Carbonic anhydrase 14

BE0003634ProteinHumansCA14

Reversible hydration of carbon dioxide. It is acted on by 20 drugs in DrugBank.

Gene name
CA14
UniProtKB entry
Q9ULX7Swiss-Prot
Cellular location
Membrane
Residues / weight
337 residues · 37,667 Da
Also known as
4.2.1.1 · CA-XIV · Carbonate dehydratase XIV · Carbonic anhydrase XIV

Resolves to

Protein
UniProtQ9ULX7UniProt nameCAH14_HUMAN
Gene
HGNCHGNC:1372NCBI Gene23632GenBank6009640GeneCardsCA14
Pharmacology
IUPHAR/GtoPdb2598KEGGhsa:23632
Structure
PDB4LU3PDB5CJF
Drugs

What you can answer from here — as of September 07, 2019

20DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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80+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Carbonic anhydrase 14, how selective are they, and which programs against it are still in active trials?

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