosphere-derived cells (CDCs) are derived from human neonatal heart tissue with a distinct antigenic profile (CD105+, CD45-, and CD90low). They exert their effects by secreting exosomes: nanometer-sized, membrane-bound vesicles used for the purpose of cell-cell communication. CDCs target multiple cytokine pathways associated with poor outcomes (e.g. TNFa, IFN-y, IL-1B, and...
Investigational
Matched Name: … Allogeneic Cardiosphere-Derived Cells …
Matched Description: … Cardiosphere-derived cells (CDCs) are derived from human neonatal heart tissue with a distinct antigenic ... profile (CD105+, CD45-, and CD90low). ... TNFa, IFN-y, IL-1B, and IL-15). …
Matched Description: … Cardiosphere-derived cells (CDCs) are derived from human neonatal heart tissue with a distinct antigenic ... profile (CD105+, CD45-, and CD90low). ... TNFa, IFN-y, IL-1B, and IL-15). …
CHO Cells Recombinant Vaccine
This vaccine candidate, developed in China, uses SARS-CoV-2 protein subunits that are entirely engineered, created, and secreted by Chinese Hamster Ovary (CHO) cells . The vaccine candidate is sponsored by Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd. and is undergoing phase I clinical trials to evaluate safety and tolerability.
Investigational
Matched Name: … CHO Cells Recombinant Vaccine …
Matched Description: … candidate, developed in China, uses SARS-CoV-2 protein subunits that are entirely engineered, created, and ... phase I clinical trials to evaluate safety and tolerability. ... The vaccine candidate is sponsored by Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd. and is undergoing …
Matched Description: … candidate, developed in China, uses SARS-CoV-2 protein subunits that are entirely engineered, created, and ... phase I clinical trials to evaluate safety and tolerability. ... The vaccine candidate is sponsored by Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd. and is undergoing …
Echinacea angustifolia root
Approved
Experimental
Matched Synonyms: … Narrow-leaf echinacea root ... Narrow-leaf purple coneflower root …
Apitegromab
Apitegromab is under investigation in clinical trial NCT03921528 (An Active Treatment Study of SRK-015 in Patients With Type 2 or Type 3 Spinal Muscular Atrophy).
Investigational
Matched Synonyms: … Immunoglobulin g4 (234-proline), anti-(human progrowth differentiation factor 8) (human monoclonal srk ... -015 .gamma.4-chain), disulfide with human monoclonal srk-015 .lambda. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Briquilimab
Briquilimab is a humanized aglycosylated IgG1 kappa monoclonal antibody targeting CD117 (cKit).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1 (297-GLUTAMINE), ANTI-(HUMAN C-KIT RECEPTOR) (HUMAN-MUS MUSCULUS MONOCLONAL JSP191 ... .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL JSP191 .KAPPA. …
Tagitanlimab
Investigational
Matched Synonyms: … Immunoglobulin g1 (237-alanine,238-alanine,240-alanine), anti-(human programmed death-ligand 1) (human ... monoclonal kla167 .gamma.1-chain), disulfide with human monoclonal kla167 .kappa. …
Amlitelimab
Amlitelimab is under investigation in clinical trial NCT06181435 (A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (COAST 2)).
Investigational
Matched Synonyms: … Immunoglobulin g4 (235-proline,242-glutamic acid), anti-(human ox40 ligand) (human monoclonal ky1005- ... 2d10 .gamma.4-chain), disulfide with human monoclonal ky1005-2d10 .kappa. …
Matched Description: … Amlitelimab is under investigation in clinical trial NCT06181435 (A Study to Evaluate the Efficacy and ... Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and …
Matched Description: … Amlitelimab is under investigation in clinical trial NCT06181435 (A Study to Evaluate the Efficacy and ... Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and …
Olinvacimab
Olinvacimab is under investigation in clinical trial NCT03033524 (Trial to Evaluate the Safety of Ttac-0001(tanibirumab) in Recurrent Glioblastoma).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human vascular endothelial growth factor receptor 2) (human monoclonal ttac- ... Fully human monoclonal antibody targets vascular endothelial growth factor receptor 2 ... 0001 heavy chain), disulfide with human monoclonal ttac-0001 light chain, dimer …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Carisoprodol
Originally approved by the FDA in 1959 [FDA label], carisoprodol is a centrally acting muscle relaxant used in painful musculoskeletal conditions in conjunction with physical therapy and other medications . This drug is available by itself in an oral tablet or combined with aspirin, or in a fixed-dose combination with...
Approved
Matched Synonyms: … (±)-2-methyl-2-propyl-1,3-propanediol carbamate isopropylcarbamate ... 2-methyl-2-propyltrimethylene carbamate isopropylcarbamate ... 2-methyl-2-propyl-1,3-propanediol carbamate isopropylcarbamate …
Matched Iupac: … 2-[(carbamoyloxy)methyl]-2-methylpentyl N-(propan-2-yl)carbamate …
Matched Description: … acting muscle relaxant used in painful musculoskeletal conditions in conjunction with physical therapy and ... itself in an oral tablet or combined with aspirin, or in a fixed-dose combination with both aspirin and …
Matched Mixtures name: … Carisoprodol and Aspirin ... Carisoprodol and Aspirin ... Carisoprodol and Aspirin …
Matched Iupac: … 2-[(carbamoyloxy)methyl]-2-methylpentyl N-(propan-2-yl)carbamate …
Matched Description: … acting muscle relaxant used in painful musculoskeletal conditions in conjunction with physical therapy and ... itself in an oral tablet or combined with aspirin, or in a fixed-dose combination with both aspirin and …
Matched Mixtures name: … Carisoprodol and Aspirin ... Carisoprodol and Aspirin ... Carisoprodol and Aspirin …
Ciltacabtagene autoleucel
Multiple myeloma is a malignancy involving the plasma cells of the bone marrow. It is a rare malignancy, with an estimated yearly incidence of 6.5 people per 100,000, and is variable in its presentation - some patients may remain entirely asymptomatic, while others may experience a range of symptoms including...
Approved
Investigational
Matched Synonyms: … Autologous bi-epitope BCMA-targeted CAR T-cells …
Matched Description: … plasma cells and most multiple myeloma cell lines, making it a choice target in the development of immunotherapies ... [A245854] While normally expressed on plasma blasts and plasma cells, BCMA is widely expressed on malignant ... It is a rare malignancy, with an estimated yearly incidence of 6.5 people per 100,000,[L40749] and is …
Matched Categories: … Antineoplastic cell and gene therapy ... Antineoplastic and Immunomodulating Agents …
Matched Description: … plasma cells and most multiple myeloma cell lines, making it a choice target in the development of immunotherapies ... [A245854] While normally expressed on plasma blasts and plasma cells, BCMA is widely expressed on malignant ... It is a rare malignancy, with an estimated yearly incidence of 6.5 people per 100,000,[L40749] and is …
Matched Categories: … Antineoplastic cell and gene therapy ... Antineoplastic and Immunomodulating Agents …
Tisagenlecleucel
Tisagenlecleucel is a CD19-directed genetically modified autologous T cell immunotherapy, or a CAR-T cell therapy for B-cell acute lymphoblastic leukemia. It was granted approval by FDA in August 2017 under the market name Kymriah. Tisagenlecleucel is an immunocellular therapy that involves autologous T cells that are collected from each individual...
Approved
Investigational
Matched Synonyms: … CAR.CD19-Redirected T cells …
Matched Description: … These CD19-directed chimeric antigen receptors (CD19 CAR-T cells) direct the T cells to target and kill ... each individual patient and genetically engineered to express a specific protein called a chimeric antigen ... In a multicenter clinical trial involving pediatric and young adult patients with relapsed or refractory …
Matched Categories: … Antineoplastic cell and gene therapy ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Genetically-modified Autologous T Cells …
Matched Description: … These CD19-directed chimeric antigen receptors (CD19 CAR-T cells) direct the T cells to target and kill ... each individual patient and genetically engineered to express a specific protein called a chimeric antigen ... In a multicenter clinical trial involving pediatric and young adult patients with relapsed or refractory …
Matched Categories: … Antineoplastic cell and gene therapy ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Genetically-modified Autologous T Cells …
Recombinant SARS-CoV-2 Vaccine (Sf9 Cell)
The Recombinant SARS-CoV-2 Vaccine was created by inserting genes of the SARS-CoV-2 spike protein’s receptor-binding domain into a baculovirus expression system[F4738, A226853]. In pre-clinical trial testing on mice, rabbits, and non-human primates, the candidate was able to induce a functional antibody response within 7-14 days of initial injection . It...
Investigational
Matched Name: … Recombinant SARS-CoV-2 Vaccine (Sf9 Cell) …
Matched Description: … In pre-clinical trial testing on mice, rabbits, and non-human primates, the candidate was able to induce ... These promising results have secured a Phase I trial (NCT04530656) to evaluate the safety, efficacy, and ... It also provided protection in non-human primates to an in vivo challenge with SARS-CoV-2[A226853]. …
Matched Description: … In pre-clinical trial testing on mice, rabbits, and non-human primates, the candidate was able to induce ... These promising results have secured a Phase I trial (NCT04530656) to evaluate the safety, efficacy, and ... It also provided protection in non-human primates to an in vivo challenge with SARS-CoV-2[A226853]. …
Asunercept
Asunercept is under investigation in clinical trial NCT02853565 (A Study of CAN008 for Newly Diagnosed Glioblastoma Multiforme).
Investigational
Matched Synonyms: … FAS ANTIGEN (HUMAN EXTRACELLULAR DOMAIN FRAGMENT) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (HUMAN FC FRAGMENT …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ontorpacept
Investigational
Matched Synonyms: … (human) fusion protein with immunoglobulin g1 (human fc fragment), dimer …
Efineptakin alfa
Efineptakin alfa (also known as NT-I7) is a long-acting human interleukin-7 (IL-7) fusion protein that promotes T-cell development, contributing to the immune response. Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better bioavailability. This drug is currently being investigated in the areas...
Investigational
Matched Synonyms: … Recombinant human IL-7-HYFC ... Recombinant human interleukin-7 fused to a hybrid crystallizable fragment region of a human antibody ... Recombinant human interleukin-7 fused to a hybrid crystallizable fragment region of a human antibody …
Matched Description: … Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better ... This drug is currently being investigated in the areas of oncology, immunology, and infectious disease ... promotes T-cell development, contributing to the immune response. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better ... This drug is currently being investigated in the areas of oncology, immunology, and infectious disease ... promotes T-cell development, contributing to the immune response. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Didanosine
A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral...
Approved
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors ... Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor …
Matched Products: … DE LIBERACION RETARDADA X 125 MG ... DE LIBERACION RETARDADA X 400 MG …
Matched Products: … DE LIBERACION RETARDADA X 125 MG ... DE LIBERACION RETARDADA X 400 MG …
ATI-1013
ATI-1013 is a fully human nicotine-specific monoclonal antibody.
Investigational
Matched Synonyms: … Fully human nicotine-specific monoclonal antibody …
Matched Description: … ATI-1013 is a fully human nicotine-specific monoclonal antibody. …
Matched Description: … ATI-1013 is a fully human nicotine-specific monoclonal antibody. …
Displaying drugs 1451 - 1475 of 2048 in total