Sulfhydryl Compounds

Name
Sulfhydryl Compounds
Accession Number
DBCAT000316
Description

Compounds containing the -SH radical.

Drugs
DrugDrug Description
2,3-Dimercapto-1-propanesulfonic acidNot Annotated
AcetylcysteineA medication that can be used as a mucolytic in patients with certain lung conditions and as an antidote for acetaminophen overdose.
AlethineInvestigated for use/treatment in blood (blood forming organ disorders, unspecified), lymphoma (unspecified), and multiple myeloma.
AzathioprineAn immunosuppressant used to prevent renal transplant rejection, treat rheumatoid arthritis, Crohn's disease, and ulcerative colitis.
BucillamineBucillamine has been used in trials studying the treatment and prevention of Gout and Rheumatoid Arthritis.
ButyrylthiocholineA sulfur-containing analog of butyrylcholine which is hydrolyzed by butyrylcholinesterase to butyrate and thiocholine. It is used as a reagent in the determination of butyrylcholinesterase activity. [PubChem]
CarbocisteineA expectorant mucolytic used in the relief of respiratory of COPD and other conditions associated with increased mucus viscosity.
CindunistatCindunistat is a small molecule drug. Cindunistat has a monoisotopic molecular weight of 219.1 Da.
Coenzyme MA uroprotective agent used for the reduction and prophylaxis of oxazaphosphorine-induced toxicity in the urinary tract.
CysteamineA cystine depleting agent used to treat the effects of cystinosis.
CysteineAn amino acid commonly found as a component of total parenteral nutrition and used as an antidote for acetaminophen overdose.
Cysteine-S-acetamideNot Available
D-pantetheine 4'-phosphateNot Available
DimercaprolA chelating agent used as an antidote to arsenic, gold, and mercury poisoning, as well as acute lead poisoning in combination with edetate calcium disodium.
Dimercaptosuccinic acidNot Annotated
ErdosteineA mucolytic agent used to treat conditions characterized by pathological mucus such as respiratory tract infections and chronic obstructive pulmonary disease (COPD).
ErgothioneineNot Annotated
LesinuradA uric acid 1 transporter inhibitor typically used in combination with a xanthine oxidase inhibitor to treat hyperuricemia associated with gout in patients with inadequate control of uric acid levels with xanthine oxidase inhibitor monotherapy.
MercaptoethanolNot Available
MercaptopurineAn antineoplastic agent used to treat acute lymphocytic leukemia.
PantenicatePantenicate is a small molecule drug. Pantenicate has a monoisotopic molecular weight of 1318.48 Da.
PantethineA naturally occurring compound derived from panthothenic acid. It acts as an intermediate in endogenous coenzyme A synthesis and is used as a dietary supplement to treat hypertriglyceridemia.
PhosphocysteamineNot Annotated
PravibismaneNot Annotated
PrenisteinePrenisteine is a small molecule drug. Prenisteine has a monoisotopic molecular weight of 189.08 Da.
RentiaprilRentiapril is a small molecule drug. The usage of the INN stem '-pril' in the name indicates that Rentiapril is a angiotensin-converting enzyme inhibitor. Rentiapril has a monoisotopic molecular weight...
S-BenzylcysteineNot Available
S-MethylcysteineNot Available
S-NitrosoglutathioneNot Annotated
S-PhosphocysteineNot Available
S-sulphocysteineNot Available
Sodium aurothiomalateA disease-modifying antirheumatic drug (DMARD) indicated for the symptomatic treatment of arthritis.
SuccimerA mercaptodicarboxylic acid heavy metal chelator used in the treatment of heavy metal poisoning.
Technetium Tc-99m succimerA radioactive diagnostic agent used as an aid in the scintigraphic evaluation of renal parenchymal disorders.
Thioglycolic acidThioglycolic acid is under investigation in clinical trial NCT03238105 (Treatment of Periorbicular Hyperchromia Comparing 10% Thioglycolic Acid Peeling Versus Pulsed Intense Light).
Drugs & Drug Targets
DrugTargetType
2,3-Dimercapto-1-propanesulfonic acidSolute carrier family 22 member 6transporter
2,3-Dimercapto-1-propanesulfonic acidOrganic anion transporter 3transporter
2,3-Dimercapto-1-propanesulfonic acidATP-binding cassette sub-family C member 2transporter
2,3-Dimercapto-1-propanesulfonic acidDelta-aminolevulinic acid dehydrataseenzyme
2,3-Dimercapto-1-propanesulfonic acidDelta-aminolevulinic acid dehydratasetarget
2,3-Dimercapto-1-propanesulfonic acidAngiotensin-converting enzymetarget
2,3-Dimercapto-1-propanesulfonic acidAngiotensin-converting enzymeenzyme
2,3-Dimercapto-1-propanesulfonic acidNa(+)/dicarboxylate cotransporter 3transporter
AcetylcysteineAminoacylase-1enzyme
AcetylcysteineAlbumincarrier
AcetylcysteineGlutamate receptor ionotropic, NMDA 3Atarget
AcetylcysteineGlutamate receptor ionotropic, NMDA 2Dtarget
AcetylcysteineGlutamate receptor ionotropic, NMDA 2Atarget
AcetylcysteineGlutamate receptor ionotropic, NMDA 1target
AcetylcysteineGlutamate receptor ionotropic, NMDA 2Btarget
AcetylcysteineCystine/glutamate transportertarget
AcetylcysteineGlutathione synthetasetarget
AcetylcysteineInhibitor of nuclear factor kappa-B kinase subunit betatarget
AcetylcysteineInhibitor of nuclear factor kappa-B kinase subunit alphatarget
AcetylcysteineAminoacylase-1target
AcetylcysteineSolute carrier family 22 member 6transporter
AcetylcysteineNAPQI (N-acetyl-p-benzoquinone imine)target
AcetylcysteineSolute carrier organic anion transporter family member 1B1transporter
AzathioprineAmidophosphoribosyltransferasetarget
AzathioprineInosine triphosphate pyrophosphataseenzyme
AzathioprineGMP synthase [glutamine-hydrolyzing]enzyme
AzathioprineThiopurine S-methyltransferaseenzyme
AzathioprineInosine-5'-monophosphate dehydrogenase 2enzyme
AzathioprineInosine-5'-monophosphate dehydrogenase 1enzyme
AzathioprineAlbumincarrier
AzathioprineEquilibrative nucleobase transporter 1transporter
AzathioprineATP-dependent translocase ABCB1transporter
AzathioprineSolute carrier family 28 member 3transporter
AzathioprineEquilibrative nucleoside transporter 2transporter
AzathioprineNucleotide triphosphate diphosphatase NUDT15enzyme
AzathioprineHypoxanthine-guanine phosphoribosyltransferaseenzyme
AzathioprineCytochrome P450 1A2enzyme
AzathioprineRas-related C3 botulinum toxin substrate 1target
AzathioprineGlutathione S-transferase Mu 1enzyme
AzathioprineGlutathione S-transferase A2enzyme
AzathioprineGlutathione S-transferase A1enzyme
AzathioprineXanthine dehydrogenase/oxidaseenzyme
BucillamineNuclear factor erythroid 2-related factor 2target
ButyrylthiocholineCholinesteraseenzyme
ButyrylthiocholineCholinesterasetarget
CarbocisteineKelch-like ECH-associated protein 1target
CarbocisteineNuclear factor erythroid 2-related factor 2target
CarbocisteineLactosylceramide alpha-2,3-sialyltransferasetarget
CarbocisteineLactosylceramide alpha-2,3-sialyltransferaseenzyme
CarbocisteinePI-PLC X domain-containing protein 3target
CarbocisteinePhenylalanine-4-hydroxylaseenzyme
CarbocisteineCysteine dioxygenase type 1enzyme
CindunistatNitric oxide synthase, inducibletarget
CysteamineSomatostatintarget
CysteamineAlbumincarrier
CysteamineMyeloperoxidaseenzyme
CysteamineCystinetarget
CysteamineNeuropeptide Y receptor type 2target
CysteineCysteine--tRNA ligase, cytoplasmictarget
CysteineGlutamate--cysteine ligase regulatory subunittarget
CysteineGlutamate--cysteine ligase catalytic subunittarget
CysteineAspartate aminotransferase, cytoplasmictarget
CysteineCystathionine gamma-lyasetarget
CysteineCystathionine beta-synthasetarget
CysteineCysteine dioxygenase type 1target
CysteineMethylated-DNA--protein-cysteine methyltransferasetarget
CysteineGlutathione synthetasetarget
CysteineProbable cysteine--tRNA ligase, mitochondrialtarget
CysteineCysteine sulfinic acid decarboxylasetarget
CysteineCysteine desulfurasetarget
CysteineMonocarboxylate transporter 10transporter
CysteineAspartate aminotransferase, mitochondrialtarget
Cysteine-S-acetamideRibonuclease pancreatictarget
Cysteine-S-acetamide2'-5'-oligoadenylate synthase 1target
D-pantetheine 4'-phosphatePhosphopantetheine adenylyltransferasetarget
D-pantetheine 4'-phosphatePhosphopantetheine adenylyltransferasetarget
D-pantetheine 4'-phosphatePhosphopantetheine adenylyltransferasetarget
DimercaprolLeadtarget
DimercaprolCadmiumtarget
DimercaprolArsenictarget
DimercaprolMercurytarget
Dimercaptosuccinic acidArsenictarget
Dimercaptosuccinic acidMercurytarget
ErdosteineChymotrypsin-like elastase family member 1target
ErdosteineAdenosine deaminaseenzyme
Ergothioneine3-mercaptopyruvate sulfurtransferasetarget
ErgothioneineSolute carrier family 22 member 4transporter
LesinuradCytochrome P450 3A4enzyme
LesinuradCytochrome P450 2C9enzyme
LesinuradSolute carrier family 22 member 11target
LesinuradSolute carrier family 22 member 12target
MercaptoethanolCarbonic anhydrase 2target
MercaptoethanolDelta-aminolevulinic acid dehydratasetarget
MercaptoethanolPeptide deformylase, mitochondrialtarget
MercaptoethanolAdenylosuccinate synthetasetarget
MercaptoethanolM-phase inducer phosphatase 2target
MercaptoethanolGlucose--fructose oxidoreductasetarget
MercaptoethanolAlpha-1-antitrypsintarget
MercaptoethanolPyridoxine/pyridoxamine 5'-phosphate oxidasetarget
MercaptoethanolGalectin-1target
MercaptoethanolPyridoxine-5'-phosphate oxidasetarget
MercaptoethanolLactoylglutathione lyasetarget
MercaptoethanolProtein ninBtarget
MercaptoethanolPolycomb protein SCMH1target
MercaptoethanolFibroblast growth factor 2target
MercaptoethanolEndolysintarget
MercaptoethanolEndonuclease IIItarget
MercaptoethanolThymidylate synthasetarget
MercaptopurineInosine-5'-monophosphate dehydrogenase 1target
MercaptopurineHypoxanthine-guanine phosphoribosyltransferasetarget
MercaptopurineOrganic anion transporter 3transporter
MercaptopurineAldehyde oxidaseenzyme
MercaptopurineEquilibrative nucleoside transporter 2transporter
MercaptopurineATP-binding cassette sub-family C member 4transporter
MercaptopurineATP-binding cassette sub-family C member 5transporter
MercaptopurineSodium/nucleoside cotransporter 2transporter
MercaptopurineInosine-5'-monophosphate dehydrogenasetarget
MercaptopurineSolute carrier family 28 member 3transporter
MercaptopurineXanthine dehydrogenase/oxidaseenzyme
MercaptopurineEquilibrative nucleoside transporter 1transporter
MercaptopurineThiopurine S-methyltransferaseenzyme
MercaptopurineAmidophosphoribosyltransferasetarget
PantethineUbiquitin C-terminal hydrolase PSMD14target
PantethinePantetheinaseenzyme
PrenisteinePrenylcysteine oxidase 1enzyme
PrenisteineProtein-S-isoprenylcysteine O-methyltransferaseenzyme
RentiaprilAngiotensin-converting enzymetarget
RentiaprilAminopeptidase RNPEPL1target
S-BenzylcysteineMethylated-DNA--protein-cysteine methyltransferasetarget
S-MethylcysteineCathepsin Dtarget
S-MethylcysteineFatty acid-binding protein, livercarrier
S-MethylcysteineMethylated-DNA--protein-cysteine methyltransferasetarget
S-NitrosoglutathioneAlcohol dehydrogenase class-3enzyme
S-NitrosoglutathioneGlutathione hydrolase 1 proenzymeenzyme
S-NitrosoglutathioneGlutathione reductase, mitochondrialenzyme
S-NitrosoglutathioneThioredoxin reductase 1, cytoplasmicenzyme
S-NitrosoglutathioneThioredoxinenzyme
S-NitrosoglutathioneV-ATPase Subunitstarget
S-PhosphocysteinePTS system N,N'-diacetylchitobiose-specific EIIB componenttarget
S-Phosphocysteine2-iminobutanoate/2-iminopropanoate deaminasetarget
S-sulphocysteineDipeptidase 1enzyme
S-sulphocysteineGlutamine synthetasetarget
S-sulphocysteineGlutamate--cysteine ligase catalytic subunittarget
S-sulphocysteineNMDA receptortarget
Sodium aurothiomalateAlbumincarrier
Sodium aurothiomalateProtein kinase C iota typetarget
Sodium aurothiomalateUDP-glucuronosyltransferase 1A1enzyme
SuccimerLeadtarget
SuccimerMercurytarget
SuccimerCadmiumtarget
SuccimerArsenictarget
Technetium Tc-99m succimerAlpha-2-macroglobulintarget
Technetium Tc-99m succimerSodium-dependent phosphate transporter 2transporter
Technetium Tc-99m succimerSodium-dependent phosphate transporter 1transporter
Thioglycolic acidMedium-chain specific acyl-CoA dehydrogenase, mitochondrialtarget