Superoxide dismutase [Cu-Zn]

BE0002390ProteinHumansSOD1

Destroys radicals which are normally produced within the cells and which are toxic to biological systems (PubMed:18948262, PubMed:24140062). It is acted on by 30 drugs in DrugBank.

Gene name
SOD1
UniProtKB entry
P00441Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
154 residues · 15,936 Da
Also known as
1.15.1.1 · 1.8.-.- · hSod1 · Hydrogen sulfide oxidase · Superoxide dismutase 1

Resolves to

Protein
UniProtP00441UniProt nameSODC_HUMAN
Gene
HGNCHGNC:11179NCBI Gene6647GeneCardsSOD1
Pharmacology
KEGGhsa:6647
Structure
PDB1AZVPDB1BA9PDB1DSW
Drugs

What you can answer from here — as of September 07, 2019

30DrugsApproved to experimental, with action, bond type and pharmacological action
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7Clinical trialsTrials of drugs acting on it, by phase and status
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13GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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120+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Superoxide dismutase [Cu-Zn], how selective are they, and which programs against it are still in active trials?

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