Displaying drugs 1801 - 1825 of 2325 in total
Mitiperstat
Mitiperstat is under investigation in clinical trial NCT05492877 (An Efficacy and Safety Study of Mitiperstat (AZD4831) (MPO Inhibitor) vs Placebo in the Treatment of Moderate to Severe COPD.).
Investigational
Matched Synonyms: … 1-({2-[(1R)-1-aminoethyl]-4-chlorophenyl}methyl)-2-sulfanylidene-1,2,3,5-tetrahydro-4H-pyrrolo[3,2-d] ... 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 1-[[2-[(1R)-1-aminoethyl]-4-chlorophenyl]methyl]-1,2,3,5-tetrahydro …
Matched Description: … Mitiperstat is under investigation in clinical trial NCT05492877 (An Efficacy and Safety Study of Mitiperstat …
Matched Description: … Mitiperstat is under investigation in clinical trial NCT05492877 (An Efficacy and Safety Study of Mitiperstat …
MB07133
Investigational
Matched Synonyms: … -d-arabinofuranosyl)- ... -d-arabinofuranosyl)-2(1h)-pyrimidinone ... (2R,4S)-4-amino-1-(5-O-(2-oxo-4-(4-pyridyl)-1,3,2-dioxaphosphorinan-2-yl)-beta-d-arabinofuranosyl)-2( …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
3-(4-(1,5-Naphthyridine)imidazole(1,2-a) pyridine-7-(1-phenyl-4-(1-(4-methyl piperazine)))
Investigational
Matched Synonyms: … 3-(4-(1,5-napthrydine)imidazole(1,2-a)pyridine-7-(1-phenyl-4-(1-(4-methyl piperazine))) …
Matched Name: … 3-(4-(1,5-Naphthyridine)imidazole(1,2-a) pyridine-7-(1-phenyl-4-(1-(4-methyl piperazine))) …
Matched Name: … 3-(4-(1,5-Naphthyridine)imidazole(1,2-a) pyridine-7-(1-phenyl-4-(1-(4-methyl piperazine))) …
METHYL(2-ACETOXY-2-(2-CARBOXY-4-AMINO-PHENYL))ACETATE
Experimental
Matched Name: … METHYL(2-ACETOXY-2-(2-CARBOXY-4-AMINO-PHENYL))ACETATE …
Desipramine
Desipramine hydrochloride is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, desipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, desipramine exerts a positive...
Approved
Investigational
Matched Synonyms: … DMI …
Matched Description: … TCAs also block histamine-H1 receptors, α1-adrenergic receptors and muscarinic ... Desipramine hydrochloride is a dibenzazepine-derivative tricyclic antidepressant (TCA). ... vision, dry mouth, constipation, urinary retention), respectively. …
Matched Salts name: … Desipramine hydrochloride …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors …
Matched Products: … Desipramine Hydrochloride ... Dom-desipramine Tablets - 50mg ... Dom-desipramine Tablets - 25mg …
Matched Description: … TCAs also block histamine-H1 receptors, α1-adrenergic receptors and muscarinic ... Desipramine hydrochloride is a dibenzazepine-derivative tricyclic antidepressant (TCA). ... vision, dry mouth, constipation, urinary retention), respectively. …
Matched Salts name: … Desipramine hydrochloride …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors …
Matched Products: … Desipramine Hydrochloride ... Dom-desipramine Tablets - 50mg ... Dom-desipramine Tablets - 25mg …
6-methyl-formycin A
Experimental
Matched Synonyms: … 2-(7-amino-6-methyl-3H-pyrazolo[4,3-d]pyrimidin-3-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol …
Matched Iupac: … 7-amino-3-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-methyl-2H-pyrazolo[4,3-d]pyrimidin …
Matched Iupac: … 7-amino-3-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-methyl-2H-pyrazolo[4,3-d]pyrimidin …
SNS-314
SNS-314 is a potent and selective inhibitor of Aurora kinases A, B, and C. Proliferating cells treated with SNS-314 bypass the mitotic spindle checkpoint and fail to undergo cytokinesis, leading to multiple rounds of endoreduplication and eventually cell death. SNS-314 inhibits tumor growth in a variety of preclinical models, and...
Investigational
Matched Synonyms: … 1-(3-chlorophenyl)-3-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl}urea …
Matched Iupac: … 1-(3-chlorophenyl)-3-{5-[2-({thieno[3,2-d]pyrimidin-4-yl}amino)ethyl]-1,3-thiazol-2-yl}urea …
Matched Description: … SNS-314 is a potent and selective inhibitor of Aurora kinases A, B, and C. ... , leading to multiple rounds of endoreduplication and eventually cell death. ... Proliferating cells treated with SNS-314 bypass the mitotic spindle checkpoint and fail to undergo cytokinesis …
Matched Iupac: … 1-(3-chlorophenyl)-3-{5-[2-({thieno[3,2-d]pyrimidin-4-yl}amino)ethyl]-1,3-thiazol-2-yl}urea …
Matched Description: … SNS-314 is a potent and selective inhibitor of Aurora kinases A, B, and C. ... , leading to multiple rounds of endoreduplication and eventually cell death. ... Proliferating cells treated with SNS-314 bypass the mitotic spindle checkpoint and fail to undergo cytokinesis …
Ilacirnon
Ilacirnon (CCX-140) is under investigation in clinical trial NCT01440257 (A Study to Evaluate the Effect of CCX140-B on Urinary Albumin Excretion in Subjects With Type 2 Diabetes and Albuminuria).
Investigational
Matched Synonyms: … 4-Chloro-N-[5-methyl-2-(7H-pyrrolo[2,3-d]pyrimidin-4-ylcarbonyl)-3-pyridinyl]-3-(trifluoromethyl)benzenesulfonamide …
Matched Iupac: … 4-chloro-N-(5-methyl-2-{7H-pyrrolo[2,3-d]pyrimidine-4-carbonyl}pyridin-3-yl)-3-(trifluoromethyl)benzene …
Matched Description: … Study to Evaluate the Effect of CCX140-B on Urinary Albumin Excretion in Subjects With Type 2 Diabetes and …
Matched Salts name: … Ilacirnon sodium …
Matched Iupac: … 4-chloro-N-(5-methyl-2-{7H-pyrrolo[2,3-d]pyrimidine-4-carbonyl}pyridin-3-yl)-3-(trifluoromethyl)benzene …
Matched Description: … Study to Evaluate the Effect of CCX140-B on Urinary Albumin Excretion in Subjects With Type 2 Diabetes and …
Matched Salts name: … Ilacirnon sodium …
PD173955
Experimental
Matched Synonyms: … 6-(2,6-dichlorophenyl)-8-methyl-2-{[3-(methylthio)phenyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one …
Matched Iupac: … 6-(2,6-dichlorophenyl)-8-methyl-2-{[3-(methylsulfanyl)phenyl]amino}-7H,8H-pyrido[2,3-d]pyrimidin-7-one …
Matched Iupac: … 6-(2,6-dichlorophenyl)-8-methyl-2-{[3-(methylsulfanyl)phenyl]amino}-7H,8H-pyrido[2,3-d]pyrimidin-7-one …
3-[2,6,8-Trioxo-9-[(2R,3R,4R)-2,3,4,5-tetrahydroxypentyl]-3H-purin-7-yl]propyl dihydrogen phosphate
Experimental
Matched Synonyms: … 5-Deoxy-5-{2,6,8-trioxo-7-[3-(phosphonooxy)propyl]-1,2,3,6,7,8-hexahydro-9H-purin-9-yl}-D-arabinitol …
Calusterone
A 17-alkylated orally active androgenic steroid. A Schedule IV drug in Canada.
Experimental
Illicit
Matched Synonyms: … 7-beta,17-alpha-Dimethyl testosterone ... 17-beta-Hydroxy-7-beta,17-alpha-dimethylandrost-4-ene-3-one …
Matched Categories: … Testosterone and derivatives …
Matched Categories: … Testosterone and derivatives …
Histidine
An essential amino acid that is required for the production of histamine.
Investigational
Nutraceutical
Matched Synonyms: … (S)-alpha-amino-1H-Imidazole-4-propanoic acid ... (S)-alpha-Amino-1H-imidazole-4-propionic acid …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Aminosyn II with Electrolytes in Dextrose with Calcium …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Aminosyn II with Electrolytes in Dextrose with Calcium …
Matched Categories: … Amino Acids, Peptides, and Proteins …
TAK-733
TAK-733 has been used in trials studying the treatment of Advanced Metastatic Melanoma, Advanced Nonhematologic Malignancies, and Advanced Non-hematologic Malignancies.
Investigational
Matched Synonyms: … (R)-3-(2,3-DIHYDROXYPROPYL)-6-FLUORO-5-(2-FLUORO-4-IODOPHENYLAMINO)-8-METHYLPYRIDO(2,3-D)PYRIMIDINE-4,7 ... 3-[(2R)-2,3-dihydroxypropyl]-6-fluoro-5-[(2-fluoro-4-iodophenyl)amino]-8-methylpyrido[2,3-d]pyrimidine …
Matched Iupac: … (2R)-2,3-dihydroxypropyl]-6-fluoro-5-[(2-fluoro-4-iodophenyl)amino]-8-methyl-3H,4H,7H,8H-pyrido[2,3-d] …
Matched Description: … trials studying the treatment of Advanced Metastatic Melanoma, Advanced Nonhematologic Malignancies, and …
Matched Iupac: … (2R)-2,3-dihydroxypropyl]-6-fluoro-5-[(2-fluoro-4-iodophenyl)amino]-8-methyl-3H,4H,7H,8H-pyrido[2,3-d] …
Matched Description: … trials studying the treatment of Advanced Metastatic Melanoma, Advanced Nonhematologic Malignancies, and …
Inavolisib
Inavolisib (GDC-0077) is under investigation in clinical trial NCT03006172 (To Evaluate the Safety, Tolerability, and Pharmacokinetics of GDC-0077 Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer).
Investigational
Matched Synonyms: … (2S)-2-((2-((4S)-4-(difluoromethyl)-2-oxo-3-oxazolidinyl)-5,6-dihydroimidazo(1,2-D)(1,4)benzoxazepin- ... propanamide, 2-((2-((4S)-4-(difluoromethyl)-2-oxo-3-oxazolidinyl)-5,6-dihydroimidazo(1,2-D)(1,4)benzoxazepin …
Matched Description: … Endocrine and Targeted Therapies in Participants With Breast Cancer). ... GDC-0077) is under investigation in clinical trial NCT03006172 (To Evaluate the Safety, Tolerability, and ... Pharmacokinetics of GDC-0077 Single Agent in Participants With Solid Tumors and in Combination With …
Matched Description: … Endocrine and Targeted Therapies in Participants With Breast Cancer). ... GDC-0077) is under investigation in clinical trial NCT03006172 (To Evaluate the Safety, Tolerability, and ... Pharmacokinetics of GDC-0077 Single Agent in Participants With Solid Tumors and in Combination With …
Olpasiran
Olpasiran is under investigation in clinical trial NCT05581303 (Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction (Ocean(a)) - Outcomes Trial).
Investigational
Matched Synonyms: … -D-GALACTOPYRANOSYL)OXY)-25,30-BIS((2-(2-((2-ACETAMIDO-2-DEOXY-.BETA. ... -D-GALACTOPYRANOSYL)OXY)ETHOXY)ETHYL)CARBAMOYL)-1,23,28,33-TETRAOXO-1-SULFANYL-2,5,8,11,14,17,20,37-OCTAOXA …
Matched Description: … Olpasiran is under investigation in clinical trial NCT05581303 (Olpasiran Trials of Cardiovascular Events and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Description: … Olpasiran is under investigation in clinical trial NCT05581303 (Olpasiran Trials of Cardiovascular Events and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Vilamakitug
Vilamakitug is under investigation in clinical trial NCT05201352 (Evaluation of Efficacy of Trifluridine/tipiracil Plus an Anti-il-1α True Human Antibody Versus Trifluridine/tipiracil Plus Placebo in Metastatic Colorectal Cancer Patients After Failure of Oxaliplatin, Irinotecan, Fluoropyrimidine).
Investigational
Matched Synonyms: … Immunoglobulin g4, anti-(human interleukin 1.alpha.) …
Dexamethasone palmitate
Dexamethasone palmitate is under investigation in clinical trial NCT05693467 (Preemptive Co-infiltration of Dexamethasone Palmitate With Ropivacaine for Postoperative Pain in Major Spinal Surgery).
Investigational
Matched Synonyms: … .,16.alpha.)- …
AR-42
AR-42 has been used in trials studying the treatment of Meningioma, Acoustic Neuroma, Testicular Lymphoma, Intraocular Lymphoma, and Vestibular Schwannoma, among others.
Investigational
Matched Synonyms: … BENZENEACETAMIDE, N-(4-((HYDROXYAMINO)CARBONYL)PHENYL)-.ALPHA.-(1-METHYLETHYL)-, (.ALPHA.S)- …
Matched Description: … studying the treatment of Meningioma, Acoustic Neuroma, Testicular Lymphoma, Intraocular Lymphoma, and …
Matched Description: … studying the treatment of Meningioma, Acoustic Neuroma, Testicular Lymphoma, Intraocular Lymphoma, and …
N-(R-Carboxy-Ethyl)-Alpha-(S)-(2-Phenylethyl)
Experimental
Matched Name: … N-(R-Carboxy-Ethyl)-Alpha-(S)-(2-Phenylethyl) …
Matched Iupac: … -[(1H-imidazol-2-yl)methyl]piperidin-4-yl}-1-(4-pentylphenyl)formamido)methyl]-[1,1'-biphenyl]-4-yl}acetate …
Matched Iupac: … -[(1H-imidazol-2-yl)methyl]piperidin-4-yl}-1-(4-pentylphenyl)formamido)methyl]-[1,1'-biphenyl]-4-yl}acetate …
ORC-13661
ORC-13661 is under investigation in clinical trial NCT05730283 (Prevention of Ototoxicity in NTM Patients Treated With IV Amikacin).
Investigational
Matched Synonyms: … 4R,6S)-2-[[[(4-Chlorophenyl)amino]carbonyl]amino]-4,5,6,7-tetrahydro-5-methyl-4,6-ethanothieno[3,2-c]pyridine ... 4,6-Ethanothieno[3,2-c]pyridine-3-carboxamide, 2-[[[(4-chlorophenyl)amino]carbonyl]amino]-4,5,6,7-tetrahydro …
FDL169
Investigational
Matched Synonyms: … 2-(7-ethoxy-4-(3-fluorophenyl)-1-oxophthalazin-2(1H)-yl)-N-methyl-N-(2-methylbenzo(D)oxazol-6-yl)acetamide ... 2-(7-ethoxy-4-(3-fluorophenyl)-1-oxophthalazin-2(1H)-yl)-N-methyl-N-(2-methylbenzo[D]oxazol-6-yl)acetamide …
Epicaptopril
Experimental
Matched Synonyms: … 2-D-Methyl-3-mercaptopropanoyl-L-proline …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
(+)-menthol
Experimental
Matched Synonyms: … D-menthol …
Matched Mixtures name: … DR JOE LAB PMS Menstrual Pain Relief Cream DR JOE LAB ... DR JOE LAB PMS Menstrual Pain Relief Cream DR JOE LAB …
Matched Mixtures name: … DR JOE LAB PMS Menstrual Pain Relief Cream DR JOE LAB ... DR JOE LAB PMS Menstrual Pain Relief Cream DR JOE LAB …
Modufolin
Modufolin is under investigation for the treatment of Osteosarcoma.
Investigational
Matched Synonyms: … D-N5,N10-METHYLENE-L-TETRAHYDROFOLIC ACID …
1-(5-phospho-D-ribosyl)-ATP
Experimental
Matched Name: … 1-(5-phospho-D-ribosyl)-ATP …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Displaying drugs 1801 - 1825 of 2325 in total