Carbamates
- Name
- Carbamates
- Accession Number
- DBCAT000800
- Description
Derivatives of carbamic acid, H2NC(=O)OH. Included under this heading are N-substituted and O-substituted carbamic acids. In general carbamate esters are referred to as urethanes, and polymers that include repeating units of carbamate are referred to as POLYURETHANES. Note however that polyurethanes are derived from the polymerization of ISOCYANATES and the singular term URETHANE refers to the ethyl ester of carbamic acid.
- ATC Classification
- Drugs
Drug Drug Description Meprobamate An anxiolytic drug used for the short-term management of anxiety symptoms. Carisoprodol A centrally acting muscle relaxant used to relieve the discomfort associated with various musculoskeletal conditions. Methocarbamol A CNS depressant indicated with rest, physical therapy and other treatments to control the discomfort associated with various acute musculoskeletal conditions. Albendazole A benzimidazole anthelmintic used to treat parenchymal neurocysticercosis and other helminth infections. Mebendazole A benzimidazole anthelmintic used to treat helminth infections. Diethylcarbamazine An anthelmintic used to treat filarial infections like Wuchereria bancrofti and Loa loa. Darunavir A HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies. Urethane Urethane, formerly marketed as an inactive ingredient in Profenil injection, was determined to be carcinogenic and was removed from the Canadian, US, and UK markets in 1963. Fenbendazole Fenbendazole is a benzimidazole that presents a wide spectrum anthelmintic effect. It is used against a number of gastrointestinal parasites including giardia, roundworms, hookworms, whipworms, the Taenia genus of tapeworms,... Mebutamate Mebutamate is a sedative and anxiolytic drug with anti-hypertensive (blood pressure lowering) effects comparable to those of other barbiturates but is only around 1/3rd the potency of secobarbital as a... Emylcamate Not Annotated Bethanechol A muscarinic agonist used to treat postoperative and postpartum nonobstructive functional urinary retention and neurogenic atony of the bladder with retention. Cobicistat A CYP3A inhibitor used to increase the systemic exposure of atazanavir or darunavir in combination with other antiretroviral agents in the treatment of HIV-1 infection. Carbaryl A medication used in shampoo to remove lice. Tolnaftate An antifungal agent used to treat various skin infections caused by fungi. Zafirlukast A leukotriene receptor antagonist used for prophylaxis and chronic treatment of asthma. Disulfiram A carbamate derivative used to treat alcohol addiction. Felbamate An anticonvulsant used to treat severe epilepsy. Physostigmine A cholinesterase inhibitor used to treat glaucoma and anticholinergic toxicity. Rivastigmine A cholinesterase inhibitor used to treat mild to moderate dementia in Alzheimer's and Parkinson's. Ditiocarb A chelating agent that has been used to mobilize toxic metals from the tissues of man and experimental animals. It is the main metabolite of DISULFIRAM. Ethyl N-methylcarbamate Not Available Phenserine For the treatment of Alzheimer's disease (AD). NOX-700 Investigated for use/treatment in diabetes mellitus (type 2). Ganstigmine Investigated for use/treatment in alzheimer's disease. Flubendazole Flubendazole is an anthelmintic that is used to treat worm infection in humans. It is available OTC in Europe. Thiram Thiram may be used in dermatology as a scabicide . Thiram is mainly used as a fungicide for plants and treatment for seeds, however, this use is being investigated for... Tolciclate Not Annotated Albendazole oxide Not Annotated Tetramethylthiuram monosulfide Not Annotated Ditiocarb zinc Ditiocarb Zinc is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6... Zinc dibutyldithiocarbamate Zinc dibutyldithiocarbamate is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6... Posiphen Posiphen is under investigation in clinical trial NCT02925650 (Safety, Tolerability, PK and PD of Posiphen® in Subjects With Early Alzheimer's Disease). - Drugs & Drug Targets