Expectorants

Name
Expectorants
Accession Number
DBCAT000852
Description

Agents that increase mucous excretion. Mucolytic agents, that is drugs that liquefy mucous secretions, are also included here.

ATC Classification
Drugs
DrugDrug Description
GuaifenesinAn expectorant commonly found in OTC products for the symptomatic relief from congested chests and coughs associated with cold, bronchitis, and/or other breathing illnesses.
SteproninStrepronin is a mucolytic (expectorant) drug.
CarbocisteineA expectorant mucolytic used in the relief of respiratory of COPD and other conditions associated with increased mucus viscosity.
ErdosteineA mucolytic agent used to treat conditions characterized by pathological mucus such as respiratory tract infections and chronic obstructive pulmonary disease (COPD).
AmbroxolA medication indicated for airway secretion clearance therapy.
LetosteineLetosteine is a mucolytic used in the treatment of chronic bronchopneumopathies and related conditions.
EprazinoneEprazinone (trade name Eftapan) is a mucolytic drug, and relieves bronchospasms.
BromhexineA mucolytic drug used to decrease the viscosity of mucus in the airway, enhancing mucus clearance.
SobrerolA mucolytic indicated in patients with chronic respiratory diseases.
AcetylcysteineA medication that can be used as a mucolytic in patients with certain lung conditions and as an antidote for acetaminophen overdose.
Potassium citrateAn agent used to manage renal tubular acidosis, hypocitraturic calcium oxalate nephrolithiasis, and uric acid lithiasis with or without calcium stones.
Terpin hydrateAn expectorant used to treat bronchitis, pneumonia, bronchiectasis, COPD, and infectious or inflammatory diseases of the upper respiratory tract.
CitioloneNot Annotated
GuacetisalNot Annotated
Dornase alfaA synthetic form of human deoxyribonuclease I used to break down extracellular DNA in the lungs, a major source of mucous viscosity in cystic fibrosis.
MannitolA sugar alcohol used to test for asthma, to reduce intracranial and intraocular pressure, to measure glomerular filtration rate, and to manage pulmonary symptoms associated with cystic fibrosis.
EucalyptolA common ingredient in mouthwash and cosmetics derived naturally from the eucalyptus plant that is frequently used to to improve symptoms of airway mucus hypersecretion.
TyloxapolTyloxapol is an inhaled surfactant that assists in removing and liquefying and removing bronchopulmonary secretions with mucus and pus. Tyloxapol is administered either through nebulized solution or a stream of...
Hedera helix leaf extractA plant extract indicated to treat coughing.
NeltenexineNeltenexine is an elastase inhibitor. It may be useful for preventing pulmonary emphysema.
Wood creosoteNot Annotated
IpecacAn emetic agent used to induce vomiting in poisoning.
LevoverbenoneNot Annotated
Antimony pentasulfideNot Annotated
Althea rootNot Annotated
DomiodolNot Annotated
Potassium IodideAn oral antithyroid agent used for the prevention of radioactive iodine uptake into the thyroid gland during a nuclear radiation emergency.
Coenzyme MA uroprotective agent used for the reduction and prophylaxis of oxazaphosphorine-induced toxicity in the urinary tract.
Polygala senega rootNot Annotated
Drugs & Drug Targets
DrugTargetType
GuaifenesinNMDA receptortarget
CarbocisteineCysteine dioxygenase type 1enzyme
CarbocisteinePhenylalanine-4-hydroxylaseenzyme
CarbocisteinePI-PLC X domain-containing protein 3target
CarbocisteineLactosylceramide alpha-2,3-sialyltransferaseenzyme
CarbocisteineLactosylceramide alpha-2,3-sialyltransferasetarget
ErdosteineAdenosine deaminaseenzyme
AmbroxolCytochrome P450 3A4enzyme
BromhexineTransmembrane protease serine 2target
BromhexineAngiotensin-converting enzyme 2target
BromhexineAngiotensin-converting enzyme 2enzyme
AcetylcysteineSolute carrier organic anion transporter family member 1B1transporter
AcetylcysteineNAPQI (N-acetyl-p-benzoquinone imine)target
AcetylcysteineSolute carrier family 22 member 6transporter
AcetylcysteineAminoacylase-1target
AcetylcysteineInhibitor of nuclear factor kappa-B kinase subunit alphatarget
AcetylcysteineInhibitor of nuclear factor kappa-B kinase subunit betatarget
AcetylcysteineGlutathione synthetasetarget
AcetylcysteineCystine/glutamate transportertarget
AcetylcysteineGlutamate receptor ionotropic, NMDA 2Btarget
AcetylcysteineGlutamate receptor ionotropic, NMDA 1target
AcetylcysteineGlutamate receptor ionotropic, NMDA 2Atarget
AcetylcysteineGlutamate receptor ionotropic, NMDA 2Dtarget
AcetylcysteineGlutamate receptor ionotropic, NMDA 3Atarget
AcetylcysteineSerum albumincarrier
AcetylcysteineAminoacylase-1enzyme
Dornase alfaDNAtarget
MannitolMannitol dehydrogenaseenzyme
TyloxapolLipoprotein lipasetarget
IpecacCytochrome P450 2D6enzyme
IpecacCytochrome P450 3A4enzyme
Potassium IodideTyrosinetarget