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Displaying drugs 14976 - 15000 of 15549 in total

Trofosfamide

Trofosfamide has been used in trials studying the treatment of Ependymomas, Medulloblastomas, Sarcoma, Soft Tissue, Supratentorial PNETs, and Recurrent Brain Tumors.
Investigational
Matched Iupac: … 2-[bis(2-chloroethyl)amino]-3-(2-chloroethyl)-1,3,2lambda5-oxazaphosphinan-2-one …
Matched Description: … Trofosfamide has been used in trials studying the treatment of Ependymomas, Medulloblastomas, Sarcoma …

Sus scrofa placenta

Sus scrofa placenta is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Sus scrofa placenta is an animal extract used in some OTC (over-the-counter) products. …

OPB-111077

OPB-111077 is a novel inhibitor of STAT3 and mitochondrial oxidative phosphorylation. It has demonstrated promising anticancer activity in preclinical models.
Investigational
Matched Description: … It has demonstrated promising anticancer activity in preclinical models. ... OPB-111077 is a novel inhibitor of STAT3 and mitochondrial oxidative phosphorylation. …

Satavaptan

Satavaptan is under investigation in clinical trial NCT00359437 (Satavaptan in the Prevention of Ascites Recurrence in Patients With Ascites Due to Cirrhosis of the Liver).
Investigational
Matched Iupac: … N-tert-butyl-3-methoxy-4-{[(1s,4s)-5'-ethoxy-4-[2-(morpholin-4-yl)ethoxy]-2'-oxo-1',2'-dihydrospiro[cyclohexane …
Matched Description: … Satavaptan is under investigation in clinical trial NCT00359437 (Satavaptan in the Prevention of Ascites ... Recurrence in Patients With Ascites Due to Cirrhosis of the Liver). …

Recombinant Human Thrombopoietin

Recombinant human thrombopoietin is a full-length glycosylated cytokine produced by Chinese hamster ovary cells and is used to promote the generation of megakaryocytes and platelets.[A225691, A225696] This drug is used in the treatment of thrombocytopenia.
Investigational
Matched Description: … [A225691, A225696] This drug is used in the treatment of thrombocytopenia. ... Recombinant human thrombopoietin is a full-length glycosylated cytokine produced by Chinese hamster ovary …

Vorsetuzumab mafodotin

Vorsetuzumab mafodotin is under investigation in clinical trial NCT01677390 (A Phase 1b Study of SGN-75 in Combination With Everolimus in Patients With Renal Cell Carcinoma).
Investigational
Matched Description: … Vorsetuzumab mafodotin is under investigation in clinical trial NCT01677390 (A Phase 1b Study of SGN- ... 75 in Combination With Everolimus in Patients With Renal Cell Carcinoma). …

Letaplimab

Letaplimab is under investigation in clinical trial NCT04485052 (Efficacy and Safety Evaluation of IBI188 in Combination With Azacitidine in Treatment of Patients With Acute Myeloid Leukemia).
Investigational
Matched Description: … in Combination With Azacitidine in Treatment of Patients With Acute Myeloid Leukemia). ... Letaplimab is under investigation in clinical trial NCT04485052 (Efficacy and Safety Evaluation of IBI188 …

Betacetylmethadol

A narcotic analgesic with a long onset and duration of action. It is used mainly in the treatment of narcotic dependence. [PubChem]
Experimental
Illicit
Matched Iupac: … (3S,6R)-6-(dimethylamino)-4,4-diphenylheptan-3-yl acetate …
Matched Description: … It is used mainly in the treatment of narcotic dependence. [PubChem] ... A narcotic analgesic with a long onset and duration of action. …

REP8839

REP8839 is a novel methionyl-tRNA synthetase (MetS) inhibitor being developed by Replidyne (GlaxoSmithKline licensed REP8839 to Replidyne in June of 2003).
Investigational
Matched Description: … licensed REP8839 to Replidyne in June of 2003). ... REP8839 is a novel methionyl-tRNA synthetase (MetS) inhibitor being developed by Replidyne (GlaxoSmithKline …

Dactolisib

Dactolisib has been used in trials studying the treatment of Cancer, Solid Tumor, Renal Cancer, Breast Cancer, and Cowden Syndrome, among others.
Investigational
Matched Iupac: … 2-methyl-2-{4-[3-methyl-2-oxo-8-(quinolin-3-yl)-1H,2H,3H-imidazo[4,5-c]quinolin-1-yl]phenyl}propanenitrile …
Matched Description: … Dactolisib has been used in trials studying the treatment of Cancer, Solid Tumor, Renal Cancer, Breast …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Uprosertib

Uprosertib has been used in trials studying the treatment of Cancer, Melanoma, Solid Tumours, Cervical Cancer, and HER2/Neu Negative, among others.
Investigational
Matched Iupac: … N-[(2S)-1-amino-3-(3,4-difluorophenyl)propan-2-yl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)furan ... -2-carboxamide …
Matched Description: … Uprosertib has been used in trials studying the treatment of Cancer, Melanoma, Solid Tumours, Cervical …
Matched Salts cas: … 1047635-80-2 …

Merestinib

Merestinib has been used in trials studying the treatment of Cancer, Solid Tumor, Advanced cancer, ColoRectal Cancer, and Metastatic Cancer, among others.
Investigational
Matched Iupac: … 2-oxo-1,2-dihydropyridine-3-carboxamide ... N-(3-fluoro-4-{[1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl]oxy}phenyl)-1-(4-fluorophenyl)-6-methyl- …
Matched Description: … Merestinib has been used in trials studying the treatment of Cancer, Solid Tumor, Advanced cancer, ColoRectal …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Ombrabulin

Ombrabulin has been used in trials studying the treatment of Sarcoma, Neoplasms, Solid Tumor, Neoplasms, Malignant, and Advanced Solid Tumors, among others.
Investigational
Matched Iupac: … (2S)-2-amino-3-hydroxy-N-{2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl}propanamide …
Matched Description: … Ombrabulin has been used in trials studying the treatment of Sarcoma, Neoplasms, Solid Tumor, Neoplasms …
Matched Salts cas: … 253426-24-3 …

Samarium Sm-153

Samarium 153 has been used in trials studying the supportive care of Pain, Lung Cancer, Breast Cancer, Prostate Cancer, and Metastatic Cancer.
Investigational
Matched Description: … Samarium 153 has been used in trials studying the supportive care of Pain, Lung Cancer, Breast Cancer …

Typhonium giganteum whole

Typhonium giganteum whole is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Typhonium giganteum whole is a plant/plant extract used in some OTC (over-the-counter) products. …

Sevuparin

Sevuparin is under investigation in clinical trial NCT03853421 (Placebo-controlled Study to Determine the Safety and Tolerability of Subcutaneous Doses of Sevuparin).
Investigational
Matched Description: … Sevuparin is under investigation in clinical trial NCT03853421 (Placebo-controlled Study to Determine …

MBL-HCV1

MBL-HCV1 is a monoclonal antibody developed to prevent the recurrence of hepatitis C virus (HCV) in patients receiving a liver transplant.
Investigational
Matched Description: … MBL-HCV1 is a monoclonal antibody developed to prevent the recurrence of hepatitis C virus (HCV) in patients ... receiving a liver transplant. …

GDC-0425

GDC-0425 is under investigation in clinical trial NCT01359696 (A Study Evaluating the Safety, Tolerability, and Pharmacokinetics of GDC-0425 Administered With and Without Gemcitabine in Patients With Refractory Solid Tumors or Lymphoma).
Investigational
Matched Iupac: … 3-[(1-ethylpiperidin-4-yl)oxy]-5,8,10-triazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaene …
Matched Description: … GDC-0425 is under investigation in clinical trial NCT01359696 (A Study Evaluating the Safety, Tolerability ... , and Pharmacokinetics of GDC-0425 Administered With and Without Gemcitabine in Patients With Refractory …

Nesvacumab

Nesvacumab is under investigation in clinical trial NCT01997164 (Study of Intravitreal (IVT) REGN910-3 and IVT REGN910 in Patients With Either Neovascular (Wet) Age Related Macular Degeneration (AMD) or Diabetic Macular Edema (DME)).
Investigational
Matched Description: … 3 and IVT REGN910 in Patients With Either Neovascular (Wet) Age Related Macular Degeneration (AMD) or ... Nesvacumab is under investigation in clinical trial NCT01997164 (Study of Intravitreal (IVT) REGN910- …

Licogliflozin

Licogliflozin is under investigation in clinical trial NCT03320941 (A Dose-finding Study to Evaluate the Change in Weight After Treatment With LIK066 in Japanese Patients With Obesity).
Investigational
Matched Iupac: … (2S,3R,4R,5S,6R)-2-{3-[(2,3-dihydro-1,4-benzodioxin-6-yl)methyl]-4-ethylphenyl}-6-(hydroxymethyl)oxane …
Matched Description: … Licogliflozin is under investigation in clinical trial NCT03320941 (A Dose-finding Study to Evaluate ... the Change in Weight After Treatment With LIK066 in Japanese Patients With Obesity). …
Matched Categories: … Sodium-Glucose Transporter 2 Inhibitors …

Oxelumab

Oxelumab is under investigation in clinical trial NCT00983658 (A Study of HuMAb OX40L in the Prevention of Allergen-induced Airway Obstruction in Adults With Mild Allergic Asthma).
Investigational
Matched Description: … Oxelumab is under investigation in clinical trial NCT00983658 (A Study of HuMAb OX40L in the Prevention ... of Allergen-induced Airway Obstruction in Adults With Mild Allergic Asthma). …

Serabelisib

Serabelisib is under investigation in clinical trial NCT02625259 (A Study to Evaluate the Relative Bioavailability, Effect of Food, and Gastric Potential Hydrogen (pH) Modification on the Pharmacokinetics of TAK-117 (MLN1117) in Healthy Participants).
Investigational
Matched Iupac: … 5-[3-(morpholine-4-carbonyl)imidazo[1,2-a]pyridin-6-yl]-1,3-benzoxazol-2-amine …
Matched Description: … Serabelisib is under investigation in clinical trial NCT02625259 (A Study to Evaluate the Relative Bioavailability ... Food, and Gastric Potential Hydrogen (pH) Modification on the Pharmacokinetics of TAK-117 (MLN1117) in …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Dexmecamylamine

Dexmecamylamine has been used in trials studying the basic science and treatment of Patients, Depression, Drug Abuse, Pharmacokinetics, and Renal Impairment, among others.
Investigational
Matched Iupac: … (1R,2S,4S)-N,2,3,3-tetramethylbicyclo[2.2.1]heptan-2-amine …
Matched Description: … Dexmecamylamine has been used in trials studying the basic science and treatment of Patients, Depression …

PF-00610355

PF-00610355 has been used in trials studying the treatment of Lung Disease, Moxifloxacin, Pulmonary Disease, Asthma, Bronchial, and Bronchial Diseases, among others.
Investigational
Matched Iupac: … 2-[3-(2-{[(2R)-2-hydroxy-2-(4-hydroxy-3-methanesulfonamidophenyl)ethyl]amino}-2-methylpropyl)phenyl]- ... N-({4'-hydroxy-[1,1'-biphenyl]-3-yl}methyl)acetamide …
Matched Description: … PF-00610355 has been used in trials studying the treatment of Lung Disease, Moxifloxacin, Pulmonary Disease …
Matched Categories: … Adrenergic beta-2 Receptor Agonists …

Lanicemine

Lanicemine has been used in trials studying the treatment and basic science of Depression, Major Depressive Disorder, and Treatment Resistant Major Depressive Disorder.
Investigational
Matched Iupac: … (1S)-1-phenyl-2-(pyridin-2-yl)ethan-1-amine …
Matched Description: … Lanicemine has been used in trials studying the treatment and basic science of Depression, Major Depressive …
Displaying drugs 14976 - 15000 of 15549 in total