Small ribosomal subunit protein uS4

BE0000019ProteinEscherichia coli (strain K12)rpsD

One of two assembly initiator proteins for the 30S subunit, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. It is acted on by 5 drugs in DrugBank.

Gene name
rpsD
UniProtKB entry
P0A7V8Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
206 residues · 23,469 Da
Also known as
30S ribosomal protein S4 · ramA

Resolves to

Protein
UniProtP0A7V8UniProt nameRS4_ECOLI
Gene
NCBI Gene947793GenBank42798
Pharmacology
KEGGecj:JW3258
Structure
PDB1EG0PDB1M5GPDB2YKR
Drugs

What you can answer from here — as of May 03, 2025

5DrugsApproved to experimental, with action, bond type and pharmacological action
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12GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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29+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Small ribosomal subunit protein uS4, how selective are they, and which programs against it are still in active trials?

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