- GABA Agonists
- Accession Number
Endogenous compounds and drugs that bind to and activate GAMMA-AMINOBUTYRIC ACID receptors (RECEPTORS, GABA).
Drug Drug Description Baclofen A GABA-ergic agonist used to manage severe spasticity of cerebral or spinal origin in adult and pediatric patients. Zolpidem A sedative hypnotic used for the short-term treatment of insomnia to improve sleep latency. Progabide Indicated for the treatment of epilepsy. AZD 3355 Investigated for use/treatment in gastroesophageal reflux disease (GERD). Tramiprosate Investigated for use/treatment in strokes and alzheimer's disease. Gaboxadol Investigated for use/treatment in sleep disorders and insomnia. Adipiplon Investigated for use/treatment in insomnia and sleep disorders. Arbaclofen Placarbil Investigated for the treatment of spasticity in multiple sclerosis, acute back spasms, and GERD. Lesogaberan Lesogaberan has been used in trials studying the treatment and basic science of GERD, Reflux, Heartburn, Regurgitation, and Reflux Disease, among others. Muscimol Muscimol has been used in trials studying the treatment of Epilepsy and Parkinson's Disease. Phenibut Not Annotated Zaleplon A sedative used for short term treatment of insomnia in adults. Clobazam A benzodiazepine used as adjunct treatment in seizures associated with Lennox-Gastaut syndrome. ABP-700 ABP-700 is under investigation in clinical trial NCT02800590 (Study to Investigate the Safety and Efficacy of 3 Dosing Regimens of ABP-700 for Procedural Sedation in Adult Participants Undergoing Colonoscopy).
- Drugs & Drug Targets