- Purinergic Agents
- Accession Number
Compounds that act on PURINERGIC RECEPTORS or influence the synthesis, storage, uptake, metabolism, or release of purinergic transmitters.
Drug Drug Description Caffeine A stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to increase alertness. It is also used in to prevent and treat pulmonary complications of premature birth. Ticlopidine A platelet aggregation inhibitor used in the prevention of conditions associated with thrombi, such as stroke and transient ischemic attacks (TIA). Theophylline A xanthine used to manage the symptoms of asthma, COPD, and other lung conditions caused by reversible airflow obstruction. Adenosine A medication used in myocardial perfusion scintigraphy. Clopidogrel An antiplatelet agent used to prevent blood clots in peripheral vascular disease, coronary artery disease, and cerebrovascular disease. Enprofylline Used in the management of symptoms of asthma. Also used in the treatment of peripheral vascular diseases and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy. Aminophylline A bronchodilator consisting of theophylline that is used for the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis. Binodenoson For cardiac pharmacologic stress SPECT imaging, which is used to diagnose coronary artery disease. Tecadenoson Investigated for use/treatment in arrhythmia and atrial fibrillation. Regrelor Investigated for use/treatment in cardiac surgery, coronary artery disease, thrombosis, and transfusion. Regadenoson A coronary vasodilator used in radionuclide myocardial perfusion imaging (MPI). Cangrelor A P2Y12 platelet receptor antagonist used during percutaneous coronary intervention to reduce the risk for periprocedural myocardial infarction (MI), repeat coronary revascularization, and stent thrombosis (ST). Naxifylline Investigated for use/treatment in congestive heart failure. Vipadenant Investigated for use/treatment in parkinson's disease. Ticagrelor A P2Y12 platelet inhibitor used in patients with a history of myocardial infarction or with acute coronary syndrome (ACS) to prevent future myocardial infarction, stroke and cardiovascular death. Istradefylline A selective adenoside A2A receptor antagonist indicated in adjunct to levodopa and carbidopa for the treatment of Parkinson's Disease. 8-cyclopentyl-1,3-dipropylxanthine CPX has been used in trials studying the treatment of Cystic Fibrosis.
- Drugs & Drug Targets