Pinometostat

DB12920InvestigationalSmall molecule

Pinometostat has been used in trials studying the treatment of Leukemia, Acute Leukemias, Acute Myeloid Leukemia, Myelodysplastic Syndrome, and Acute Lymphocytic Leukemia, among others.

Formula / weight: C₃₀H₄₂N₈O₃ · 562.7063 g/mol (avg)
Also known as: 9H-PURIN-6-AMINE, 9-(5-DEOXY-5-((CIS-3-(2-(6-(1,1-DIMETHYLETHYL)-1H-BENZIMIDAZOL-2-YL)ETHYL)CYCLOBUTYL)(1-METHYLETHYL)AMINO)-.BETA.-D-RIBOFURANOSYL)- · PINOMETOSTAT ANHYDROUS
Code names: EPZ-005676 · EPZ-5676

Resolves to

Compound

UNII8V9YR09EF3CAS1380288-87-8ChEMBLCHEMBL3414626PubChem57345410

Structure

InChIKeyLXFOLMYKSYSZQS-LURJZOHASA-NSMILES

[H][C@]1(CCC2=NC3=C(N2)C=C(C=C3)C(C)(C)C)C[C@]([H])(C1)N(C[C@@]1([H])O[C@@]([H])(N2C=NC3=C(N)N=CN=C23)[C@]([H])(O)[C@]1([H])O)C(C)C

Targets

Q8TEK3DOT1L

What you can answer from here — as of April 23, 2025

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

39Drug interactionsStructured to mechanism, not free text

4Clinical trialsPhase, status and sponsor resolved per trial

1+ReferenceStructured and connected to the statements they support

Which drugs share a target with Pinometostat, and which of those have an active Phase 3 trial?

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