CTS-1027

DB08490InvestigationalSmall molecule

CTS-1027 has been used in trials studying the treatment of Hepatitis C and Chronic Hepatitis C Virus Infection.

Mechanism: Pharmacologically active on Collagenase 3, Neutrophil collagenase, and Macrophage metalloelastase
Curator reviewed
Formula / weight: C₁₉H₂₀ClNO₆S · 425.883 g/mol (avg)
Also known as: 2H-PYRAN-4-CARBOXAMIDE, 4-(((4-(4-CHLOROPHENOXY)PHENYL)SULFONYL)METHYL)TETRAHYDRO-N-HYDROXY- · 4-(((4-(4-CHLOROPHENOXY)PHENYL)SULFONYL)-METHYL) TETRAHYDRO-N-HYDROXY-2H-PYRAN-4-CARBOXAMIDE · 4-(4-(4-CHLORO-PHENOXY)-BENZENESULFONYLMETHYL )-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HYDROXYAMIDE · 4-(4-(4-CHLORO-PHENOXY)-BENZENESULFONYLMETHYL)-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HYDROXYAMIDE · 4-[[[4-(4-Chlorophenoxy)phenyl]sulfonyl]-methyl] tetrahydro-N-hydroxy-2H-pyran-4-carboxamide
Code names: CTS 1027 · RO-1130830 · RS-130830

Resolves to

Compound

Structure

InChIKeyROSNVSQTEGHUKU-UHFFFAOYSA-NSMILESONC(=O)C1(CS(=O)(=O)C2=CC=C(OC3=CC=C(Cl)C=C3)C=C2)CCOCC1

Targets

What you can answer from here — as of June 15, 2026

8Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

3Clinical trialsPhase, status and sponsor resolved per trial

35+ReferencesStructured and connected to the statements they support

Which drugs share a target with CTS-1027, and which of those have an active Phase 3 trial?

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