Displaying drugs 1801 - 1825 of 1870 in total
GTP-506
GTP-506 is a gene therapy formed by two vectors, a nuclease vector targeting gene editing in the well-characterized PCSK9 gene locus and a therapeutic donor vector that inserts the OTC gene to provide the desired genetic correction.
Investigational
Matched Synonyms: … Non-replicating recombinant adeno-associated virus serotype rh79 (AAVrh.79) vectors: AAVrh79.TBG.M2PCSK9.WPRE.bGH and …
Matched Description: … by two vectors, a nuclease vector targeting gene editing in the well-characterized PCSK9 gene locus and …
Matched Description: … by two vectors, a nuclease vector targeting gene editing in the well-characterized PCSK9 gene locus and …
Delolimogene mupadenorepvec
Investigational
Matched Synonyms: … Dna (synthetic human adenovirus 5/35 vector load703 human cd137 ligand and trimerized membrane-bound …
Tezacitabine
A synthetic purine nucleoside analogue with potential antineoplastic activity.
Investigational
Matched Salts name: … Tezacitabine monohydrate …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Acrylic Acid
A α,β-unsaturated monocarboxylic acid that is ethene substituted by a carboxy group.
Experimental
Matched Salts name: … Sodium acrylate …
Matched Categories: … Equipment and Supplies …
Matched Categories: … Equipment and Supplies …
Tuspetinib
Tuspetinib (HM-43239) is under investigation in clinical trial NCT03850574 (Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HM43239 in Patients With Relapsed or Refractory Acute Myeloid Leukemia).
Investigational
Matched Description: … in clinical trial NCT03850574 (Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and …
Matched Salts name: … Tuspetinib monohydrate …
Matched Salts name: … Tuspetinib monohydrate …
Azercabtagene zapreleucel
Investigational
Matched Synonyms: … Adult allogeneic CD4+ and CD8+ enriched T cells, gene edited through the electroporati ... Adult allogeneic CD4+ and CD8+ enriched T cells transduced with an anti-CD19 chimeric antigen receptor …
Pinometostat
Pinometostat has been used in trials studying the treatment of Leukemia, Acute Leukemias, Acute Myeloid Leukemia, Myelodysplastic Syndrome, and Acute Lymphocytic Leukemia, among others.
Investigational
Matched Synonyms: … PINOMETOSTAT ANHYDROUS …
Matched Description: … studying the treatment of Leukemia, Acute Leukemias, Acute Myeloid Leukemia, Myelodysplastic Syndrome, and …
Matched Description: … studying the treatment of Leukemia, Acute Leukemias, Acute Myeloid Leukemia, Myelodysplastic Syndrome, and …
Suratadenoturev
Suratadenoturev is a gene-modified oncolytic adenovirus expressing the telomerase reverse transcriptase gene.
Investigational
Matched Synonyms: … telomerase reverse transcriptase (hTERT) and IRES, respectively. ... -5) in which the E1 gene, including its normal transcriptional regulatory element, has been deleted and ... A replication-competent adenovirus type 5 in which the E1A and E1B genes are under the control of a human …
Ozagrel
Ozagrel has been used in trials studying the treatment of Dry Eye Syndromes.
Investigational
Matched Salts name: … Ozagrel Sodium …
Tepilamide fumarate
Investigational
Matched Synonyms: … 2-(diethylamino)-2-oxoethyl and methyl (2e)-but-2-enedioate …
Lawsonia inermis leaf
Lawsonia inermis leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Plants and Plant Parts, Henna Lawsonia Inermis …
OTL-102
OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human gp91phox gene. It is being investigated for the treatment of X-linked chronic granulomatous disease.
Investigational
Matched Synonyms: … Autologous CD34+ enriched cell population that contains hematopoietic stem and progenitor cells transduced …
Matched Description: … OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells …
Matched Description: … OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells …
ATX-101
ATX-101 (medical), sodium deoxycholate for subcutaneous injection, is being evaluated as a treatment for the reduction of localized fat deposits. This includes treatment of superficial lipomas (benign tumors of soft tissue composed of mature fat cells), fat deposits in the submental region of the face/neck, and localized fat deposits in...
Investigational
Matched Description: … ATX-101 (medical), sodium deoxycholate for subcutaneous injection, is being evaluated as a treatment ... of soft tissue composed of mature fat cells), fat deposits in the submental region of the face/neck, and …
Quinacrine
An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
Investigational
Matched Description: … It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Butylidenephthalide
Investigational
Matched Synonyms: … 3-butylidenephthalide, mixture of cis and trans isomers …
TBC-3711
TBC3711 is a next-generation endothelin antagonist that is being studied through oral and intravenous formulations by Encysive Pharmaceuticals.
Investigational
Matched Description: … TBC3711 is a next-generation endothelin antagonist that is being studied through oral and intravenous …
Emeramide
Emeramide has been used in trials studying the treatment of Mercury Poisoning.
Investigational
Matched Salts name: … Emeramide Sodium …
Volixibat
Volixibat, also known as SHP626 or LUM002, is an investigational drug that will potentially be used for the treatment of Non-Alcoholic Steatohepatitis (NASH). If approved for use, it will be the first available agent for the treatment of NASH.
Volixibat is a selective inhibitor of the apical sodium-dependent bile acid...
Experimental
Investigational
Matched Description: … Volixibat is a selective inhibitor of the apical sodium-dependent bile acid transporter (ASBT), a transmembrane ... ultimately for hepatic lipid and glucose metabolism [A32120]. ... transporter (IBAT), ASBT is primarily responsible for the enterohepatic recirculation of bile acids and …
Hyperforin
Hyperforin is a phytochemical generated by the plants of the Hypericum family. One of the most important members of this family, due to its medical properties, is Hypericum perforatum, also known as St John's wort.
Nutraceutical
Isatoribine
Isatoribine is a selective agonist of TLR7.
Investigational
Matched Salts name: … Isatoribine monohydrate …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
PRGN-3006
PRGN-3006 are autologous CD3+ T cells genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and a truncated form of human HER1T (kill switch) on the cell surface.
Investigational
Matched Synonyms: … genetically modified using a non-viral system to express a CD33 CAR, membrane bound Interleukin-15, and …
Matched Description: … genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and …
Matched Description: … genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and …
Rolofylline
Rolofylline is under clinical development by pharmaceutical company NovaCardia for the treatment of congestive heart failure.
Investigational
NKX101
NKX101 is an investigational allogeneic chimeric antigen receptor (CAR)-natural killer cell therapy.
Investigational
Matched Synonyms: … NK) cell therapy engineered with an NKG2D ACR, OX40 costimulatory domain, CD3zeta signaling moiety, and …
Tetraethylammonium
Tetraethylammonium is an experimental drug with no approved indication or marketed formulation. The only marketed drug containing tetraethylammonium was a combination drug called Fosglutamina B6, but this drug has now been discontinued. As an experimental agent, tetraethylammonium is used in its salt forms such as tetraethylammonium chloride and tetraethylammonium bromide....
Experimental
Investigational
Matched Description: … voltage- activated potassium channels, and nicotinic acetylcholine receptors. ... experimental agent, tetraethylammonium is used in its salt forms such as tetraethylammonium chloride and ... still being investigated, but it is known that tetraethylammonium blocks autonomic ganglia, calcium- and …
Matched Salts name: … Tetraethylammonium phosphate …
Matched Salts name: … Tetraethylammonium phosphate …
Displaying drugs 1801 - 1825 of 1870 in total