Cyclohexenes

Name
Cyclohexenes
Accession Number
DBCAT000357
Description

Cyclohexanes which contain two double bonds in the ring.

Drugs
DrugDrug Description
Vitamin AA vitamin important for retinal function that is used clinically to correct vitamin A deficiency.
AcitretinAn oral retinoid used in the treatment of severe psoriasis.
AdenosineA medication used in myocardial perfusion scintigraphy and to treat supraventricular tachycardia.
IsotretinoinA retinoid used to treat severe recalcitrant acne.
(4R)-limoneneLimonene is common in cosmetic products. As the main odor constituent of citrus (plant family Rutaceae), D-limonene is used in food manufacturing and some medicines, e.g. as a flavoring to...
Oseltamivir acidNot Available
PeridininNot Available
CrocinCrocin has been investigated for the treatment of Hyperglycemia, Metabolic Syndrome, Hypertriglyceridemia, and Hypercholesterolemia.
NorbixinNorbixin is under investigation in clinical trial NCT03820245 (Effect of Short-term Annatto Carotenoids Supplementation on Oxidative Stress Status in Healthy Individuals).
alpha-CaroteneNot Annotated
LuteinXanthophylls are taken for nutritional supplementation, and also for treating dietary shortage or imbalance.
AlitretinoinA vitamin A derivative used to treat Kaposi's sarcoma and used off label to treat chronic hand eczema and psoriasis.
TretinoinA vitamin A derivative used to treat acne vulgaris and certain types of promyelocytic leukemia, as well as various skin conditions in over-the-counter medications.
4-OxoretinolNot Available
Isochorismic AcidNot Available
Arotinoid acidArotinoid acid is a retinoic acid analog which acts as a selective RAR agonist.
Anhydrovitamin ANot Available
ViolaxanthinNot Available
N-EthylretinamideN-Ethylretinamide is the ethylamide of all-trans B-retinoic acid.
Shikimate-3-PhosphateNot Available
3-DehydroshikimateNot Available
FenretinideInvestigated for use/treatment in macular degeneration.
IRX-5183Investigated for use/treatment in adverse effects (chemotherapy) and blood (blood forming organ disorders, unspecified).
LGD-1550Investigated for use/treatment in cancer/tumors (unspecified).
AstaxanthinInvestigated for use/treatment in eye disorders/infections, cancer/tumors (unspecified), and asthma.
Beta caroteneA vitamin A precursor found in various nutritional supplements and health products.
3-Fluoro-4-{[(2R)-2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)acetyl]amino}benzoic acidNot Available
ZeaxanthinZeaxanthin is a most common carotenoid alcohols found in nature that is involved in the xanthophyll cycle. As a coexistent isomer of lutein, zeaxanthin is synthesized in plants and some...
LycopeneAn ingredient found in a variety of supplements and vitamins.
Zuretinol acetateZuretinol acetate has been used in trials studying the treatment of Impaired Dark Adaptation, RP (Retinitis Pigmentosa), Retinitis Pigmentosa (RP), and LCA (Leber Congenital Amaurosis).
MotretinideNot Annotated
13-cis-12-(3'-Carboxyphenyl)retinoic acidNot Annotated
FucoxanthinFucoxanthin is under investigation in clinical trial NCT03613740 (Effect of Fucoxanthin on the Components of the Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion). Fucoxanthin isis a marine carotenoid mainly found...
CryptoxanthinNot Annotated
PeretinoinNot Annotated
Abscisic AcidNot Annotated
TranscrocetinateInvestigated for use/treatment in cancer/tumors (unspecified), hemorrhage, hypoxia, respiratory failure, and strokes.
Limonene, (+/-)-Limonene, (+/-)- is under investigation in clinical trial NCT05525260 (Limonene for Pulmonary Nodule Chemoprevention).
Drugs & Drug Targets
DrugTargetType
Vitamin ARetinol dehydrogenase 12target
Vitamin ARetinol dehydrogenase 5target
Vitamin ARetinol dehydrogenase 13target
Vitamin ARetinol-binding protein 5carrier
Vitamin ARetinoid-binding protein 7carrier
Vitamin ARetinol-binding protein 4carrier
Vitamin ARetinol-binding protein 2carrier
Vitamin ARetinal dehydrogenase 2target
Vitamin AAldehyde dehydrogenase 1A1target
Vitamin ALecithin retinol acyltransferasetarget
Vitamin AShort-chain dehydrogenase/reductase 3target
Vitamin ARetinaldehyde dehydrogenase 3target
Vitamin AAll-trans-retinol 13,14-reductasetarget
Vitamin ARetinol dehydrogenase 11target
Vitamin ADehydrogenase/reductase SDR family member 4target
Vitamin ARetinol dehydrogenase 14target
Vitamin ARetinol dehydrogenase 8target
Vitamin ACytochrome P450 26A1enzyme
Vitamin AApolipoprotein Dtarget
Vitamin AProstaglandin-H2 D-isomerasetarget
Vitamin AAlbumincarrier
Vitamin ARetinaldehyde-binding protein 1carrier
Vitamin ARetinol-binding protein 3carrier
Vitamin ARetinol-binding protein 1carrier
Vitamin AReceptor for retinol uptake STRA6transporter
Vitamin ARetinoic acid receptor RXR-gammatarget
AcitretinRetinoic acid receptor alphatarget
AcitretinRetinoic acid receptor RXR-betatarget
AcitretinRetinoic acid receptor gammatarget
AcitretinRetinoic acid receptor betatarget
AcitretinRetinoic acid receptor RXR-gammatarget
AcitretinRetinoic acid receptor RXR-alphatarget
AcitretinAlbumincarrier
AcitretinRetinol-binding protein 1target
AcitretinRetinoic acid receptor RXRtarget
AcitretinSignal transducer and activator of transcription 3target
AdenosineAdenosine receptor A3target
AdenosineAdenosine deaminaseenzyme
AdenosineAdenosine kinaseenzyme
AdenosineAdenosine receptor A1target
AdenosineAdenosine receptor A2atarget
AdenosineAdenosine receptor A2btarget
AdenosineSolute carrier family 28 member 3transporter
AdenosineEquilibrative nucleoside transporter 1transporter
AdenosineEquilibrative nucleoside transporter 2transporter
AdenosineEquilibrative nucleoside transporter 3transporter
AdenosineEquilibrative nucleoside transporter 4transporter
AdenosineSodium/nucleoside cotransporter 1transporter
AdenosineSodium/nucleoside cotransporter 2transporter
AdenosineGap junction alpha-1 proteintransporter
AdenosineAdenylate kinase isoenzyme 1enzyme
AdenosineNucleoside diphosphate kinase Aenzyme
AdenosineNucleoside diphosphate kinase Benzyme
AdenosinePurine nucleoside phosphorylaseenzyme
AdenosineXanthine dehydrogenase/oxidaseenzyme
AdenosineAlbumincarrier
IsotretinoinRetinoic acid receptor alphatarget
IsotretinoinAlbumincarrier
IsotretinoinRetinoic acid receptor gammatarget
IsotretinoinCytochrome P450 3A4enzyme
Oseltamivir acidNeuraminidasetarget
LuteinAlbumincarrier
AlitretinoinRetinoic acid receptor alphatarget
AlitretinoinRetinoic acid receptor RXR-betatarget
AlitretinoinRetinoic acid receptor gammatarget
AlitretinoinRetinoic acid receptor betatarget
AlitretinoinRetinoic acid receptor RXR-gammatarget
AlitretinoinRetinoic acid receptor RXR-alphatarget
AlitretinoinCellular retinoic acid-binding protein 2carrier
AlitretinoinCellular retinoic acid-binding protein 1carrier
AlitretinoinATP-dependent translocase ABCB1transporter
AlitretinoinInsulin-like growth factor-binding protein 3target
AlitretinoinPregnancy-specific beta-1-glycoprotein 5target
AlitretinoinCytochrome P450 26C1target
TretinoinRetinoic acid receptor gammatarget
TretinoinRetinoic acid receptor RXR-betatarget
TretinoinAldehyde dehydrogenase 1A1target
TretinoinRetinoic acid-induced protein 3target
TretinoinRetinoic acid receptor RXR-gammatarget
TretinoinRetinal dehydrogenase 2target
TretinoinRetinoic acid receptor responder protein 1target
TretinoinCytochrome P450 2C8enzyme
TretinoinCellular retinoic acid-binding protein 1transporter
TretinoinCellular retinoic acid-binding protein 2transporter
TretinoinCytochrome P450 2B6enzyme
TretinoinCytochrome P450 3A4enzyme
TretinoinCytochrome P450 3A5enzyme
TretinoinCytochrome P450 2A6enzyme
TretinoinCytochrome P450 3A7enzyme
TretinoinCytochrome P450 2C18enzyme
TretinoinCytochrome P450 2C9enzyme
TretinoinCytochrome P450 4A11enzyme
TretinoinCytochrome P450 1A1enzyme
TretinoinRetinoic acid receptor alphatarget
TretinoinRetinoic acid receptor betatarget
TretinoinLipocalin-1target
TretinoinOdorant-binding protein 2atarget
TretinoinRetinol-binding protein 4target
TretinoinAlbumincarrier
Tretinoin[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrialtarget
TretinoinRetinoic acid receptor RXR-alphatarget
TretinoinCarcinoembryonic antigentarget
TretinoinUDP-glucuronosyltransferase 2B7enzyme
TretinoinCytochrome P450 2E1enzyme
TretinoinCytochrome P450 26A1enzyme
TretinoinCellular retinoic acid-binding protein 1target
Isochorismic AcidPhenazine biosynthesis protein PhzDtarget
Arotinoid acidRetinoic acid receptor betatarget
N-EthylretinamideRetinol-binding protein 4carrier
Shikimate-3-Phosphate3-phosphoshikimate 1-carboxyvinyltransferasetarget
Shikimate-3-Phosphate3-phosphoshikimate 1-carboxyvinyltransferasetarget
3-Dehydroshikimate3-dehydroquinate dehydratasetarget
3-Dehydroshikimate3-dehydroquinate dehydratasetarget
FenretinideRetinol-binding protein 4carrier
IRX-5183Retinoic acid receptor alphatarget
LGD-1550Retinoic acid receptor alphatarget
LGD-1550Retinoic acid receptor betatarget
LGD-1550Retinoic acid receptor gammatarget
LGD-1550Transcription factor Juntarget
AstaxanthinNF-kappa-B inhibitor alphatarget
Beta caroteneBeta,beta-carotene 15,15'-dioxygenaseenzyme
Beta caroteneFree radicalstarget
Beta caroteneVery low-density lipoprotein receptorcarrier
Beta caroteneRetinol-binding protein 1carrier
Beta caroteneRetinol-binding protein 2carrier
Beta caroteneRetinol-binding protein 3carrier
Beta caroteneRetinol-binding protein 4carrier
Beta caroteneRetinol-binding protein 5carrier
3-Fluoro-4-{[(2R)-2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)acetyl]amino}benzoic acidRetinoic acid receptor gammatarget
FucoxanthinNF-kappa-B inhibitor alphatarget