Prostaglandin E2 receptor EP4 subtype

BE0003522ProteinHumansPTGER4

Receptor for prostaglandin E2 (PGE2). It is acted on by 13 drugs in DrugBank.

Gene name
PTGER4
UniProtKB entry
P35408Swiss-Prot
Cellular location
Cell membrane
Residues / weight
488 residues · 53,119 Da
Also known as
PGE receptor EP4 subtype · PGE2 receptor EP4 subtype · Prostanoid EP4 receptor · PTGER2

Resolves to

Protein
UniProtP35408UniProt namePE2R4_HUMAN
Gene
HGNCHGNC:9596NCBI Gene5734GeneCardsPTGER4
Pharmacology
IUPHAR/GtoPdb343KEGGhsa:5734
Structure
PDB5YHLPDB5YWYPDB7D7M
Drugs

What you can answer from here — as of September 07, 2019

13DrugsApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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45+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Prostaglandin E2 receptor EP4 subtype, how selective are they, and which programs against it are still in active trials?

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