Signal transducer and activator of transcription 5B

BE0000891ProteinHumansSTAT5B

Signal transducer and transcription activator that mediates cellular responses to cytokines, hormones and growth factors (PubMed:29844444, PubMed:9188471). It is acted on by 1 drug in DrugBank.

Gene name
STAT5B
UniProtKB entry
P51692Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
787 residues · 89,865 Da

Resolves to

Protein
UniProtP51692UniProt nameSTA5B_HUMAN
Gene
HGNCHGNC:11367NCBI Gene6777GenBank6981726GeneCardsSTAT5B
Pharmacology
KEGGhsa:6777
Structure
PDB6MBWPDB6MBZ
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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12GO termsFunction, process and component, as structured annotations
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5Pfam domainsDomain architecture mapped to Pfam families and clans
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26+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Signal transducer and activator of transcription 5B, how selective are they, and which programs against it are still in active trials?

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