GDP-mannose mannosyl hydrolase

BE0001756ProteinEscherichia coli (strain K12)gmm

Hydrolyzes both GDP-mannose and GDP-glucose (PubMed:10913267, PubMed:23481913, PubMed:7592609). It is acted on by 1 drug in DrugBank.

Gene name
gmm
UniProtKB entry
P32056Swiss-Prot
Residues / weight
159 residues · 18,273 Da
Also known as
3.6.1.- · Colanic acid biosynthesis protein WcaH · GDPMH · nudD · wcaH

Resolves to

Protein
UniProtP32056UniProt nameGMM_ECOLI
Gene
NCBI Gene946559
Pharmacology
KEGGecj:JW5335
Structure
PDB1RYAPDB2GT2PDB2GT4
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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13+ReferencesStructured and connected to the statements they support
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Which compounds in development act on GDP-mannose mannosyl hydrolase, and which indications are they being tested in?

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