Amino Acids, Acidic

Amino Acids, Acidic
Accession Number

Amino acids with side chains that are negatively charged at physiological pH.

DrugDrug Description
Aspartic acidAn amino acid commonly found as a component in total parenteral nutrition.
Magnesium aspartateMagnesium aspartate is a magnesium salt of aspartic acid that is commonly used as a mineral supplement. It displays high oral bioavailability and water solubiltiy compared to other magnesium salts...
Potassium aspartateA potassium supplement used to treat hypokalemia or hyperammonemia.
Glutamic acidAn amino acid commonly found as a component in total parenteral nutrition.
PemetrexedA folate analog used to treat mesothelioma and non-small cell lung cancer.
KetamineA rapid-acting general anesthetic and NMDA receptor antagonist used for induction of anesthesia diagnostic and surgical procedures typically in combination with a muscle relaxant.
5'-S-methyl-5'-thioadenosineNot Available
Glutamine hydroxamateNot Available
D-Aspartic AcidThe D-isomer of aspartic acid. [PubChem]
Pidolic acidThere is currently no clinically approved and/or marketed medicine that relies upon pidolic acid as an active ingredient for any formal therapeutic indication. Although pidolic acid may be sold in...
2s,4r-4-MethylglutamateNot Available
Sparfosic acidSparfosic acid is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at the terminal nitrogen...
Beta-Hydroxyaspartic AcidNot Available
3-Methylglutamic acidNot Available
gamma-carboxy-L-glutamic acidNot Available
N-Carbamoylaspartic acidAn amino acid commonly found as a component in total parenteral nutrition.
Adenylosuccinic acidNot Available
Aspartate SemialdehydeNot Available
TrofinetideInvestigated for use/treatment in traumatic brain injuries.
Carglumic acidAn analog of N-acetylglutamate (NAG) used for the treatment of acute and chronic hyperammonemia in patients with N-acetylglutamate synthase (NAGS) deficiency.
Levomefolic acidA folate supplement used to prevent neural tube defects in pregnancy or folate deficiency.
PidotimodA synthetic agent with immunomodulatory properties used in patients with documented cell-mediated immunosuppression to stimulate their immunity during lung and urinary tract infections.
Oxothiazolidinecarboxylic acidProcysteine has been used in trials studying the treatment of HIV Infections.
TheanineTheanine, a precursor of ethylamine, is found in green tea. It is under investigation in clinical trial NCT00291070 (Effects of L-Theanine in Boys With ADHD).
Iofolastat I-123Iofolastat I-123 is under investigation in clinical trial NCT00992745 (A Phase I Pilot Study Comparing 123I MIP 1072 Versus 111In Capromab Pendetide in Subjects With Metastatic Prostate Cancer).
PCI-27483PCI-27483 has been used in trials studying the treatment of Pancreatic Cancer, Ductal Adrenocarcinoma, and Exocrine Pancreatic Cancer.
Paclitaxel poliglumexNot Annotated
Demplatin pegraglumerDemplatin pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and Gemcitabine Versus Gemcitabine Alone in Pancreatic Cancer).
Arginine aspartateAn ingredient in products indicated to treat exhaustion during stress, endurance sports, or in the elderly.
MetadoxineA medication used to increase the clearance of alcohol in patients with chronic alcohol dependancy.
Drugs & Drug Targets
Aspartic acidCalcium-binding mitochondrial carrier protein Aralar2target
Aspartic acidAspartate aminotransferase, cytoplasmictarget
Aspartic acidAspartoacylasetarget
Aspartic acidAsparagine synthetase [glutamine-hydrolyzing]target
Aspartic acidArgininosuccinate synthasetarget
Aspartic acidAminoacylase-1target
Aspartic acidAspartate aminotransferase, mitochondrialtarget
Aspartic acidAspartate--tRNA ligase, cytoplasmictarget
Aspartic acidCalcium-binding mitochondrial carrier protein Aralar1target
Aspartic acidAspartyl/asparaginyl beta-hydroxylasetarget
Aspartic acidMultifunctional protein ADE2target
Aspartic acidAdenylosuccinate synthetase isozyme 2target
Aspartic acidExcitatory amino acid transporter 3target
Aspartic acidArgininosuccinate synthetase, isoform CRA_atarget
Aspartic acidAspartate--tRNA ligase, mitochondrialtarget
Aspartic acidIsoaspartyl peptidase/L-asparaginasetarget
Aspartic acidRibonuclease pancreatictarget
Aspartic acidLysozyme Ctarget
Aspartic acidMonocarboxylate transporter 10transporter
Aspartic acidCAD proteinenzyme
Aspartic acidAdenylosuccinate Synthetasestarget
Glutamic acidGlutamate dehydrogenase 1, mitochondrialtarget
Glutamic acidGlutamate receptor ionotropic, kainate 1target
Glutamic acidGlutamate receptor 1target
Glutamic acidGlutamate--cysteine ligase regulatory subunittarget
Glutamic acidGlutamate carboxypeptidase 2target
Glutamic acidGlutamate decarboxylase 2target
Glutamic acidGlutamate decarboxylase 1target
Glutamic acidFormimidoyltransferase-cyclodeaminasetarget
Glutamic acidGlutamate receptor 2target
Glutamic acidGlutamate receptor 3target
Glutamic acidGlutamate receptor 4target
Glutamic acidDelta-1-pyrroline-5-carboxylate synthasetarget
Glutamic acidGlutamate receptor ionotropic, kainate 2target
Glutamic acidGlutamate receptor ionotropic, kainate 3target
Glutamic acidMetabotropic glutamate receptor 1target
Glutamic acidMetabotropic glutamate receptor 4target
Glutamic acidGlutamate receptor ionotropic, kainate 4target
Glutamic acidGlutamate receptor ionotropic, kainate 5target
Glutamic acidMetabotropic glutamate receptor 7target
Glutamic acidMetabotropic glutamate receptor 8target
Glutamic acidExcitatory amino acid transporter 5target
Glutamic acid5-oxoprolinasetarget
Glutamic acidPhosphoribosylformylglycinamidine synthasetarget
Glutamic acidBranched-chain-amino-acid aminotransferase, mitochondrialtarget
Glutamic acidGlutamate receptor ionotropic, NMDA 2Dtarget
Glutamic acidGlutaminase kidney isoform, mitochondrialtarget
Glutamic acidAspartate aminotransferase, mitochondrialtarget
Glutamic acidBifunctional glutamate/proline--tRNA ligasetarget
Glutamic acidAsparagine synthetase [glutamine-hydrolyzing]target
Glutamic acidGlutamine synthetasetarget
Glutamic acidAspartate aminotransferase, cytoplasmictarget
Glutamic acidTyrosine aminotransferasetarget
Glutamic acidAlanine aminotransferase 1target
Glutamic acidVitamin K-dependent gamma-carboxylasetarget
Glutamic acidExcitatory amino acid transporter 1target
Glutamic acidExcitatory amino acid transporter 2target
Glutamic acidExcitatory amino acid transporter 3target
Glutamic acidGlutamate--cysteine ligase catalytic subunittarget
Glutamic acidExcitatory amino acid transporter 4target
Glutamic acidGlutamate dehydrogenase 2, mitochondrialtarget
Glutamic acidGMP synthase [glutamine-hydrolyzing]target
Glutamic acidBranched-chain-amino-acid aminotransferase, cytosolictarget
Glutamic acid4-aminobutyrate aminotransferase, mitochondrialtarget
Glutamic acidGlutamate receptor ionotropic, NMDA 1target
Glutamic acidFolylpolyglutamate synthase, mitochondrialtarget
Glutamic acidGlutamyl aminopeptidasetarget
Glutamic acidGlutamate receptor ionotropic, NMDA 2Atarget
Glutamic acidGlutamate receptor ionotropic, NMDA 2Btarget
Glutamic acidGlutamate receptor ionotropic, NMDA 2Ctarget
Glutamic acidAspartate aminotransferasetarget
Glutamic acidProbable glutamate--tRNA ligase, mitochondrialtarget
Glutamic acidGlutamine-dependent NAD(+) synthetasetarget
Glutamic acidN-acetylglutamate synthase, mitochondrialtarget
Glutamic acidKynurenine/alpha-aminoadipate aminotransferase, mitochondrialtarget
Glutamic acidGlutamate receptor ionotropic, NMDA 3Atarget
Glutamic acidAlanine aminotransferase 2target
Glutamic acidAlpha-aminoadipic semialdehyde synthase, mitochondrialtarget
Glutamic acidGlutaminase liver isoform, mitochondrialtarget
Glutamic acidAspartyl aminopeptidasetarget
Glutamic acidCystine/glutamate transportertarget
Glutamic acidCarboxypeptidase Qtarget
Glutamic acidPhosphoserine aminotransferasetarget
Glutamic acidMonocarboxylate transporter 10transporter
Glutamic acidMonocarboxylate transporter 1transporter
Glutamic acidMitochondrial glutamate carrier 2transporter
Glutamic acidMitochondrial glutamate carrier 1transporter
PemetrexedThymidylate synthasetarget
PemetrexedDihydrofolate reductasetarget
PemetrexedTrifunctional purine biosynthetic protein adenosine-3target
PemetrexedDeoxycytidine kinaseenzyme
PemetrexedBifunctional purine biosynthesis protein PURHtarget
PemetrexedEquilibrative nucleoside transporter 1enzyme
PemetrexedSolute carrier family 22 member 8transporter
PemetrexedFolate transporter 1transporter
PemetrexedProton-coupled folate transportertransporter
PemetrexedATP-binding cassette sub-family G member 2transporter
PemetrexedMultidrug resistance-associated protein 5transporter
PemetrexedSolute carrier family 22 member 6transporter
PemetrexedSerum albumincarrier
PemetrexedSolute carrier family 22 member 11transporter
KetamineGlutamate receptor ionotropic, NMDA 3Atarget
KetamineNeurokinin 1 receptortarget
KetamineCytochrome P450 2B6enzyme
KetamineCytochrome P450 2C9enzyme
KetamineCytochrome P450 3A4enzyme
KetamineDopamine D2 receptortarget
KetamineProstaglandin G/H synthase 1enzyme
KetamineCytochrome P450 2C8enzyme
KetamineDelta-type opioid receptortarget
KetamineSodium-dependent noradrenaline transportertarget
KetamineKappa-type opioid receptortarget
KetamineMu-type opioid receptortarget
KetamineMuscarinic acetylcholine receptortarget
Ketamine5-hydroxytryptamine receptor 2target
Ketamine5-hydroxytryptamine receptor 1target
Ketamine5-hydroxytryptamine receptor 3Atarget
KetamineAlpha-7 nicotinic cholinergic receptor subunittarget
KetamineNitric oxide synthase, braintarget
5'-S-methyl-5'-thioadenosineModification methylase RsrItarget
5'-S-methyl-5'-thioadenosineS-methyl-5'-thioadenosine phosphorylasetarget
Glutamine hydroxamateGlutamine--fructose-6-phosphate aminotransferase [isomerizing]target
D-Aspartic AcidThermolysintarget
D-Aspartic AcidL-asparaginasetarget
Pidolic acidAlpha-amylase 2Btarget
Pidolic acidVascular endothelial growth factor Atarget
Pidolic acidPancreatic alpha-amylasetarget
Pidolic acidIg lambda-1 chain C regionstarget
Pidolic acidIg lambda chain V-II region MGCtarget
Pidolic acidTrefoil factor 2target
Pidolic acidCytochrome c2target
Pidolic acidDisintegrin and metalloproteinase domain-containing protein 28target
Pidolic acidEndo-1,4-beta-xylanasetarget
Pidolic acidDissimilatory copper-containing nitrite reductasetarget
Pidolic acidKeratin-associated protein 5-2target
Pidolic acidOrexintarget
Pidolic acidC-C motif chemokine 8target
Pidolic acidCytochrome c'target
Pidolic acidPancreatic alpha-amylaseenzyme
2s,4r-4-MethylglutamateGlutamate receptor ionotropic, kainate 2target
Sparfosic acidAspartate carbamoyltransferase catalytic chaintarget
Sparfosic acidCAD proteintarget
Beta-Hydroxyaspartic AcidBeta-lactamase TEMtarget
gamma-carboxy-L-glutamic acidProthrombintarget
gamma-carboxy-L-glutamic acidOsteocalcintarget
gamma-carboxy-L-glutamic acidCoagulation factor Xtarget
N-Carbamoylaspartic acidDihydroorotasetarget
Adenylosuccinic acidAdenylosuccinate synthetase isozyme 1target
Aspartate SemialdehydeAspartate-semialdehyde dehydrogenasetarget
Carglumic acidCarbamoyl-phosphate synthase [ammonia], mitochondrialtarget
Levomefolic acidProton-coupled folate transportertransporter
Levomefolic acidFolate transporter 1transporter
Levomefolic acidMethionine synthaseenzyme