Solute carrier family 28 member 3

BE0003672ProteinHumansSLC28A3

Sodium-dependent, pyrimidine- and purine-selective (PubMed:11032837, PubMed:15861042, PubMed:16446384, PubMed:17140564, PubMed:21998139). It is acted on by 10 drugs in DrugBank.

Gene name
SLC28A3
UniProtKB entry
Q9HAS3Swiss-Prot
Cellular location
Cell membrane
Residues / weight
691 residues · 76,930 Da
Also known as
CNT 3 · CNT3 · Concentrative Na(+)-nucleoside cotransporter 3 · hCNT3

Resolves to

Protein
UniProtQ9HAS3UniProt nameS28A3_HUMAN
Gene
HGNCHGNC:16484NCBI Gene64078GenBank10732815GeneCardsSLC28A3
Pharmacology
IUPHAR/GtoPdb1116KEGGhsa:64078
Structure
PDB6KSW
Drugs

What you can answer from here — as of September 07, 2019

10DrugsApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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10GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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23+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Solute carrier family 28 member 3, how selective are they, and which programs against it are still in active trials?

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