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Displaying drugs 2151 - 2175 of 6759 in total
Perospirone
Perospirone is an atypical or second-generation antipsychotic of the azapirone family that antagonizes serotonin 5HT2A receptors and dopamine D2 receptors. It also displays affinity towards 5HT1A receptors as a partial agonist. Dainippon Sumitomo Pharma developed perospirone in Japan in 2001 for the treatment of acute schizophrenia and bipolar mania as...
Experimental
Matched Synonyms: … cis-N-(4-(4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl)butyl)-1,2-cyclohexanedicarboximide …
Matched Iupac: … (3aR,7aS)-2-{4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl}-octahydro-1H-isoindole-1,3-dione …
Matched Iupac: … (3aR,7aS)-2-{4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl}-octahydro-1H-isoindole-1,3-dione …
Resveratrol
Resveratrol (3,5,4'-trihydroxystilbene) is a polyphenolic phytoalexin. It is a stilbenoid, a derivate of stilbene, and is produced in plants with the help of the enzyme stilbene synthase. It exists as cis-(Z) and trans-(E) isomers. The trans- form can undergo isomerisation to the cis- form when heated or exposed to ultraviolet...
Investigational
Matched Synonyms: … (E)-5-(2-(4-hydroxyphenyl)ethenyl)-1,3-benzenediol(E)-5-(2-(4-hydroxyphenyl)ethenyl)-1,3-benzenediol ... 5-[(E)-2-(4-hydroxyphenyl)vinyl]benzene-1,3-diol ... 5-[(1E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol …
Matched Iupac: … 5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol …
Matched Iupac: … 5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol …
Canoctakin
Investigational
Brevenal
Investigational
CB-5083
Investigational
Matched Synonyms: … 1-(4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl)-2-methyl-1H-indole-4-carboxamide ... 1-(7,8-Dihydro-4-((phenylmethyl)amino)-5H-pyrano(4,3-d)pyrimidin-2-yl)-2-methyl-1H-indole-4-carboxamide …
Matched Iupac: … 1-[4-(benzylamino)-5H,7H,8H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indole-4-carboxamide …
Matched Iupac: … 1-[4-(benzylamino)-5H,7H,8H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indole-4-carboxamide …
MAX-40279
MAX-40279 is under investigation in clinical trial NCT03412292 (MAX-40279 in Subjects With Acute Myelogenous Leukemia (AML)).
Investigational
Matched Synonyms: … 7-(4-Fluoro-2-methoxyphenyl)-6-methyl-N-(1-(piperidin-4-yl)-1H-pyrazol-4-yl) thieno (3,2-d)pyrimidin- …
Matched Iupac: … N-[7-(4-fluoro-2-methoxyphenyl)-6-methylthieno[3,2-d]pyrimidin-2-yl]-1-(piperidin-4-yl)-1H-pyrazol-4- …
Matched Iupac: … N-[7-(4-fluoro-2-methoxyphenyl)-6-methylthieno[3,2-d]pyrimidin-2-yl]-1-(piperidin-4-yl)-1H-pyrazol-4- …
(4s)-5-Fluoro-L-Leucine
Experimental
Matched Name: … (4s)-5-Fluoro-L-Leucine …
Matched Iupac: … (2S,4S)-2-amino-5-fluoro-4-methylpentanoic acid …
Matched Iupac: … (2S,4S)-2-amino-5-fluoro-4-methylpentanoic acid …
Varoglutamstat
Investigational
Matched Synonyms: … (5s)-1-(1h-benzimidazol-5-yl)-5-(4- propoxyphenyl)imidazolidin-2-one ... (s)-1-(1h-benzimidazol-5-yl)-5-(4-propoxyphenyl)imidazolidin-2-one ... 2-imidazolidinone, 1-(1h-benzimidazol-6-yl)-5-(4-propoxyphenyl)-, (5s)- …
GDC-0134
Investigational
Matched Synonyms: … )hept-5-yl-4-pyrimidinyl)- ... 2-pyridinamine, 3-(difluoromethoxy)-5-(2-(3,3-difluoro-1-pyrrolidinyl)-6-(1s,4s)-2-oxa-5-azabicyclo(2.2.1 …
Matched Iupac: … ]pyrimidin-4-yl]pyridin-2-amine ... 3-(difluoromethoxy)-5-[2-(3,3-difluoropyrrolidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl …
Matched Iupac: … ]pyrimidin-4-yl]pyridin-2-amine ... 3-(difluoromethoxy)-5-[2-(3,3-difluoropyrrolidin-1-yl)-6-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl …
anti-OX40 antibody BMS 986178
A macrocyclic peptide (BMS-986189) with activity in binding and functional assays comparable to a PD-L1 antibody.
Investigational
A-98881
Experimental
Matched Iupac: … (5R,6R)-1,5-dibenzyl-6-hydroxy-2,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-1,2,4-triazepan-3-one …
NCX 950
NCX 950, beta2-adrenoceptor agonists is widely used in the treatment of pulmonary diseases.
Investigational
GS-9256
GS-9256 has been used in trials studying the treatment of HCV Infection and Chronic Hepatitis C Infection.
Investigational
Matched Iupac: … [(1S,4S,6R,14S,18R)-18-[(8-chloro-7-methoxy-2-{2-[(propan-2-yl)amino]-1,3-thiazol-4-yl}quinolin-4-yl) ... oxy]-14-{[(cyclopentyloxy)carbonyl]amino}-2,15-dioxo-3,16-diazatricyclo[14.3.0.0^{4,6}]nonadecan-4-yl …
BLZ-945
Investigational
Matched Iupac: … 4-[(2-{[(1R,2R)-2-hydroxycyclohexyl]amino}-1,3-benzothiazol-6-yl)oxy]-N-methylpyridine-2-carboxamide …
AMG-900
Investigational
Matched Synonyms: … 1-phthalazinamine, n-(4-((3-(2-amino-4-pyrimidinyl)-2-pyridinyl)oxy)phenyl)-4-(4-methyl-2-thienyl)- …
Matched Iupac: … N-(4-{[3-(2-aminopyrimidin-4-yl)pyridin-2-yl]oxy}phenyl)-4-(4-methylthiophen-2-yl)phthalazin-1-amine …
Matched Iupac: … N-(4-{[3-(2-aminopyrimidin-4-yl)pyridin-2-yl]oxy}phenyl)-4-(4-methylthiophen-2-yl)phthalazin-1-amine …
HER-902
Investigational
Neovastat
Neovastat is a naturally occurring anti-angiogenic compound, extracted from cartilage, with multiple anti-angiogenic mechanisms of action that provide broad therapeutic potential for a number of diseases. It is currently in international Phase III trials for renal cell carcinoma and non-small-cell lung cancer.
Investigational
MG-S-2525
Investigational
Matched Synonyms: … 5-(3,5-Dimethyl-4-hydroxybenzylamino)-3-(4-morpholin-4-yl-phenylamino)-1H-pyrazole-4-carboxylic acid …
Matched Iupac: … 5-{[(4-hydroxy-3,5-dimethylphenyl)methyl]amino}-3-{[4-(morpholin-4-yl)phenyl]amino}-1H-pyrazole-4-carboxamide …
Matched Iupac: … 5-{[(4-hydroxy-3,5-dimethylphenyl)methyl]amino}-3-{[4-(morpholin-4-yl)phenyl]amino}-1H-pyrazole-4-carboxamide …
EGT-101
EGT-101 is an adeno-associated viral vector serotype 9 (AAV9) vector-based gene therapy consisting of the human sulfamidase (SGSH) transgene. Developed by Esteve Pharmaceuticals, it is being investigated for Sanfilippo syndrome type A.
Investigational
Matched Description: … EGT-101 is an adeno-associated viral vector serotype 9 (AAV9) vector-based gene therapy consisting of …
Tagatose
Tagatose is a functional sweetener. It is a naturally occurring monosaccharide, specifically a hexose. It is commonly found in dairy with a similar texture and sweetened capacity to sucrose but with only a third of the calories. It is approved as a food additive as a low calorie sweetener. Additionally,...
Investigational
CRA-9334
Experimental
Matched Iupac: … 2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzodiazol-2-yl}-6-bromo-4-methylbenzen-1-olate …
Sri-9662
Experimental
Matched Iupac: … 6-[(1Z)-2-(2,5-dimethoxyphenyl)ethenyl]-5-methylpyrido[2,3-d]pyrimidine-2,4-diamine …
AZD-9684
AZD-9684 is the first member of a new anti-thrombotic class (CPU inhibitors). It is being developed by AstraZeneca.
Investigational
AZD-9164
AZD9164 has been used in trials studying the basic science and treatment of Chronic Obstructive Pulmonary Disease.
Investigational
Matched Iupac: … (3R)-1-[2-(4-fluorophenyl)ethyl]-3-{[(2S)-2-phenyl-2-(piperidin-1-yl)propanoyl]oxy}-1-azabicyclo[2.2.2 …
Displaying drugs 2151 - 2175 of 6759 in total