Displaying drugs 1926 - 1931 of 1931 in total
Bavituximab
Bavituximab is a chimeric Anti-PS monoclonal antibody analog which is used to potentially treat cancers and viral infections. It binds to phosphatidylserine and other exposed host cell lipids when induced by cellular stress. Additional analogs in the class include 3G4, 2aG4, 9d2 and Hu3g4.
Investigational
Matched Description: … Additional analogs in the class include 3G4, 2aG4, 9d2 and Hu3g4. ... It binds to phosphatidylserine and other exposed host cell lipids when induced by cellular stress. ... Bavituximab is a chimeric Anti-PS monoclonal antibody analog which is used to potentially treat cancers and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Droloxifene
Droloxifene, a derivative of the triphenylethylene drug tamoxifen, is a novel selective estrogen receptor modulator (SERM). Droloxifene also exhibits more rapid pharmacokinetics, reaching peak concentrations and being eliminated much more rapidly than tamoxifen. Its higher affinity to the estrogen receptor, higher anti-estrogenic to estrogenic ratio, more effective inhibition of cell...
Investigational
Matched Description: … over tamoxifen in the treatment of human breast cancer. ... Droloxifene appears active and tolerable. ... Droloxifene may have an effect on bone and breast tissue because it induces apoptosis. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Umbilical Cord Blood Hematopoietic Stem Cells
The use of umbilical cord blood (UCB) for therapies is advantageous because of its ease of access, non-invasive collection procedures, and more plasticity for multi-differentiation. UCB contains a large source of hematopoietic stem cells (HSCs) that are capable of self-renewal, have increased sensitivity to various factors, and are able to...
Investigational
Matched Description: … Specifically, the proliferation capacity of human umbilical cord blood mononuclear progenitor cells ( ... From the UCB, mononuclear cells are isolated and cultured in medium, expanded, and differentiated into ... of cytotoxicity and immunological reactions. …
Isoflavone
Isoflavone is a soy phytoestrogen and a biologically active component of several agriculturally important legumes such as soy, peanut, green peas, chick peas and alfalfa . Soybean is an exceptionally rich source of dietary isoflavones, where the average isoflavone content is 1-2 mg/gram . The main soy isoflavones are mostly...
Experimental
Matched Description: … The main soy isoflavones are mostly present in glycosylated forms and include [DB01645], [DB13182], and ... breast and prostate cancer [A33099]. ... legumes such as soy, peanut, green peas, chick peas and alfalfa [A33103]. …
Methoxyamine
Investigational
Cannabidivarin
Cannabidivarin, also known as cannabidivarol or CBDV, is a non-psychoactive cannabinoid found within DB14009. It is one of over 100 cannabinoids identified from the Cannabis plant that can modulate the physiological activity of cannabis, or marijuana . Compared to its homolog, DB09061, CBDV is shortened by two methyl (CH2) groups...
Investigational
Matched Description: … Notably, both [DB09061] and CBDV have demonstrated anticonvulsant activity in animal and human models ... CBD and CBDV have been shown to dose-dependently activate and then desensitize TRPV1 as well as TRPV2 ... and TRPA1 channels [A31560, A33334, A32976]. …
Displaying drugs 1926 - 1931 of 1931 in total