Maltase-glucoamylase

BE0000837ProteinHumansMGAM

Alpha-(1,4) exo-glucosidase involved in breakdown of dietary starch oligosaccharides in small intestine. It is acted on by 21 drugs in DrugBank.

Gene name
MGAM
UniProtKB entry
O43451Swiss-Prot
Cellular location
Apical cell membrane
Residues / weight
2,753 residues · 312,020 Da
Also known as
Alpha-1,4-glucosidase · MGA · MGAML

Resolves to

Protein
UniProtO43451UniProt nameMGA_HUMAN
Gene
HGNCHGNC:7043NCBI Gene8972GenBank17648144GeneCardsMGAM
Pharmacology
IUPHAR/GtoPdb2627KEGGhsa:8972
Structure
PDB2QLYPDB2QMJPDB3CTT
Drugs

What you can answer from here — as of September 03, 2024

21DrugsApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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54+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Maltase-glucoamylase, how selective are they, and which programs against it are still in active trials?

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