Proteasome subunit alpha type-1

BE0003910ProteinHumansPSMA1

Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. It is acted on by 1 drug in DrugBank.

Gene name
PSMA1
UniProtKB entry
P25786Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
263 residues · 29,555 Da
Also known as
30 kDa prosomal protein · alpha-6 · HC2 · Macropain subunit C2 · Multicatalytic endopeptidase complex subunit C2

Resolves to

Protein
UniProtP25786UniProt namePSA1_HUMAN
Gene
HGNCHGNC:9530NCBI Gene5682GenBank220022GeneCardsPSMA1
Pharmacology
KEGGhsa:5682
Structure
PDB4R3OPDB4R67PDB5A0Q
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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30GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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15+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Proteasome subunit alpha type-1, and which indications are they being tested in?

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