Isoaspartyl dipeptidase

BE0001801ProteinEscherichia coli (strain K12)iadA

Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. It is acted on by 2 drugs in DrugBank.

Gene name
iadA
UniProtKB entry
P39377Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
390 residues · 41,084 Da
Also known as
3.4.19.- · yjiF

Resolves to

Protein
UniProtP39377UniProt nameIADA_ECOLI
Gene
NCBI Gene948853GenBank640031
Pharmacology
KEGGecj:JW4291
Structure
PDB1ONWPDB1ONXPDB1PO9
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Isoaspartyl dipeptidase, and which indications are they being tested in?

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