NT-3 growth factor receptor

BE0009501ProteinHumansNTRK3

Receptor tyrosine kinase involved in nervous system and probably heart development. It is acted on by 19 drugs in DrugBank.

Gene name
NTRK3
UniProtKB entry
Q16288Swiss-Prot
Cellular location
Membrane
Residues / weight
839 residues · 94,427 Da
Also known as
2.7.10.1 · GP145-TrkC · Neurotrophic tyrosine kinase receptor type 3 · Trk-C · TRKC

Resolves to

Protein
UniProtQ16288UniProt nameNTRK3_HUMAN
Gene
HGNCHGNC:8033NCBI Gene4916GeneCardsNTRK3
Pharmacology
IUPHAR/GtoPdb1819KEGGhsa:4916
Structure
PDB1WWCPDB3V5QPDB4YMJ
Drugs

What you can answer from here — as of September 07, 2019

19DrugsApproved to experimental, with action, bond type and pharmacological action
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3Clinical trialsTrials of drugs acting on it, by phase and status
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12GO termsFunction, process and component, as structured annotations
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6Pfam domainsDomain architecture mapped to Pfam families and clans
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48+ReferencesStructured and connected to the statements they support
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Which approved drugs act on NT-3 growth factor receptor, how selective are they, and which programs against it are still in active trials?

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