Displaying drugs 1676 - 1700 of 1990 in total
RP-L301
RP-L301 is a lentiviral vector containing the human liver and erythroid pyruvate kinase gene.
Investigational
Matched Description: … RP-L301 is a lentiviral vector containing the human liver and erythroid pyruvate kinase gene. …
Zafiride
Zafiride is a human tumor necrosis factor coupled to the C terminus of CNGRCG peptide.
Investigational
Matched Description: … Zafiride is a human tumor necrosis factor coupled to the C terminus of CNGRCG peptide. …
LY2181308
LY2181308 is investigated in clinical trials for treating solid tumors. LY2181308 is a solid. LY2181308 is directed against a molecular target called survivin. LY2181308 is known to target baculoviral IAP repeat-containing protein 5. LY2181308 is an anti-sense oligonucleotide that potently downregulated survivin expression in human cancer cells derived from lung,...
Investigational
Matched Description: … cells derived from lung, colon, breast, prostate, ovary, cervix, skin and brain. ... LY2181308 is an anti-sense oligonucleotide that potently downregulated survivin expression in human cancer …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
ZYC300
ZYC300 is a plasmid DNA of CYP1B1 encapsulated in biodegradable poly-DL-lactide-coglycolide microparticles. It is designed as a vaccine, intended to increase immune system sensitivity to CYP1B1, an enzyme highly prevalent in tumor cells.
Investigational
jCell
jCell is an human retinal progenitor cell therapy for retinitis pigmentosa.
Investigational
Matched Description: … jCell is an human retinal progenitor cell therapy for retinitis pigmentosa. …
Garetosmab
Fibrodysplasia ossificans progressiva (FOP) is a rare autosomal dominant disorder of episodic, progressive heterotropic ossification. FOP is characterized by episodic inflammatory episodes, which may be precipitated by trauma, including immunizations and minor tissue damage, which usually result in ossification of the lesion. Patients experience abnormal cartilage formation, growth plate dysplasia,...
Investigational
Matched Description: … resulting in progressive immobility and associated comorbidities. ... [A242297] Patients experience abnormal cartilage formation, growth plate dysplasia, and joint issues, ... characterized by episodic inflammatory episodes, which may be precipitated by trauma, including immunizations and …
NVS antibody
This drug has been developed using Medarex's UltiMAb Human Antibody Development System to treat autoimmune diseases.
Investigational
Matched Description: … This drug has been developed using Medarex's UltiMAb Human Antibody Development System to treat autoimmune …
SB 224289
SB-224289 is a small molecule with a high affinity for human 5-HT1B receptors.
Investigational
Matched Description: … SB-224289 is a small molecule with a high affinity for human 5-HT1B receptors.[A253122] …
ZM-39923
ZM-39923 is a small molecule that inhibits Janus kinase and human tissue transglutaminase (TGM2).
Investigational
Matched Description: … ZM-39923 is a small molecule that inhibits Janus kinase and human tissue transglutaminase (TGM2). …
INO-4800
INO-4800 is a DNA vaccine containing the full sequence for the SARS-CoV-2 Spike (S) protein in development for immunization against COVID-19. Early in vitro studies using HEK-293T cells demonstrated that the transfection of INO-4800 results in the expression of S protein by human cells.[A214475, A214478] Follow up studies in both...
Investigational
Matched Description: … 293T cells demonstrated that the transfection of INO-4800 results in the expression of S protein by human ... of INO-4800 to induce both humoral and T cell-mediated immunity against SARS-CoV-2, including in the ... [A214475, A214478] Follow up studies in both BALB/c mice and Hartley guinea pigs demonstrated the ability …
Matched Categories: … Recombinant Proteins ... Amino Acids, Peptides, and Proteins …
Matched Categories: … Recombinant Proteins ... Amino Acids, Peptides, and Proteins …
Tosedostat
Tosedostat has been used in trials studying the treatment and supportive care of AML, Leukemia, Pancreas Cancer, Multiple Myeloma, and Pancreatic Cancer, among others.
Tosedostat is an inhibitor of the M1 family of aminopeptidases, in particular PuSA, and LTA4 hydrolase. It has demonstrated anti-tumour activity in a number of models...
Investigational
Matched Description: … Cancer, Multiple Myeloma, and Pancreatic Cancer, among others. ... in synergy with cytotoxic agents such as carboplatin and paclitaxel. ... Tosedostat has been used in trials studying the treatment and supportive care of AML, Leukemia, Pancreas …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
RP-A601
RP-A601 is an adeno-associated virus serotype rhesus 10 vector expressing the human galactocerebrosidase (GALC) gene
Investigational
Matched Description: … RP-A601 is an adeno-associated virus serotype rhesus 10 vector expressing the human galactocerebrosidase …
JNJ-27390467
JNJ-27390467 is a potent, nonpeptide inhibitor of human mast cell tryptase.
Experimental
Matched Description: … JNJ-27390467 is a potent, nonpeptide inhibitor of human mast cell tryptase. …
Genistein
An isoflavonoid derived from soy products. It inhibits protein-tyrosine kinase and topoisomerase-II (DNA topoisomerases, type II) activity and is used as an antineoplastic and antitumor agent. Experimentally, it has been shown to induce G2 phase arrest in human and murine cell lines.
Additionally, genistein has antihelmintic activity. It has been...
Investigational
Matched Description: … Experimentally, it has been shown to induce G2 phase arrest in human and murine cell lines. ... It inhibits protein-tyrosine kinase and topoisomerase-II (DNA topoisomerases, type II) activity and is ... used as an antineoplastic and antitumor agent. …
Matched Mixtures name: … CALCIDAY G 1200 MG/800 IU/50 MG EFERVESAN TABLET, 45 ADET ... CALCİDAY G 1000 MG/880 IU/50 MG EFERVESAN TABLET, 40 ADET …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Mixtures name: … CALCIDAY G 1200 MG/800 IU/50 MG EFERVESAN TABLET, 45 ADET ... CALCİDAY G 1000 MG/880 IU/50 MG EFERVESAN TABLET, 40 ADET …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
FCX-013
FCX-013 consists of human dermal fibroblasts genetically modified with a lentiviral vector expressing metalloproteinase-1 (MMP-1).
Investigational
Matched Description: … FCX-013 consists of human dermal fibroblasts genetically modified with a lentiviral vector expressing …
ATSN-101
ATSN-101 is a adeno-associated virus serotype 5 encoding human retinal guanylate cyclase 1 gene (AAV5-GUCY2D)
Investigational
Matched Description: … ATSN-101 is a adeno-associated virus serotype 5 encoding human retinal guanylate cyclase 1 gene (AAV5 …
TTAX01
TTAX01 is a cryopreserved human umbilical cord product being developed by TissueTech.
Investigational
Matched Description: … TTAX01 is a cryopreserved human umbilical cord product being developed by TissueTech.[L47246] …
VGB-R04
VGB-R04 is an adeno-associated viral vector delivering human FIX Padua gene.
Investigational
Matched Description: … VGB-R04 is an adeno-associated viral vector delivering human FIX Padua gene. …
Echinacoside
Echinacoside is a phenylethanoid glycoside isolated from Echinacea angustifolia in 1950, and currently being investigated for the treatment of Parkinson's, Alzheimer's, atherosclerosis, osteoporosis, acute colitis, wound treatment, and hepatitis. Echinacoside has demonstrated inhibition of apoptosis in neural cell lines, demonstrating potential for use in the treatment of neurological conditions.
Experimental
Matched Description: … Echinacoside is a phenylethanoid glycoside isolated from _Echinacea angustifolia_ in 1950, and currently ... treatment of Parkinson's, Alzheimer's, atherosclerosis, osteoporosis, acute colitis, wound treatment, and …
Matched Categories: … Herbs and Natural Products …
Matched Categories: … Herbs and Natural Products …
MRT5005
MRT5005 is a human cystic fibrosis transmembrane conductance regulator (hCFTR) messenger RNA (mRNA) complexed with branched polyethyleneimine (bPEI).
Investigational
Matched Description: … MRT5005 is a human cystic fibrosis transmembrane conductance regulator (hCFTR) messenger RNA (mRNA) complexed …
C134
C134 is a genetically engineered oncolytic herpes simplex virus expressing human cytomegalovirus (HCMV) internal repeat short 1 (IRS1).
Investigational
Matched Description: … C134 is a genetically engineered oncolytic herpes simplex virus expressing human cytomegalovirus (HCMV …
Alvespimycin
Alvespimycin is a derivative of geldanamycin and heat shock protein (HSP) 90 inhibitor. It has been used in trials studying the treatment of solid tumor in various cancer as an antitumor agent. In comparison to the first HSP90 inhibitor tanespimycin, it exhibits some pharmacologically desirable properties such as reduced metabolic...
Investigational
Matched Description: … Alvespimycin is a derivative of geldanamycin and heat shock protein (HSP) 90 inhibitor. ... plasma protein binding, increased water solubility, higher oral bioavailability, reduced hepatotoxicity and …
Indisulam
Investigational
Sennosides
Sennosides (also known as senna glycoside or senna) is a medication used to treat constipation[FDA Label] and empty the large intestine before surgery. The medication is taken by mouth or via the rectum[FDA Label]. It typically begins working in minutes when given by rectum and within twelve hours when given...
Experimental
Matched Description: … laxative medication, has recently proven effective in inhibiting the ribonuclease H (RNase H) activity of human ... also known as senna glycoside or senna) is a medication used to treat constipation[FDA Label][L771] and ... It typically begins working in minutes when given by rectum and within twelve hours when given by mouth …
Matched Mixtures name: … Senna and Docusate Sodium ... Senna and Docusate Sodium ... Docusate Sodium and Senna …
Matched Salts name: … Sennosides A and B …
Matched Categories: … Alimentary Tract and Metabolism ... Herbs and Natural Products …
Matched Mixtures name: … Senna and Docusate Sodium ... Senna and Docusate Sodium ... Docusate Sodium and Senna …
Matched Salts name: … Sennosides A and B …
Matched Categories: … Alimentary Tract and Metabolism ... Herbs and Natural Products …
Displaying drugs 1676 - 1700 of 1990 in total