Collagenase 3

BE0000966ProteinHumansMMP13

Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. It is acted on by 22 drugs in DrugBank.

Gene name
MMP13
UniProtKB entry
P45452Swiss-Prot
Cellular location
Secreted, extracellular space, extracellular matrix
Residues / weight
471 residues · 53,819 Da
Also known as
3.4.24.- · Matrix metalloproteinase-13 · MMP-13

Resolves to

Protein
UniProtP45452UniProt nameMMP13_HUMAN
Gene
HGNCHGNC:7159NCBI Gene4322GenBank516386GeneCardsMMP13
Pharmacology
IUPHAR/GtoPdb1637KEGGhsa:4322
Structure
PDB1EUBPDB1FLSPDB1FM1
Drugs

What you can answer from here — as of September 07, 2019

22DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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89+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Collagenase 3, how selective are they, and which programs against it are still in active trials?

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