Transient receptor potential cation channel subfamily V member 3

BE0003416ProteinHumansTRPV3

Non-selective calcium permeant cation channel (PubMed:12077604, PubMed:12077606, PubMed:26818531, PubMed:37648856, PubMed:38691614). It is acted on by 12 drugs in DrugBank.

Gene name
TRPV3
UniProtKB entry
Q8NET8Swiss-Prot
Cellular location
Cell membrane
Residues / weight
790 residues · 90,635 Da
Also known as
TrpV3 · Vanilloid receptor-like 3 · VRL-3

Resolves to

Protein
UniProtQ8NET8UniProt nameTRPV3_HUMAN
Gene
HGNCHGNC:18084NCBI Gene162514GeneCardsTRPV3
Pharmacology
IUPHAR/GtoPdb509KEGGhsa:162514
Structure
PDB6H9JPDB6HA6PDB6MHO
Drugs

What you can answer from here — as of September 07, 2019

12DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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23+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Transient receptor potential cation channel subfamily V member 3, how selective are they, and which programs against it are still in active trials?

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