Carbamates
- Name
- Carbamates
- Accession Number
- DBCAT000800
- Description
Derivatives of carbamic acid, H2NC(=O)OH. Included under this heading are N-substituted and O-substituted carbamic acids. In general carbamate esters are referred to as urethanes, and polymers that include repeating units of carbamate are referred to as POLYURETHANES. Note however that polyurethanes are derived from the polymerization of ISOCYANATES and the singular term URETHANE refers to the ethyl ester of carbamic acid.
- Drugs
Drug Drug Description Albendazole A benzimidazole anthelmintic used to treat parenchymal neurocysticercosis and other helminth infections. Albendazole oxide Not Annotated Bethanechol A muscarinic agonist used to treat postoperative and postpartum nonobstructive functional urinary retention and neurogenic atony of the bladder with retention. Buntanetap Buntanetap (previously known as Posiphen) is under investigation in clinical trial NCT02925650 (Safety, Tolerability, PK and PD of Posiphen® in Subjects With Early Alzheimer's Disease). Carbaryl A medication used in shampoo to remove lice. Carisoprodol A centrally acting muscle relaxant used to relieve the discomfort associated with various musculoskeletal conditions. Cobicistat A CYP3A inhibitor used to increase the systemic exposure of atazanavir or darunavir in combination with other antiretroviral agents in the treatment of HIV-1 infection. Darunavir A HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies. Diethylcarbamazine An anthelmintic used to treat filarial infections like Wuchereria bancrofti and Loa loa. Disulfiram A carbamate derivative used to treat alcohol addiction. Ditiocarb A chelating agent that has been used to mobilize toxic metals from the tissues of man and experimental animals. It is the main metabolite of DISULFIRAM. Ditiocarb zinc Ditiocarb Zinc is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6... Emylcamate Not Annotated Ethyl N-methylcarbamate Not Available Felbamate An anticonvulsant used to treat severe epilepsy. Fenbendazole Fenbendazole is a benzimidazole that presents a wide spectrum anthelmintic effect. It is used against a number of gastrointestinal parasites including giardia, roundworms, hookworms, whipworms, the Taenia genus of tapeworms,... Flubendazole Flubendazole is an anthelmintic that is used to treat worm infection in humans. It is available OTC in Europe. Ganstigmine Investigated for use/treatment in alzheimer's disease. Liranaftate Liranaftate is a small molecule drug. Liranaftate has a monoisotopic molecular weight of 328.12 Da. Mebendazole A benzimidazole anthelmintic used to treat helminth infections. Mebutamate Mebutamate is a sedative and anxiolytic drug with anti-hypertensive (blood pressure lowering) effects comparable to those of other barbiturates but is only around 1/3rd the potency of secobarbital as a... Meprobamate An anxiolytic drug used for the short-term management of anxiety symptoms. Methocarbamol A CNS depressant indicated with rest, physical therapy and other treatments to control the discomfort associated with various acute musculoskeletal conditions. NOX-700 Investigated for use/treatment in diabetes mellitus (type 2). Phencarbamide Phencarbamide is a small molecule drug. Phencarbamide has a monoisotopic molecular weight of 328.16 Da. Phenserine For the treatment of Alzheimer's disease (AD). Physostigmine A cholinesterase inhibitor used to treat glaucoma and anticholinergic toxicity. Pyricarbate Pyricarbate is a small molecule drug. Pyricarbate has a monoisotopic molecular weight of 253.11 Da. Rivastigmine A cholinesterase inhibitor used to treat mild to moderate dementia in Alzheimer's and Parkinson's. Sulfiram Sulfiram is a small molecule drug. Sulfiram has a monoisotopic molecular weight of 264.08 Da. Tetramethylthiuram monosulfide Not Annotated Thiram Thiram may be used in dermatology as a scabicide . Thiram is mainly used as a fungicide for plants and treatment for seeds, however, this use is being investigated for... Tolciclate Not Annotated Tolnaftate An antifungal agent used to treat various skin infections caused by fungi. Urethane Urethane, formerly marketed as an inactive ingredient in Profenil injection, was determined to be carcinogenic and was removed from the Canadian, US, and UK markets in 1963. Velufenacin Velufenacin is a small molecule drug. The usage of the INN stem '-fenacin' in the name indicates that Velufenacin is a muscarinic receptor antagonist. Velufenacin is under investigation in clinical... Zafirlukast A leukotriene receptor antagonist used for prophylaxis and chronic treatment of asthma. Zinc dibutyldithiocarbamate Zinc dibutyldithiocarbamate is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6...