Annexin A1

BE0000422ProteinHumansANXA1

Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. It is acted on by 19 drugs in DrugBank.

Gene name
ANXA1
UniProtKB entry
P04083Swiss-Prot
Cellular location
Nucleus
Residues / weight
346 residues · 38,714 Da
Also known as
Annexin I · Annexin-1 · ANX1 · Calpactin II · Calpactin-2

Resolves to

Protein
UniProtP04083UniProt nameANXA1_HUMAN
Gene
HGNCHGNC:533NCBI Gene301GenBank12654863GeneCardsANXA1
Pharmacology
KEGGhsa:301
Structure
PDB1AINPDB1BO9PDB1QLS
Drugs

What you can answer from here — as of September 07, 2019

19DrugsApproved to experimental, with action, bond type and pharmacological action
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18GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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64+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Annexin A1, how selective are they, and which programs against it are still in active trials?

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