3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase

BE0004016ProteinEscherichia coli (strain K12)fabA

Necessary for the introduction of cis unsaturation into fatty acids (PubMed:8910376). It is acted on by 1 drug in DrugBank.

Gene name
fabA
UniProtKB entry
P0A6Q3Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
172 residues · 18,969 Da
Also known as
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA · 4.2.1.59 · Beta-hydroxydecanoyl thioester dehydrase · Trans-2-decenoyl-[acyl-carrier-protein] isomerase

Resolves to

Protein
UniProtP0A6Q3UniProt nameFABA_ECOLI
Gene
NCBI Gene945568GenBank1256744
Pharmacology
KEGGecj:JW0937
Structure
PDB1MKAPDB1MKBPDB4KEH
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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12+ReferencesStructured and connected to the statements they support
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Which compounds in development act on 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, and which indications are they being tested in?

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