Displaying drugs 15101 - 15125 of 15558 in total
ETHYL 3-[4-(AMINOSULFONYL)PHENYL]PROPANOATE
Experimental
Thienylfentanyl
Thienylfentanyl is a fentanyl analog analgesic that was sold on the black market in the 1980s until the Federal Analog Act scheduled drugs based on structural similarity rather than scheduling drugs individually. Thienylfentanyl has a similar synthesis pathway to fentanyl except 2-(2-bromoethyl)thiophene is substituted for phenethyl bromide.
Illicit
ANX-510
ANX-510 (CoFactor) is a folate-based biomodulator drug being developed to enhance the activity and reduce associated toxicity of the widely used cancer chemotherapy, 5-fluorouracil (5-FU). CoFactor use with 5-FU is being evaluated in clinical trials in first line treatment of metastatic colorectal cancer.
Investigational
Matched Description: … ANX-510 (CoFactor) is a folate-based biomodulator drug being developed to enhance the activity and reduce …
Cathinone
Cathinone is a monoamine alkaloid found in the shrub Catha edulis (Khat). Closely related to ephedrine, cathine and other amphetamines, it is probably the main contributor to the stimulant effect of Catha edulis. Cathinone differs from many other amphetamines in that its structure is a ketone. Other amphetamines to share...
Illicit
Matched Description: … Closely related to ephedrine, cathine and other amphetamines, it is probably the main contributor to ... Other amphetamines to share this structure include the antidepressant bupropion and the stimulant methcathinone …
Irofulven
A novel anti-cancer compound synthesized by scientists at the University of California, San Diego more than a decade ago from toxins of the poisonous jack-o-lantern mushroom, has been granted “fast track” status by the U.S. Food and Drug Administration (FDA) after demonstrating promise against one of the most deadly cancers....
Investigational
Matched Description: … Food and Drug Administration (FDA) after demonstrating promise against one of the most deadly cancers ... Phase III clinical trials involving the drug have been underway since early 2001 at sites in the U.S. and …
Robenidine
Robenidine is identified as a coccidiostat drug, which slows both the growth and reproductive cycles of coccidian parasites. Robenidine is used to control coccidiosis, a lethal infection in poultry which has shown a significant economic burden. Despite the availability of other agents to treat coccidiosis, robenidine has been proven to...
Experimental
Vet approved
Matched Description: … Robenidine is identified as a coccidiostat drug, which slows both the growth and reproductive cycles ... been proven to be effective in delaying the development of antibiotic resistance through intermittent and …
Poloxalene
Ethylene oxide/propylene oxide copolymer is used as a food additive. It belongs to the family of Epoxides. These are compounds containing a cyclic ether with three ring atoms (one oxygen and two carbon atoms).
Investigational
Vet approved
Matched Description: … These are compounds containing a cyclic ether with three ring atoms (one oxygen and two carbon atoms) …
1h-Benoximidazole-2-Carboxylic Acid
Experimental
4,5,6,7-Tetrachloro-3h-Isobenzofuran-1-One
Experimental
SB220025
Experimental
1-Naphthyl-L-alanine
Experimental
Ethadione
Experimental
ABH001
ABH001 is under investigation in clinical trial NCT01749306 (A Study of the Efficacy and Safety of ABH001 in the Treatment of Patients With Epidermolysis Bullosa Who Have Wounds That Are Not Healing).
Investigational
Matched Description: … ABH001 is under investigation in clinical trial NCT01749306 (A Study of the Efficacy and Safety of ABH001 …
NM-702
Nissan Chemical and Taisho have been jointly developing NM-702, a drug for the treatment of arteriosclerosis obliterans.
M-702 is an orally active inhibitor of phosphodiesterase and thromboxane synthetase. In Japan, Phase 2 studies are being conducted for intermittent claudication caused by arteriosclerosis obliterans, intermittent claudication caused by spinal canal stenosis,...
Investigational
Matched Description: … M-702 is an orally active inhibitor of phosphodiesterase and thromboxane synthetase. ... Nissan Chemical and Taisho have been jointly developing NM-702, a drug for the treatment of arteriosclerosis ... claudication caused by arteriosclerosis obliterans, intermittent claudication caused by spinal canal stenosis, and …
(2R)-2-PHENYL-N-PYRIDIN-4-YLBUTANAMIDE
Experimental
N-acetylsulfanilyl chloride
ASC has been investigated for the screening of Patients Undergoing Screening or Surveillance Colonoscopy.
Investigational
ISIS 14803
ISIS 14803 is a 20-unit antisense phosphorothioate oligodeoxynucleotide that binds to hepatitis C virus (HCV) RNA at the translation initiation region of the internal ribosome entry site (IRES) and inhibits protein expression in cell culture.
Investigational
Matched Description: … hepatitis C virus (HCV) RNA at the translation initiation region of the internal ribosome entry site (IRES) and …
Ala-geninthiocin
Ala-geninthiocin is a novel thiopeptide antibacterial compound derived from marine Streptomyces species. It has exhibited potent in vitro activity against gram-positive bacteria including Staphylococcus aureus, Bacillus subtilis, Mycobacterium smegmatis, and Micrococcus luteus.
Experimental
Matched Iupac: … carbamoylethyl]-2-{[(14S,17Z,27S)-17-ethylidene-14-[(1S)-1-hydroxyethyl]-27-(2-hydroxypropan-2-yl)-33-methyl …
Matched Description: … gram-positive bacteria including _Staphylococcus aureus_, _Bacillus subtilis_, _Mycobacterium smegmatis_, and …
Matched Description: … gram-positive bacteria including _Staphylococcus aureus_, _Bacillus subtilis_, _Mycobacterium smegmatis_, and …
FT-1101
FT-1101 is a novel Bromodomain and Extra-Terminal motif (BET) inhibitor. FT-1101 is under investigation in clinical trial NCT02543879 (Study of a Novel BET Inhibitor FT-1101 in Patients With Relapsed or Refractory Hematologic Malignancies).
Investigational
Matched Description: … FT-1101 is a novel Bromodomain and Extra-Terminal motif (BET) inhibitor. …
SC-236
SC-236 is a potent, selective, orally active inhibitor of cyclooxygenase-2 (COX-2) that has been studied in cancer therapy , lower back pain , and inflammation , , , .
Experimental
Investigational
Matched Description: … cyclooxygenase-2 (COX-2) [L2964] that has been studied in cancer therapy [A33375], lower back pain [A33376], and …
TOP-1288
TOP-1288 is under investigation in clinical trial NCT02888379 (Phase 2a Study to Evaluate the Safety/Tolerability and Efficacy of TOP1288 200 mg Rectal Solution Once Daily for 4 Weeks in Ulcerative Colitis).
Investigational
Matched Description: … under investigation in clinical trial NCT02888379 (Phase 2a Study to Evaluate the Safety/Tolerability and …
Displaying drugs 15101 - 15125 of 15558 in total