Displaying drugs 1701 - 1725 of 1990 in total
SMART101
SMART101 is an investigational cell therapy comprising human allogeneic CD34-CD7+ T cell progenitors that were cultured ex vivo.
Investigational
Matched Description: … SMART101 is an investigational cell therapy comprising human allogeneic CD34-CD7+ T cell progenitors …
Viral Macrophage-Inflammatory Protein
Viral macrophage inflammatory protein-II (vMIP) is a highly basic protein and human chemokine analog encoded by human herpesvirus-8. The structure of vMIP consists of 71 residues and is a monomer under most conditions. It helps its virus evade the host immune system through selectively blocking and activating different receptors, preferentially...
Investigational
Matched Description: … Viral macrophage inflammatory protein-II (vMIP) is a highly basic protein and human chemokine analog ... encoded by human herpesvirus-8. ... The structure of vMIP consists of 71 residues and is a monomer under most conditions. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
MK-4721
MK-4721 is a fully human monoclonal antibody directed to Agensys’ proprietary target Prostate Stem Cell Antigen (PSCA), an antigen expressed at significant levels on tumor cells from the majority of patients with all stages of prostate, pancreatic and bladder cancers.
Investigational
Matched Description: … MK-4721 is a fully human monoclonal antibody directed to Agensys’ proprietary target Prostate Stem Cell ... significant levels on tumor cells from the majority of patients with all stages of prostate, pancreatic and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
M-2698
M-2698 is under investigation in clinical trial NCT01971515 (First-in-Human Dose Escalation Trial in Subjects With Advanced Malignancies).
Investigational
Matched Description: … M-2698 is under investigation in clinical trial NCT01971515 (First-in-Human Dose Escalation Trial in …
TSHA-105
TSHA-105 is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human SLC13A5 protein.
Investigational
Matched Description: … 105 is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human …
TRK-250
TRK-250 is a small interfering RNA agent that targets human transforming growth factor-beta 1 (TGF-β1) messenger RNA.
Investigational
Matched Description: … TRK-250 is a small interfering RNA agent that targets human transforming growth factor-beta 1 (TGF-β1 …
Tenofovir
Tenofovir is an acyclic nucleotide diester analog of adenosine monophosphate. In the most strict sense and due to the fact that it presents a phosphate group bound to the nitrogenous base, it is determined as an actual nucleotide analog. The antiviral activities of tenofovir were first reported in 1993 and...
Experimental
Investigational
Matched Description: … [A37693] In the most strict sense and due to the fact that it presents a phosphate group bound to the ... [A37693] The antiviral activities of tenofovir were first reported in 1993 and this agent was commercially ... available since 2008 in the form of [tenofovir disoproxil] and [tenofovir alafenamide] in order to obtain …
Matched Categories: … Tenofovir and prodrugs ... Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor …
Matched Categories: … Tenofovir and prodrugs ... Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor …
XTL-001
XTL001 is an investigational monoclonal antibody (MAb) product developed by XTL Biopharmaceuticals to evaluate the safety profile and antiviral activity of the compound in patients chronically infected with hepatitis B virus (HBV).
Investigational
Matched Description: … monoclonal antibody (MAb) product developed by XTL Biopharmaceuticals to evaluate the safety profile and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
PRGN-2012
PRGN-2012 is an adenoviral vector expressing human papillomavirus (HPV) 6 and HPV 11 antigens
Investigational
Matched Description: … PRGN-2012 is an adenoviral vector expressing human papillomavirus (HPV) 6 and HPV 11 antigens …
AAV-RPE65
AAV-RPE65 is an adenovirus associated viral vector serotype 5 containing the human RPE65 gene
Investigational
Matched Description: … AAV-RPE65 is an adenovirus associated viral vector serotype 5 containing the human RPE65 gene …
AAV-CNGB3
AAV-CNGB3 is an adenovirus associated viral vector serotype 8 containing the human CNGB3 gene.
Investigational
Matched Description: … AAV-CNGB3 is an adenovirus associated viral vector serotype 8 containing the human CNGB3 gene. …
mRNA-3745
mRNA-3745 is a lipid nanoparticle (LNP) encapsulated with nucleoside-modified, codon-optimized mRNAs encoding human glucose 6-phosphatase (G6Pase).
Investigational
Matched Description: … is a lipid nanoparticle (LNP) encapsulated with nucleoside-modified, codon-optimized mRNAs encoding human …
Troxacitabine
Troxacitabine is a nucleoside analog with antineoplastic activity. There has been growing interest in its development for the treatment of patients with refractory lymphoproliferative conditions.
Investigational
R1295
R1295 is an integrin antagonist currently in clinical trials for the treatment of rheumatoid arthritis. Integrins are associated to the pathology seen in some of the autoimmune diseases such as rheumatoid arthritis.
Investigational
IPH 2101
IPH-2101 (NN-1975), a fully human monoclonal antibody developed for patients with acute myeloid leukemia.
Investigational
Matched Description: … IPH-2101 (NN-1975), a fully human monoclonal antibody developed for patients with acute myeloid leukemia …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Dexelvucitabine
Dexelvucitabine has been used in trials studying the treatment of HIV Infections and Human Immunodeficiency Virus.
Investigational
Matched Description: … Dexelvucitabine has been used in trials studying the treatment of HIV Infections and Human Immunodeficiency …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Briakinumab
Briakinumab is a human anti-IL-12 monoclonal antibody being developed for the treatment of a number of T-cell driven autoimmune diseases. It targets and neutralize interleukin-12 and interleukin-23, two proteins associated with inflammation, such as pro-inflammatory interleukins or tumor necrosis factor- alpha. Briakinumab represents a novel approach to treating psoriasis, Multiple...
Investigational
Matched Description: … Briakinumab is a human anti-IL-12 monoclonal antibody being developed for the treatment of a number of ... It targets and neutralize interleukin-12 and interleukin-23, two proteins associated with inflammation ... other autoimmune and inflammatory disorders. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
LL-37
LL-37 is a human cathelicidin that inhibits viral replication and while also playing a role in host defense against infection.
Investigational
Matched Description: … LL-37 is a human cathelicidin that inhibits viral replication and while also playing a role in host defense …
TH0318
TH0318 is a stabilized analogue of human GLP-1 (glucagon-like peptide-1) under investigation for the treatment of type 2 diabetes.
Investigational
Matched Description: … TH0318 is a stabilized analogue of human GLP-1 (glucagon-like peptide-1) under investigation for the …
ABBV-011
ABBV-011 is an antibody-drug conjugate of humanized, cysteine-engineered IgG1 monoclonal antibody targeting seizure-related 6 homolog conjugated to N-acetyl-gamma-calicheamicin.
Investigational
FBX-101
FBX-101 is an adeno-associated virus serotype rhesus 10 vector expressing the human galactocerebrosidase (GALC) gene
Investigational
Matched Description: … FBX-101 is an adeno-associated virus serotype rhesus 10 vector expressing the human galactocerebrosidase …
Calpurbatug
Calpurbatug (TRL1068) is a high-affinity and broad-spectrum human antibody that targets and disintegrates bacterial biofilm.
Investigational
Matched Description: … Calpurbatug (TRL1068) is a high-affinity and broad-spectrum human antibody that targets and disintegrates …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
ARC-19499
ARC-19499 is under investigation in clinical trial NCT01191372 (First-in-Human and Proof-of-Mechanism Study of ARC19499 Administered to Hemophilia Patients).
Investigational
Matched Description: … ARC-19499 is under investigation in clinical trial NCT01191372 (First-in-Human and Proof-of-Mechanism …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Coltuximab ravtansine
Coltuximab ravtansine (SAR3419) targets CD19 and is being investigated for the treatment of acute lymphoblastic leukemia (ALL).
Investigational
Matched Description: … Coltuximab ravtansine (SAR3419) targets CD19 and is being investigated for the treatment of acute lymphoblastic …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Tipifarnib
Tipifarnib (R-115777) is a substance that is being studied in the treatment of acute myeloid leukemia (AML) and other types of cancer. It belongs to the family of drugs called farnesyltransferase inhibitors. It is also called Zarnestra. In June 2005, the FDA issued a Not Approvable Letter for Zarnestra.
Investigational
Matched Description: … Tipifarnib (R-115777) is a substance that is being studied in the treatment of acute myeloid leukemia (AML) and …
Displaying drugs 1701 - 1725 of 1990 in total