UDP-N-acetylmuramoylalanine--D-glutamate ligase

BE0001258ProteinEscherichia coli (strain K12)murD

Cell wall formation (Probable). It is acted on by 8 drugs in DrugBank.

Gene name
murD
UniProtKB entry
P14900Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
438 residues · 46,973 Da
Also known as
6.3.2.9 · D-glutamic acid-adding enzyme · UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase

Resolves to

Protein
UniProtP14900UniProt nameMURD_ECOLI
Gene
NCBI Gene944818GenBank42060
Pharmacology
KEGGecj:JW0086
Structure
PDB1E0DPDB1EEHPDB1UAG
Drugs

What you can answer from here — as of September 07, 2019

8DrugsApproved to experimental, with action, bond type and pharmacological action
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9GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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20+ReferencesStructured and connected to the statements they support
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Which compounds in development act on UDP-N-acetylmuramoylalanine--D-glutamate ligase, and which indications are they being tested in?

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