5-hydroxytryptamine receptor 1F

BE0000460ProteinHumansHTR1F

G protein-coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:21422162, PubMed:34239069, PubMed:8380639, PubMed:8384716). It is acted on by 12 drugs in DrugBank.

Gene name
HTR1F
UniProtKB entry
P30939Swiss-Prot
Cellular location
Cell membrane
Residues / weight
366 residues · 41,709 Da
Also known as
5-HT-1F · 5-HT1F · HTR1EL · Serotonin receptor 1F

Resolves to

Protein
UniProtP30939UniProt name5HT1F_HUMAN
Gene
HGNCHGNC:5292NCBI Gene3355GenBank307420GeneCardsHTR1F
Pharmacology
IUPHAR/GtoPdb5KEGGhsa:3355
Structure
PDB21AGPDB21AHPDB7EXD
Drugs

What you can answer from here — as of September 07, 2019

12DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
2GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
56+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on 5-hydroxytryptamine receptor 1F, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In