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Displaying drugs 1551 - 1575 of 1992 in total

BCX10013

BCX10013 is a small molecule inhibitor of human complement factor D.
Investigational
Matched Description: … BCX10013 is a small molecule inhibitor of human complement factor D. …

LYT-200

LYT-200 is a fully human IgG4 monoclonal antibody directed against galectin-9.
Investigational
Matched Description: … LYT-200 is a fully human IgG4 monoclonal antibody directed against galectin-9. …

HMI-204

HMI-204 is an adeno-associated virus serotype HSC15 expressing human arylsulfatase A
Investigational
Matched Description: … HMI-204 is an adeno-associated virus serotype HSC15 expressing human arylsulfatase A …

AVB-101

AVB-101 is a recombinant AAV9 vector encoding the human progranulin (PGRN) gene.
Investigational
Matched Description: … AVB-101 is a recombinant AAV9 vector encoding the human progranulin (PGRN) gene. …

ASP-7317

ASP-7317 consists of human embryonic stem cell-derived retinal pigment epithelium cells.
Investigational
Matched Description: … ASP-7317 consists of human embryonic stem cell-derived retinal pigment epithelium cells. …

MANF

MANF is a human recombinant mesencephalic, astrocyte-derived neurotrophic factor.
Investigational
Matched Description: … MANF is a human recombinant mesencephalic, astrocyte-derived neurotrophic factor. …

TPCA-1

TPCA-1 is a selective inhibitor of human IκB kinase 2 (IKK-2).
Investigational
Matched Description: … TPCA-1 is a selective inhibitor of human IκB kinase 2 (IKK-2).[A253152] …

Eritoran

Eritoran is a structural analogue of the lipid A portion of lipopolysaccharide (LPS). It is being developed by Eisai Research Institute of Boston for the treatment of severe sepsis.
Investigational

AVI-014

AVI-014 is a glycosylated, recombinant human granulocyte colony-stimulating factor (G-CSF).
Investigational
Matched Description: … AVI-014 is a glycosylated, recombinant human granulocyte colony-stimulating factor (G-CSF). …

BI-1206

BI-1206 is a fully human immunoglobulin G1 monoclonal antibody that targets CD32b.
Investigational
Matched Description: … BI-1206 is a fully human immunoglobulin G1 monoclonal antibody that targets CD32b. …

Cixutumumab

Cixutumumab has been used in trials studying the treatment of Lung Cancer, Malignant Neoplasm, Leukemia, Mast-Cell, Non-Small-Cell Lung Carcinoma, and Adenocarcinoma of the Prostate. Cixutumumab is a highly specific recombinant human monoclonal antibody with high affinity for the insulin-like growth factor-I receptor (IGF-IR). IGF-IR is overexpressed in a variety of...
Investigational
Matched Description: … the treatment of Lung Cancer, Malignant Neoplasm, Leukemia, Mast-Cell, Non-Small-Cell Lung Carcinoma, and ... Cixutumumab is a highly specific recombinant human monoclonal antibody with high affinity for the insulin-like …
Matched Categories: … Amino Acids, Peptides, and Proteins …

jCell

jCell is an human retinal progenitor cell therapy for retinitis pigmentosa.
Investigational
Matched Description: … jCell is an human retinal progenitor cell therapy for retinitis pigmentosa. …

Trenonacog alfa

Human coagulation factor IX (EC 3.4.21.22, Christmas factor, plasma thromboplastin component), produced in CHO cells.
Investigational
Matched Description: … Human coagulation factor IX (EC 3.4.21.22, Christmas factor, plasma thromboplastin component), produced …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …

EXOB-001

EXOB-001 consists of extracellular vesicles derived from cultured human umbilical cord mesenchymal stromal cells.
Investigational
Matched Description: … EXOB-001 consists of extracellular vesicles derived from cultured human umbilical cord mesenchymal stromal …

GSK-923295

GSK-923295 is a small-molecule inhibitor of the mitotic kinesin centromere-associated protein E (CENP-E), and the third novel drug candidate to arise from Cytokinetics' broad strategic alliance with GlaxoSmithKline (GSK). GSK-923295 demonstrated a broad spectrum of activity against a range of human tumor xenografts grown in nude mice, including models of...
Investigational
Matched Description: … and is currently in Phase I human clinical trials being conducted by GSK. ... in nude mice, including models of colon, breast, ovarian, lung and other tumors. ... 923295 is a small-molecule inhibitor of the mitotic kinesin centromere-associated protein E (CENP-E), and …

Tosedostat

Tosedostat has been used in trials studying the treatment and supportive care of AML, Leukemia, Pancreas Cancer, Multiple Myeloma, and Pancreatic Cancer, among others. Tosedostat is an inhibitor of the M1 family of aminopeptidases, in particular PuSA, and LTA4 hydrolase. It has demonstrated anti-tumour activity in a number of models...
Investigational
Matched Description: … Cancer, Multiple Myeloma, and Pancreatic Cancer, among others. ... in synergy with cytotoxic agents such as carboplatin and paclitaxel. ... Tosedostat has been used in trials studying the treatment and supportive care of AML, Leukemia, Pancreas …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Mitazalimab

Mitazalimab is under investigation in clinical trial NCT02379741 (ADC-1013 First-in-Human Study).
Investigational
Matched Description: … Mitazalimab is under investigation in clinical trial NCT02379741 (ADC-1013 First-in-Human Study). …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Echinacoside

Echinacoside is a phenylethanoid glycoside isolated from Echinacea angustifolia in 1950, and currently being investigated for the treatment of Parkinson's, Alzheimer's, atherosclerosis, osteoporosis, acute colitis, wound treatment, and hepatitis. Echinacoside has demonstrated inhibition of apoptosis in neural cell lines, demonstrating potential for use in the treatment of neurological conditions.
Experimental
Matched Description: … Echinacoside is a phenylethanoid glycoside isolated from _Echinacea angustifolia_ in 1950, and currently ... treatment of Parkinson's, Alzheimer's, atherosclerosis, osteoporosis, acute colitis, wound treatment, and …
Matched Categories: … Herbs and Natural Products …

JNJ-27390467

JNJ-27390467 is a potent, nonpeptide inhibitor of human mast cell tryptase.
Experimental
Matched Description: … JNJ-27390467 is a potent, nonpeptide inhibitor of human mast cell tryptase. …

rAAV9-hNAGLU

rAAV9-hNAGLU consists of a recombinant AAV9 expressing human alpha-N-acetylglucosaminidase.
Investigational
Matched Description: … rAAV9-hNAGLU consists of a recombinant AAV9 expressing human alpha-N-acetylglucosaminidase. …

ZVS101e

ZVS101e is a recombinant adeno-associated virus vector carrying human CYP4V2 gene.
Investigational
Matched Description: … ZVS101e is a recombinant adeno-associated virus vector carrying human CYP4V2 gene. …

GIVI-MPC

GIVI-MPC is a therapy that uses human-induced pluripotent stem cell-derived myogenic progenitor cells.
Investigational
Matched Description: … GIVI-MPC is a therapy that uses human-induced pluripotent stem cell-derived myogenic progenitor cells …

Humanized monoclonal antibody Hu11E6

Investigational

CP-122721

CP-122721, neurokinin 1 (NK1) antagonist is developed by Pfizer to treat depression, emesis, and inflammatory diseases including asthma and irritable bowel syndrome.
Investigational
Matched Description: … diseases including asthma and irritable bowel syndrome. ... CP-122721, neurokinin 1 (NK1) antagonist is developed by Pfizer to treat depression, emesis, and inflammatory …

Thyrotropin

Thyrotropin is under investigation in clinical trial NCT01348191 (Detection of Thyrotrophin Receptor in Human Myometrium).
Investigational
Matched Description: … Thyrotropin is under investigation in clinical trial NCT01348191 (Detection of Thyrotrophin Receptor in Human …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Displaying drugs 1551 - 1575 of 1992 in total