Sensor protein PhoQ

BE0003293ProteinEscherichia coli (strain K12)phoQ

Member of the two-component regulatory system PhoP/PhoQ involved in adaptation to low Mg(2+) environments and the control of acid resistance genes. It is acted on by 1 drug in DrugBank.

Gene name
phoQ
UniProtKB entry
P23837Swiss-Prot
Cellular location
Cell inner membrane
Residues / weight
486 residues · 55,299 Da
Also known as
2.7.13.3 · Sensor histidine protein kinase/phosphatase PhoQ

Resolves to

Protein
UniProtP23837UniProt namePHOQ_ECOLI
Gene
NCBI Gene946326
Pharmacology
KEGGecj:JW1115
Structure
PDB1ID0PDB3BQ8PDB3BQA
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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12GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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20+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Sensor protein PhoQ, and which indications are they being tested in?

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