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Displaying drugs 2451 - 2475 of 2962 in total
Experimental
Matched Synonyms: … Cysteinyl-S-sulfonic acid
Matched Iupac: … (2R)-2-amino-3-(sulfosulfanyl)propanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Sulfur …
Moxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild to moderate essential hypertension. It is suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and calcium channel blockers are not appropriate or irresponsive. As well, moxonidine has been shown...
Approved
Investigational
Matched Synonyms: … [[(1,2,3,4-tetrahydro-3-methyl-8- quinolinyl)sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic acid
Matched Description: … suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and ... calcium channel blockers are not appropriate or irresponsive. …
Matched Categories: … moxonidine and diuretics …
Investigational
Matched Synonyms: … BQ-788 free acid, di(methyl-d)- …
Matched Iupac: … -carbonyl]amino}-4,4-dimethylpentanamido]-3-[1-(methoxycarbonyl)-1H-indol-3-yl]propanamido]hexanoic acid
EA-230 is under investigation in clinical trial NCT03145220 (Immunomodulation of EA-230 Following On-pump Coronary Artery Bypass Grafting (CABG)).
Investigational
Matched Synonyms: … (2S)-5-AMINO-2-(((2S)-2-AMINOPROPANOYL)AMINO)-5-OXO-PENTANOYL)AMINO)ACETYL)AMINO)-3-METHYL-BUTANOIC ACID
Matched Categories: … Amino Acids, Peptides, and Proteins …
Finafloxacin is a fluoroquinolone antibiotic indicated in the treatment of acute otitis externa (swimmer's ear) caused by the bacteria Pseudomonas aeruginosa and Staphylococcus aureus. Finafloxacin is marketed by Novartis under the brand Xtoro™, and was approved by the FDA in December 2014.
Approved
Investigational
Matched Synonyms: … fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b][1,4]oxazin-6(2H)-yl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid
Matched Iupac: … octahydropyrrolo[3,4-b]morpholin-6-yl]-8-cyano-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Matched Description: … the treatment of acute otitis externa (swimmer's ear) caused by the bacteria Pseudomonas aeruginosa and ... Finafloxacin is marketed by Novartis under the brand Xtoro™, and was approved by the FDA in December …
Investigational
Matched Synonyms: … 6S)-4,5-dihydroxy-2-(hydroxymethyl)-6-(((6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo
Matched Iupac: … 2-{[(2S,3R,4S,5R,6R)-2-{[(2R,3S,4R,5R,6S)-6-{[(6aR,10aR)-6,6,9-trimethyl-3-pentyl-6H,6aH,7H,8H,10aH-benzo
Matched Categories: … Cannabinoids and similars …
Pantoprazole is a first-generation proton pump inhibitor (PPI) used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison (ZE) Syndrome. It can also be...
Approved
Matched Description: … This effect leads to inhibition of both basal and stimulated gastric acid secretion, irrespective of ... gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and ... and bone fractures later in life. …
Matched Categories: … Alimentary Tract and Metabolism ... pantoprazole, amoxicillin and clarithromycin ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) ... pantoprazole, amoxicillin, clarithromycin and metronidazole ... Acid Reducers …
Matched Products: … PANTOPRAZOL ACIS 40MG ... PANTOPRAZOL ACIS 20MG …
Navtemadlin (AMG-232) is under investigation in clinical trial NCT03041688 (MDM2 Inhibitor AMG-232 and Decitabine in Treating Patients With Relapsed, Refractory, or Newly-Diagnosed Acute Myeloid Leukemia).
Investigational
Matched Synonyms: … chlorophenyl)-3-methyl-1-[ (2S)-3 -methyl-1-(propan-2- ylsulfonyl)butan-2-yl]-2-oxopiperidin-3-yl}acetic acid
Matched Iupac: … chlorophenyl)-3-methyl-1-[(2S)-3-methyl-1-(propane-2-sulfonyl)butan-2-yl]-2-oxopiperidin-3-yl]acetic acid
Matched Description: … Navtemadlin (AMG-232) is under investigation in clinical trial NCT03041688 (MDM2 Inhibitor AMG-232 and
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Amlitelimab is under investigation in clinical trial NCT06181435 (A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (COAST 2)).
Investigational
Matched Synonyms: … Immunoglobulin g4 (235-proline,242-glutamic acid), anti-(human ox40 ligand) (human monoclonal ky1005- …
Matched Description: … Amlitelimab is under investigation in clinical trial NCT06181435 (A Study to Evaluate the Efficacy and ... Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and
A synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Approved
Matched Synonyms: … Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid
Matched Iupac: … methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13),6,8,11-tetraene-11-carboxylic acid
Matched Categories: … ofloxacin and ornidazole ... Metabolic Side Effects of Drugs and Substances …
Ceftibuten is a third-generation cephalosporin antibiotic that is orally-administered. It is typically used to treat acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsilitis.
Approved
Investigational
Matched Synonyms: … -(2-amino-4-thiazolyl)-4-carboxycrotonamido)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
Matched Iupac: … amino-1,3-thiazol-4-yl)-4-carboxybut-2-enamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Description: … acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and
Refractory anaplastic astrocytoma (WHO grade III) and Glioblastoma multiforme (WHO grade IV) are primary malignant brain tumours with poor prognosis and limited treatment options. Despite considerable genetic heterogeneity, these tumours often have impaired DNA repair systems, rendering them initially sensitive to alkylating agents, although they invariably develop resistance to these...
Approved
Investigational
Matched Description: … Refractory anaplastic astrocytoma (WHO grade III) and Glioblastoma multiforme (WHO grade IV) are primary ... malignant brain tumours with poor prognosis and limited treatment options. ... guanine bases leading to DNA lesions and eventual apoptosis. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … MOZOLA® 20MG CAPSULA
Investigational
Matched Synonyms: … 2-Amino-4-[11C]methylsulfanyl-butanoic acid, l-[S methyl[11C]methionine …
Matched Iupac: … (2S)-2-amino-4-[(11C)methylsulfanyl]butanoic acid
Experimental
Matched Name: … 4-{2,4-Bis[(3-Nitrobenzoyl)Amino]Phenoxy}Phthalic Acid
Matched Iupac: … 4-[2,4-bis(3-nitrobenzamido)phenoxy]benzene-1,2-dicarboxylic acid
Experimental
Matched Name: … N-Pyridoxyl-7-Keto-8-Aminopelargonic Acid-5'-Monophosphate …
Matched Iupac: … (8S)-8-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-7-oxononanoic acid
Experimental
Matched Name: … 4-oxo-4,5-dihydro-1,2,5-thiadiazole-3-carboxylic acid
Matched Iupac: … 4-hydroxy-1,2,5-thiadiazole-3-carboxylic acid
Experimental
Matched Name: … 6-phenyl-4(R)-(7-phenyl-heptanoylamino)-hexanoic acid
Matched Iupac: … (4R)-6-phenyl-4-(7-phenylheptanamido)hexanoic acid
Experimental
Matched Name: … 3-(7-hydroxy-8-ribityllumazine-6-yl) propionic acid
Matched Iupac: … 3-{4,7-dihydroxy-2-oxo-8-[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]-2,8-dihydropteridin-6-yl}propanoic acid
Experimental
Matched Name: … 5-Carbamoyl-1,1':4',1''-terphenyl-3-carboxylic acid
Matched Iupac: … 3-{[1,1'-biphenyl]-4-yl}-5-carbamoylbenzoic acid
Experimental
Matched Name: … N-PYRIDOXYL-2-METHYL-L-GLUTAMIC ACID-5'-MONOPHOSPHATE …
Matched Iupac: … 2S)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-2-methylpentanedioic acid
Experimental
Matched Name: … 1-METHYL-3-PHENYL-1H-PYRAZOL-5-YLSULFAMIC ACID
Matched Iupac: … N-(1-methyl-3-phenyl-1H-pyrazol-5-yl)sulfamic acid
Experimental
Matched Name: … (2S)-2-{[HYDROXY(4-IODOBENZYL)PHOSPHORYL]METHYL}PENTANEDIOIC ACID
Matched Iupac: … (2S)-2-({hydroxy[(4-iodophenyl)methyl]phosphoryl}methyl)pentanedioic acid
Experimental
Matched Name: … 4-BROMO-3-(CARBOXYMETHOXY)-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID
Matched Iupac: … 4-bromo-3-(carboxymethoxy)-5-phenylthiophene-2-carboxylic acid
Experimental
Matched Name: … 3-(CARBOXYMETHOXY)THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID
Matched Iupac: … 3-(carboxymethoxy)thieno[2,3-b]pyridine-2-carboxylic acid
Experimental
Matched Name: … (1R)-4-(3-phenoxyphenyl)-1-phosphonobutane-1-sulfonic acid
Matched Iupac: … (1R)-4-(3-phenoxyphenyl)-1-phosphonobutane-1-sulfonic acid
Displaying drugs 2451 - 2475 of 2962 in total