U1 small nuclear ribonucleoprotein A

BE0002708ProteinHumansSNRPA

Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. It is acted on by 1 drug in DrugBank.

Gene name
SNRPA
UniProtKB entry
P09012Swiss-Prot
Cellular location
Nucleus
Residues / weight
282 residues · 31,279 Da
Also known as
U1 snRNP A · U1-A · U1A

Resolves to

Protein
UniProtP09012UniProt nameSNRPA_HUMAN
Gene
HGNCHGNC:11151NCBI Gene6626GeneCardsSNRPA
Pharmacology
KEGGhsa:6626
Structure
PDB1AUDPDB1DRZPDB1DZ5
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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20+ReferencesStructured and connected to the statements they support
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Which compounds in development act on U1 small nuclear ribonucleoprotein A, and which indications are they being tested in?

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