Displaying drugs 2101 - 2125 of 8940 in total
AZD2066
Investigational
Matched Synonyms: … Pyridine, 4-(5-((1r)-1-(5-(3-chlorophenyl)-3-isoxazolyl)ethoxy)-4-methyl-4h-1,2,4-triazol-3-yl)- …
Matched Iupac: … 4-{5-[(1R)-1-[5-(3-chlorophenyl)-1,2-oxazol-3-yl]ethoxy]-4-methyl-4H-1,2,4-triazol-3-yl}pyridine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 4-{5-[(1R)-1-[5-(3-chlorophenyl)-1,2-oxazol-3-yl]ethoxy]-4-methyl-4H-1,2,4-triazol-3-yl}pyridine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
JQ1
First-in-class potent and selective inhibitor of the BRD4 signaling pathway.
Investigational
Matched Synonyms: … (s)-(+)-tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin ... Tert-butyl 2-((6s)-4-(4-chlorophenyl)-2,3,9-trimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin ... 6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine-6-acetic acid, 4-(4-chlorophenyl)-2,3,9-trimethyl …
Matched Iupac: … tert-butyl 2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0^{2,6 ... }]trideca-2(6),4,7,10,12-pentaen-9-yl]acetate …
Matched Iupac: … tert-butyl 2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0^{2,6 ... }]trideca-2(6),4,7,10,12-pentaen-9-yl]acetate …
1-[5-Methyl-2-(trifluoromethyl)furan-3-yl]-3-[5-[2-[[6-(1H-1,2,4-triazol-5-ylamino)pyrimidin-4-yl]amino]ethyl]-1,3-thiazol-2-yl]urea
Experimental
Matched Name: … 1-[5-Methyl-2-(trifluoromethyl)furan-3-yl]-3-[5-[2-[[6-(1H-1,2,4-triazol-5-ylamino)pyrimidin-4-yl]amino ... ]ethyl]-1,3-thiazol-2-yl]urea …
Matched Iupac: … 3-[5-methyl-2-(trifluoromethyl)furan-3-yl]-1-{5-[2-({6-[(1H-1,2,4-triazol-5-yl)amino]pyrimidin-4-yl}amino ... )ethyl]-1,3-thiazol-2-yl}urea …
Matched Iupac: … 3-[5-methyl-2-(trifluoromethyl)furan-3-yl]-1-{5-[2-({6-[(1H-1,2,4-triazol-5-yl)amino]pyrimidin-4-yl}amino ... )ethyl]-1,3-thiazol-2-yl}urea …
5-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1H-1,2,4-TRIAZOLE-3-SULFONAMIDE
Experimental
Matched Name: … 5-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1H ... -1,2,4-TRIAZOLE-3-SULFONAMIDE …
Matched Iupac: … 5-(5-chlorothiophen-2-yl)-N-[(3S)-1-[(2S)-1-(morpholin-4-yl)-1-oxopropan-2-yl]-2-oxopyrrolidin-3-yl]- ... 1H-1,2,4-triazole-3-sulfonamide …
Matched Iupac: … 5-(5-chlorothiophen-2-yl)-N-[(3S)-1-[(2S)-1-(morpholin-4-yl)-1-oxopropan-2-yl]-2-oxopyrrolidin-3-yl]- ... 1H-1,2,4-triazole-3-sulfonamide …
Lorundrostat
Lorundrostat is under investigation in clinical trial NCT06153693 (Efficacy and Safety of Lorundrostat in Subjects With Uncontrolled and Resistant Hypertension).
Investigational
Matched Synonyms: … N-(trans-4-acetamidocyclohexyl)-2-{4-[5-(4-methylphenyl)-1,2,4-triazin-3-yl]piperazin-1-yl}acetamide ... 1-Piperazineacetamide, N-[trans-4-(acetylamino)cyclohexyl]-4-[5-(4-methylphenyl)-1,2,4-triazin-3-yl]- …
Obeldesivir
Investigational
Matched Synonyms: … 2-C-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-D -altrononitrile 6-(2-methylpropanoate) ... D-Altrononitrile, 2-C-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-, 6-(2-methylpropanoate) ... ((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
(2S,3S)-3-AMINO-4-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-5-YLCYCLOHEXYL)BUTANAMIDE
Experimental
Matched Name: … (2S,3S)-3-AMINO-4-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A] …
Matched Iupac: … (2S,3S)-3-amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-4-oxo-2-[(1r,4S)-4-{[1,2,4]triazolo[1,5 …
Matched Iupac: … (2S,3S)-3-amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-N,N-dimethyl-4-oxo-2-[(1r,4S)-4-{[1,2,4]triazolo[1,5 …
5,6-Dihydro-Benzo[H]Cinnolin-3-Ylamine
Experimental
Matched Name: … 5,6-Dihydro-Benzo[H]Cinnolin-3-Ylamine …
(2S,3S)-4-cyclopropyl-3-{(3R,5R)-3-[2-fluoro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazolidin-5-yl}-1-[(3S)-3-fluoropyrrolidin-1-yl]-1-oxobutan-2-amine
Experimental
Matched Name: … (2S,3S)-4-cyclopropyl-3-{(3R,5R)-3-[2-fluoro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazolidin-5-yl}-1-[( ... 3S)-3-fluoropyrrolidin-1-yl]-1-oxobutan-2-amine …
Matched Iupac: … (2S,3S)-2-amino-4-cyclopropyl-3-[(3R)-3-(2-fluoro-4-methanesulfonylphenyl)-1,2,4-oxadiazolidin-5-yl]- ... 1-[(3S)-3-fluoropyrrolidin-1-yl]butan-1-one …
Matched Iupac: … (2S,3S)-2-amino-4-cyclopropyl-3-[(3R)-3-(2-fluoro-4-methanesulfonylphenyl)-1,2,4-oxadiazolidin-5-yl]- ... 1-[(3S)-3-fluoropyrrolidin-1-yl]butan-1-one …
3,5-Dihydro-5-Methylidene-4h-Imidazol-4-On
Experimental
Matched Name: … 3,5-Dihydro-5-Methylidene-4h-Imidazol-4-On …
Matched Iupac: … 2-[(2S,4S)-2-[(1S)-1-aminoethyl]-4-(aminomethyl)-5-oxoimidazolidin-1-yl]acetic acid …
Matched Iupac: … 2-[(2S,4S)-2-[(1S)-1-aminoethyl]-4-(aminomethyl)-5-oxoimidazolidin-1-yl]acetic acid …
Bemcentinib
Bemcentinib has been investigated for the treatment of Non-Small Cell Lung Cancer.
Investigational
Matched Synonyms: … -5H-benzo[7]annulen-2-yl)-1H-1,2,4-triazole-3,5-diamine ... (S)-1-(6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N3-(7-(pyrrolidin-1-yl)- 6,7,8,9-tetrahydro …
Matched Iupac: … -1-yl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]-1H-1,2,4-triazole-3,5-diamine ... 1-{3,4-diazatricyclo[9.4.0.0^{2,7}]pentadeca-1(15),2(7),3,5,11,13-hexaen-5-yl}-N3-[(7S)-7-(pyrrolidin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … -1-yl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]-1H-1,2,4-triazole-3,5-diamine ... 1-{3,4-diazatricyclo[9.4.0.0^{2,7}]pentadeca-1(15),2(7),3,5,11,13-hexaen-5-yl}-N3-[(7S)-7-(pyrrolidin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
(2s,3s)-Trans-2,3-Dihydro-3-Hydroxyanthranilic Acid
Experimental
Matched Name: … (2s,3s)-Trans-2,3-Dihydro-3-Hydroxyanthranilic Acid …
Matched Iupac: … (5S,6S)-6-amino-5-hydroxycyclohexa-1,3-diene-1-carboxylic acid …
Matched Iupac: … (5S,6S)-6-amino-5-hydroxycyclohexa-1,3-diene-1-carboxylic acid …
Birabresib
Birabresib is under investigation in clinical trial NCT02698176 (A Dose Exploration Study With MK-8628 in Participants With Selected Advanced Solid Tumors (MK-8628-006)).
Investigational
Matched Synonyms: … 2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thienol[3,2,-f]-[1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl ... ]-N-(4-hydroxyphenyl)-acetamide …
Matched Iupac: … 2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0^{2,6}]trideca-2 ... (6),4,7,10,12-pentaen-9-yl]-N-(4-hydroxyphenyl)acetamide …
Matched Iupac: … 2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0^{2,6}]trideca-2 ... (6),4,7,10,12-pentaen-9-yl]-N-(4-hydroxyphenyl)acetamide …
4-oxo-4,5-dihydro-1,2,5-thiadiazole-3-carboxylic acid
Experimental
Matched Name: … 4-oxo-4,5-dihydro-1,2,5-thiadiazole-3-carboxylic acid …
Matched Iupac: … 4-hydroxy-1,2,5-thiadiazole-3-carboxylic acid …
Matched Iupac: … 4-hydroxy-1,2,5-thiadiazole-3-carboxylic acid …
(4S)-5-Fluoro-4-hydroxy-3,4-dihydro-2(1H)-pyrimidinone
Experimental
Matched Synonyms: … (4S)-5-Fluoro-4-hydroxy-3,4-dihydropyrimidin-2(1H)-one …
Matched Name: … (4S)-5-Fluoro-4-hydroxy-3,4-dihydro-2(1H)-pyrimidinone …
Matched Iupac: … (4S)-5-fluoro-4-hydroxy-1,2,3,4-tetrahydropyrimidin-2-one …
Matched Name: … (4S)-5-Fluoro-4-hydroxy-3,4-dihydro-2(1H)-pyrimidinone …
Matched Iupac: … (4S)-5-fluoro-4-hydroxy-1,2,3,4-tetrahydropyrimidin-2-one …
AZD-5153
Investigational
Matched Synonyms: … 2-piperazinone, 4-(2-(4-(1-(3-methoxy-1,2,4-triazolo(4,3-b)pyridazin-6-yl)-4-piperidinyl)phenoxy)ethyl …
Matched Iupac: … (3R)-4-{2-[4-(1-{3-methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperidin-4-yl)phenoxy]ethyl}-1,3-dimethylpiperazin ... -2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … (3R)-4-{2-[4-(1-{3-methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperidin-4-yl)phenoxy]ethyl}-1,3-dimethylpiperazin ... -2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Linafexor
Investigational
Matched Synonyms: … -8-yl)-2-fluorophenyl)-1,2,4-oxadiazol-5(4H)-one ... 1,2,4-OXADIAZOL-5(2H)-ONE, 3-(4-(3-((5-CYCLOPROPYL-3-(2,6-DICHLOROPHENYL)-4-ISOXAZOLYL)METHOXY)-8-AZABICYCLO ... (3.2.1)OCT-8-YL)-2-FLUOROPHENYL)- …
Matched Iupac: … ]octan-8-yl]-2-fluorophenyl}-4,5-dihydro-1,2,4-oxadiazol-5-one ... 3-{4-[(1R,3R,5S)-3-{[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}-8-azabicyclo[3.2.1 …
Matched Iupac: … ]octan-8-yl]-2-fluorophenyl}-4,5-dihydro-1,2,4-oxadiazol-5-one ... 3-{4-[(1R,3R,5S)-3-{[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}-8-azabicyclo[3.2.1 …
Denifanstat
Denifanstat is an orally bioavailable fatty acid synthase (FASN) inhibitor. Due to its antineoplastic activities, it is being investigated for various cancers.
Investigational
Matched Synonyms: … Benzonitrile, 4-(1-(4-cyclobutyl-2-methyl-5-(3-methyl-1h-1,2,4-triazol-5-yl)benzoyl)-4-piperidinyl)- …
Matched Iupac: … 4-{1-[4-cyclobutyl-2-methyl-5-(5-methyl-1H-1,2,4-triazol-3-yl)benzoyl]piperidin-4-yl}benzonitrile …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 4-{1-[4-cyclobutyl-2-methyl-5-(5-methyl-1H-1,2,4-triazol-3-yl)benzoyl]piperidin-4-yl}benzonitrile …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
(6-METHYL-3,4-DIHYDRO-2H-CHROMEN-2-YL)METHYLPHOSPHINATE
Experimental
Matched Name: … (6-METHYL-3,4-DIHYDRO-2H-CHROMEN-2-YL)METHYLPHOSPHINATE …
Matched Iupac: … {[(2S)-6-methyl-3,4-dihydro-2H-1-benzopyran-2-yl]methyl}phosphinate …
Matched Iupac: … {[(2S)-6-methyl-3,4-dihydro-2H-1-benzopyran-2-yl]methyl}phosphinate …
3-Pyridin-4-Yl-2,4-Dihydro-Indeno[1,2-.C.]Pyrazole
Experimental
Matched Name: … 3-Pyridin-4-Yl-2,4-Dihydro-Indeno[1,2-.C.]Pyrazole …
Matched Iupac: … 4-{2H,4H-indeno[1,2-c]pyrazol-3-yl}pyridine …
Matched Iupac: … 4-{2H,4H-indeno[1,2-c]pyrazol-3-yl}pyridine …
3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.] PYRAZOLE
Experimental
Matched Name: … 3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.] PYRAZOLE …
Matched Iupac: … (2S)-1-(4-bromophenyl)-3-{[5-(3-methyl-1H-indazol-5-yl)pyridin-3-yl]oxy}propan-2-amine …
Matched Iupac: … (2S)-1-(4-bromophenyl)-3-{[5-(3-methyl-1H-indazol-5-yl)pyridin-3-yl]oxy}propan-2-amine …
Selonsertib
Selonsertib is under investigation in clinical trial NCT03053050 (Safety and Efficacy of Selonsertib in Adults With Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis).
Investigational
Matched Synonyms: … BENZAMIDE, 5-(4-CYCLOPROPYL-1H-IMIDAZOL-1-YL)-2-FLUORO-4-METHYL-N-(6-(4-(1-METHYLETHYL)-4H-1,2,4-TRIAZOL ... 5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-{6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin ... 5-(4-Cyclopropyl-1H-imidazol-l-yl)-2-fluoro-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-4-methylbenzamide …
Matched Iupac: … 5-(4-cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-{6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin ... -2-yl}benzamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 5-(4-cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-{6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin ... -2-yl}benzamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
(7R)-7-(6,7-Dihydro-5H-cyclopenta[d]imidazo[2,1-b][1,3]thiazol-2-yl)-2,7-dihydro-1,4-thiazepine-3,6-dicarboxylic acid
Experimental
Matched Name: … (7R)-7-(6,7-Dihydro-5H-cyclopenta[d]imidazo[2,1-b][1,3]thiazol-2-yl)-2,7-dihydro-1,4-thiazepine-3,6-dicarboxylic …
Matched Iupac: … (7R)-7-{7-thia-1,9-diazatricyclo[6.3.0.0^{2,6}]undeca-2(6),8,10-trien-10-yl}-2,7-dihydro-1,4-thiazepine …
Matched Iupac: … (7R)-7-{7-thia-1,9-diazatricyclo[6.3.0.0^{2,6}]undeca-2(6),8,10-trien-10-yl}-2,7-dihydro-1,4-thiazepine …
OSI-027
OSI-027 has been used in trials studying the treatment of Any Solid Tumor or Lymphoma.
Investigational
Matched Synonyms: … CYCLOHEXANECARBOXYLIC ACID, 4-(4-AMINO-5-(7-METHOXY-1H-INDOL-2-YL)IMIDAZO(5,1-F)(1,2,4)TRIAZIN-7-YL)- …
Matched Iupac: … (1r,4r)-4-[4-amino-5-(7-methoxy-1H-indol-2-yl)imidazo[4,3-f][1,2,4]triazin-7-yl]cyclohexane-1-carboxylic …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … (1r,4r)-4-[4-amino-5-(7-methoxy-1H-indol-2-yl)imidazo[4,3-f][1,2,4]triazin-7-yl]cyclohexane-1-carboxylic …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Pociredir
Investigational
Matched Synonyms: … -4-(2-methyl-3-pyridinyl)-, (7as)- ... 7h-furo(4,3,2-gh)(1,2,4)triazolo(4',3':1,6)pyrido(2,3-c)(5,2)benzoxazonine, 12-fluoro-7a,8,13,14-tetrahydro …
Matched Iupac: … }.0^{18,22}]docosa-1(22),4(12),6,8,10,18,20-heptaene ... (15S)-21-fluoro-10-(2-methylpyridin-3-yl)-13,17-dioxa-3,5,7,8-tetraazapentacyclo[13.6.1.0^{4,12}.0^{5,9 …
Matched Iupac: … }.0^{18,22}]docosa-1(22),4(12),6,8,10,18,20-heptaene ... (15S)-21-fluoro-10-(2-methylpyridin-3-yl)-13,17-dioxa-3,5,7,8-tetraazapentacyclo[13.6.1.0^{4,12}.0^{5,9 …
Displaying drugs 2101 - 2125 of 8940 in total