Displaying drugs 2176 - 2200 of 2744 in total
Epratuzumab
Epratuzumab is a humanized monoclonal antibody derived from the murine IG2a monoclonal antibody, LL2 (EPB-2). This agent may subsequently be well matched for use in oncology and the treatment of inflammatory autoimmune disorders, such as lupus.
Investigational
Modified vaccinia virus Ankara-85A antigen
Modified vaccinia virus Ankara-85A antigen is under investigation in clinical trial NCT00953927 (A Study of MVA85A in Healthy Infants).
Investigational
Matched Categories: … Recombinant Proteins …
V591
The V591 vaccine, part of Merck’s COVID-19 vaccine programming, was developed using a modified measles vaccine virus as a vector for COVID-19 antigen delivery . Through Merck’s acquisition of Thermis in May 2020, they were able to leverage Thermis’ platform knowledge and accelerate the development of V591 to phase I...
Investigational
Matched Description: … vaccine virus as a vector for COVID-19 antigen delivery[L30593]. ... The V591 vaccine, part of Merck’s COVID-19 vaccine programming, was developed using a modified measles …
Ensifentrine
Ensifentrine is under investigation in clinical trial NCT04535986 (A Phase 3 Clinical Trial to Evaluate the Safety and Efficacy of Ensifentrine in Patients With COPD).
Investigational
ISS-1018
ISS 1018 is a short, synthetic, unmethylated CpG oligodeoxynucleotide (CpG ODN) with immunostimulatory activity. ISS 1018 signals through Toll-like receptor 9 (TLR9) to induce the production of immunoglobulin by B cells and interferon (IFN) -alpha, IFN-beta, interleukin-12 (IL-12), and tumor necrosis factor - alpha (TNF-alpha) by plasmacytoid dendritic cells (pDC)....
Investigational
Matched Description: … (TLR9) to induce the production of immunoglobulin by B cells and interferon (IFN) -alpha, IFN-beta, interleukin …
Lactobacillus brevis
Investigational
TRC093
TRC093 is a recombinant humanized IgG1k monoclonal antibody.
Investigational
Matched Description: … TRC093 is a recombinant humanized IgG1k monoclonal antibody. …
Lusacomfar Alfa
Lusacomfar Alfa is a recombinant complement factor H
Investigational
Matched Description: … Lusacomfar Alfa is a recombinant complement factor H …
Rivanicline
Rivanicline (TC-2403, RJR-2403, (E)-metanicotine) is a partial agonist at neuronal nicotinic acetylcholine receptors, binding primarily to the α4β2 subtype. It was originally developed as a potential treatment for Alzheimer's disease for its nootropic effects but has also been found to inhibit the production of Interleukin-8. It has subsequently been developed...
Investigational
Matched Description: … Alzheimer's disease for its nootropic effects but has also been found to inhibit the production of Interleukin …
Terevalefim
Terevalefim is under investigation in clinical trial NCT02474667 (Reduce the Severity of DGF in Recipients of a Deceased Donor Kidney).
Investigational
Pomotrelvir
Pomotrelvir is under investigation in clinical trial NCT05543707 (PBI-0451 (Pomotrelvir) Phase 2 Study in Nonhospitalized Symptomatic Adults With COVID-19).
Investigational
Matched Description: … NCT05543707 (PBI-0451 (Pomotrelvir) Phase 2 Study in Nonhospitalized Symptomatic Adults With COVID-19 …
M-701
M-701 is a recombinant anti-EpCAM/CD3 bispecific antibody.
Investigational
Matched Description: … M-701 is a recombinant anti-EpCAM/CD3 bispecific antibody. …
Pemivibart
Pemivibart (Pemgarda) is a half life-extended monoclonal antibody targeting the SARS-CoV-2 spike protein receptor binding domain. It received emergency use authorization (EUA) by the FDA in March 2024 for pre-exposure prophylaxis (PrEP) of COVID-19 in certain high-risk patient populations.
Investigational
Matched Description: … emergency use authorization (EUA) by the FDA in March 2024 for pre-exposure prophylaxis (PrEP) of COVID-19 …
Leridistim
Leridistim is under investigation in clinical trial NCT00004215 (Leridistim Compared With Filgrastim in Treating Older Patients With Acute Myeloid Leukemia).
Investigational
Matched Categories: … Recombinant Proteins …
mRNA-1345
mRNA-1345 is an investigational RSV vaccine.
Investigational
Matched Categories: … Recombinant Proteins …
Azoximer bromide
Azoximer bromide is under investigation in clinical trial NCT04381377 (Efficacy and Safety of Polyoxidonium® in Hospitalized Patients With Coronavirus Disease COVID-19).
Investigational
Matched Description: … NCT04381377 (Efficacy and Safety of Polyoxidonium® in Hospitalized Patients With Coronavirus Disease COVID-19 …
Opaganib
Opaganib, also known as ABC294640, is a selective sphingosine kinase-2 (SK2) (https://go.drugbank.com/polypeptides/Q9NRA0) inhibitor that is orally administered. This drug has potential anticancer, anti-inflammatory, and antiviral activities, with potential applications in oncology, inflammation, the gastrointestinal system, and COVID-19.
Investigational
Matched Description: … activities, with potential applications in oncology, inflammation, the gastrointestinal system, and COVID-19 …
Mavelertinib
Mavelertinib is under investigation in clinical trial NCT02349633 (Study for Patients With NSCLC EGFR Mutations (Del 19 or L858R +/- T790M)).
Investigational
Matched Description: … under investigation in clinical trial NCT02349633 (Study for Patients With NSCLC EGFR Mutations (Del 19 …
V-SARS
COVID-19 convalescent plasma is currently being acquired from recovered COVID-19 patients and used as prophylaxis for the virus. This therapeutic concept was applied to the development of V-SARS, which heat inactivates the plasma, and packages it into a once-daily pill form. Immunitor Inc., the sponsor, is currently testing this oral...
Investigational
Matched Description: … [COVID-19 convalescent plasma] is currently being acquired from recovered COVID-19 patients and used …
CoVac-1
Sponsored by the University Hospital Tuebingen in Germany, CoVac-1 is a multi-peptide COVID-19 vaccine candidate created from HLA class I and HLA-DR T-cell epitopes of the S-protein . It is being investigated in the clinical trial NCT04546841 (Safety and Immunogenicity Trial of Multi-peptide Vaccination to Prevent COVID-19 Infection in Adults...
Investigational
Matched Description: … Sponsored by the University Hospital Tuebingen in Germany, CoVac-1 is a multi-peptide COVID-19 vaccine ... clinical trial NCT04546841 (Safety and Immunogenicity Trial of Multi-peptide Vaccination to Prevent COVID-19 …
Oleic monoethanolamide
Investigational
Matched Categories: … Experimental Unapproved Treatments for COVID-19 …
RO7200220
RO7200220 is a recombinant fully humanized anti-IL 6 monoclonal antibody.
Investigational
Matched Description: … RO7200220 is a recombinant fully humanized anti-IL 6 monoclonal antibody. …
M1-c6v1
M1-c6v1 is a recombinant oncolytic virus.
Investigational
Matched Description: … M1-c6v1 is a recombinant oncolytic virus. …
Displaying drugs 2176 - 2200 of 2744 in total