Benzofurans

Name
Benzofurans
Accession Number
DBCAT000546
Description

Compounds that contain a BENZENE ring fused to a furan ring.

Drugs
DrugDrug Description
AmiodaroneA class III antiarrhythmic indicated for the treatment of recurrent hemodynamically unstable ventricular tachycardia and recurrent ventricular fibrillation.
BenzaroneBenzarone is a small molecule drug. Benzarone has a monoisotopic molecular weight of 266.09 Da.
BenzbromaroneA uricosuric agent which is taken daily for the prevention of gout flares.
BudiodaroneInvestigated for use/treatment in arrhythmia and atrial fibrillation.
ButoprozineButoprozine is a small molecule drug. Butoprozine has a monoisotopic molecular weight of 434.29 Da.
CantharidinA natured product indicated to treat molluscum contagiosum
CitalopramA selective serotonin reuptake inhibitor (SSRI) used in the treatment of depression.
DronedaroneAn antiarrhythmic agent used in the reduce the risk of hospitalization in patients with paroxysmal or persistent atrial fibrillation.
EscitalopramA selective serotonin re-uptake inhibitor used in the treatment of major depressive disorder (MDD), generalized anxiety disorder (GAD), and other select psychiatric disorders such as obsessive-compulsive disorder (OCD).
GriseofulvinAn antifungal agent used to treat a variety of superficial tinea infections and fungal infections of the fingernails and toes.
MethylcantharidimideMethylcantharidimide is under investigation in clinical trial NCT03996681 (TACE Combined With Methylcantharidimide Tablets in the Treatment of Large and Unresectable Hepatocellular Carcinoma).
VilazodoneAn antidepressant agent used for the treatment of major depressive disorder that targets the 5-HT transporter and 5-HT1A receptors.
Drugs & Drug Targets
DrugTargetType
AmiodaroneCytochrome P450 2C9enzyme
AmiodaronePeroxisome proliferator-activated receptor gamma coactivator 1-betatarget
AmiodaronePeroxisome proliferator-activated receptor alphatarget
AmiodaroneCytochrome P450 2J2enzyme
AmiodaroneSolute carrier family 22 member 2transporter
AmiodaroneBile salt export pumptransporter
AmiodaronePeroxisome proliferator-activated receptor gammatarget
AmiodaroneThyroid hormone receptortarget
AmiodaroneCytochrome P450 2A6enzyme
AmiodaroneCytochrome P450 2C19enzyme
AmiodaroneATP-dependent translocase ABCB1transporter
AmiodaroneCytochrome P450 1A1enzyme
AmiodaroneCytochrome P450 1A2enzyme
AmiodaroneVoltage-gated inwardly rectifying potassium channel KCNH2target
AmiodaroneBeta adrenergic receptortarget
AmiodaroneHERG human cardiac K+ channeltarget
AmiodaroneCytochrome P450 2C8enzyme
AmiodaroneAlbumincarrier
AmiodaroneCytochrome P450 2D6enzyme
AmiodaroneVoltage-dependent T-type calcium channel subunit alpha-1Itarget
AmiodaroneVoltage gated L-type calcium channeltarget
AmiodaroneCytochrome P450 3A4enzyme
BenzaroneProtein phosphatase EYA3target
BenzbromaroneCytochrome P450 2C9target
BenzbromaroneCytochrome P450 2C19target
BenzbromaroneSolute carrier organic anion transporter family member 1B1transporter
BenzbromaroneSolute carrier organic anion transporter family member 2B1transporter
BenzbromaroneBile salt export pumptransporter
BenzbromaroneCytochrome P450 2C19enzyme
BenzbromaroneMultidrug resistance-associated protein 1target
BenzbromaroneAnoctamin-1target
BenzbromaroneSolute carrier family 22 member 12target
BudiodaroneHuman Carboxylesterasesenzyme
CantharidinAryl hydrocarbon receptortarget
CantharidinSerine/threonine-protein phosphatase PP1-alpha catalytic subunittarget
CitalopramSodium-dependent serotonin transportertarget
CitalopramCytochrome P450 2C19enzyme
CitalopramCytochrome P450 2D6enzyme
CitalopramCytochrome P450 3A4enzyme
CitalopramATP-dependent translocase ABCB1transporter
CitalopramCytochrome P450 1A2enzyme
CitalopramHistamine H1 receptortarget
CitalopramAmine oxidase [flavin-containing] Aenzyme
CitalopramAmine oxidase [flavin-containing] Benzyme
CitalopramAldehyde oxidaseenzyme
DronedaroneAlpha-1B adrenergic receptortarget
DronedaroneOrganic anion transporter 3transporter
DronedaroneAlbumincarrier
DronedaronePotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4target
DronedaroneInward rectifier potassium channel 2target
DronedaroneVoltage-gated sodium channel alpha subunittarget
DronedaroneVoltage gated L-type calcium channeltarget
DronedaronePotassium voltage-gated channel subfamily A member 5target
DronedaroneA-type voltage-gated potassium channel KCND3target
DronedaroneAlpha-1A adrenergic receptortarget
DronedaroneBeta-1 adrenergic receptortarget
DronedaroneSodium/calcium exchanger 1target
DronedaroneAlpha-1D adrenergic receptortarget
DronedaroneAlpha-2A adrenergic receptortarget
DronedaroneAlpha-2B adrenergic receptortarget
DronedaroneAlpha-2C adrenergic receptortarget
DronedaroneVoltage-gated inwardly rectifying potassium channel KCNH2target
DronedaroneVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DronedaroneVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DronedaroneVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
DronedaroneVoltage-dependent L-type calcium channel subunit alpha-1Starget
DronedaroneVoltage-dependent L-type calcium channel subunit beta-1target
DronedaroneVoltage-dependent L-type calcium channel subunit beta-2target
DronedaroneVoltage-dependent L-type calcium channel subunit beta-3target
DronedaroneVoltage-dependent L-type calcium channel subunit beta-4target
DronedaroneCytochrome P450 2D6enzyme
DronedaroneCytochrome P450 3A4enzyme
DronedaroneATP-dependent translocase ABCB1transporter
DronedaronePotassium channel subfamily K member 2target
DronedaroneInward rectifier potassium channeltarget
DronedaroneSolute carrier family 22 member 2transporter
DronedaroneSolute carrier family 22 member 1transporter
DronedaroneSolute carrier organic anion transporter family member 1B1transporter
DronedaroneSolute carrier organic anion transporter family member 1B3transporter
DronedaronePotassium voltage-gated channel subfamily KQT member 1target
DronedaroneCytochrome P450 3A5enzyme
DronedaroneCytochrome P450 2J2enzyme
DronedaroneThyroid hormone receptor alphatarget
DronedaroneSodium channel protein type 5 subunit alphatarget
DronedaroneG protein-activated inward rectifier potassium channel 1target
Escitalopram5-hydroxytryptamine receptor 2Atarget
Escitalopram5-hydroxytryptamine receptor 1Atarget
EscitalopramAldehyde oxidaseenzyme
EscitalopramAmine oxidase [flavin-containing] Benzyme
EscitalopramAmine oxidase [flavin-containing] Aenzyme
EscitalopramD(2) dopamine receptortarget
EscitalopramAlpha-2 adrenergic receptorstarget
EscitalopramAlpha-1 adrenergic receptorstarget
EscitalopramATP-dependent translocase ABCB1transporter
EscitalopramCytochrome P450 2C19enzyme
EscitalopramHistamine H1 receptortarget
EscitalopramMuscarinic acetylcholine receptor M1target
EscitalopramSodium-dependent noradrenaline transportertarget
EscitalopramSodium-dependent dopamine transportertarget
EscitalopramCytochrome P450 2D6enzyme
EscitalopramCytochrome P450 3A4enzyme
Escitalopram5-hydroxytryptamine receptor 2Ctarget
EscitalopramSodium-dependent serotonin transportertarget
GriseofulvinTubulin beta chaintarget
GriseofulvinCytochrome P450 3A4enzyme
GriseofulvinCytochrome P450 1A2enzyme
GriseofulvinKeratin, type I cytoskeletal 12target
Vilazodone5-hydroxytryptamine receptor 1Atarget
VilazodoneCytochrome P450 3A4enzyme
VilazodoneCytochrome P450 2D6enzyme
VilazodoneSodium-dependent serotonin transportertarget
VilazodoneCytochrome P450 2C19enzyme